Opioid receptor trafficking and interaction in nociceptors

Delta Opioid Receptors Presynaptically Regulate Cutaneous Mechanosensory Neuron Input to the Spinal Cord Dorsal Horn

(2014) Rita Bardoni et al.   NEURON

The Concise Guide to PHARMACOLOGY 2013/14: G Protein-Coupled Receptors

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Spinal   and   Opioids Inhibit Both Thermal and Mechanical Pain in Rats

(2013) A. Normandin et al.   JOURNAL OF NEUROSCIENCE

Bradykinin Controls Pool Size of Sensory Neurons Expressing Functional  -Opioid Receptors

(2013) L. Pettinger et al.   JOURNAL OF NEUROSCIENCE

Protein Kinase C  Is Required for Spinal Analgesic Synergy between Delta Opioid and Alpha-2A Adrenergic Receptor Agonist Pairs

(2013) D. J. Schuster et al.   JOURNAL OF NEUROSCIENCE

Ligand-induced μ opioid receptor internalization in enteric neurons following chronic treatment with the opiate fentanyl

(2013) Laura Anselmi et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Disruption of δ-opioid receptor phosphorylation at Threonine 161 attenuates morphine tolerance in rats with CFA-induced inflammatory hypersensitivity

(2012) Hai-Jing Chen et al.   Neuroscience Bulletin

Interaction and regulatory functions of μ- and δ-opioid receptors in nociceptive afferent neurons

(2012) Xu Zhang et al.   Neuroscience Bulletin

Emergence of Functional Spinal Delta Opioid Receptors After Chronic Ethanol Exposure

(2011) Richard M. van Rijn et al.   BIOLOGICAL PSYCHIATRY

Transport of receptors, receptor signaling complexes and ion channels via neuropeptide-secretory vesicles

(2011) Bo Zhao et al.   CELL RESEARCH

Functional relevance of μ–δ opioid receptor heteromerization: A Role in novel signaling and implications for the treatment of addiction disorders: From a symposium on new concepts in mu-opioid pharmacology

(2011) Steven D. Stockton et al.   DRUG AND ALCOHOL DEPENDENCE

The effect of intrathecal mu, delta, kappa, and alpha-2 agonists on thermal hyperalgesia induced by mild burn on hind paw in rats

(2011) Hyun Jung Kim et al.   Journal of Anesthesia

Multiple Targets of  -Opioid Receptor-Mediated Presynaptic Inhibition at Primary Afferent A - and C-Fibers

(2011) B. Heinke et al.   JOURNAL OF NEUROSCIENCE

Activation of Spinal  - and  -Opioid Receptors Potently Inhibits Substance P Release Induced by Peripheral Noxious Stimuli

(2011) H. Beaudry et al.   JOURNAL OF NEUROSCIENCE

Heteromerization of the  - and  -Opioid Receptors Produces Ligand-Biased Antagonism and Alters  -Receptor Trafficking

(2011) L. Milan-Lobo et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Facilitation of μ-Opioid Receptor Activity by Preventing δ-Opioid Receptor-Mediated Codegradation

(2011) Shao-Qiu He et al.   NEURON

Follistatin-like 1 Suppresses Sensory Afferent Transmission by Activating Na+,K+-ATPase

(2011) Kai-Cheng Li et al.   NEURON

The Doctor's Dilemma: Opiate Analgesics and Chronic Pain

(2011) Howard L. Fields   NEURON

Mu-Opioid Receptor Coupling to Gαo Plays an Important Role in Opioid Antinociception

(2011) Jennifer T Lamberts et al.   NEUROPSYCHOPHARMACOLOGY

Genetic ablation of delta opioid receptors in nociceptive sensory neurons increases chronic pain and abolishes opioid analgesia

(2011) Claire Gaveriaux-Ruff et al.   PAIN

The delta opioid receptor: an evolving target for the treatment of brain disorders

(2011) Amynah A. Pradhan et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

How to design an opioid drug that causes reduced tolerance and dependence

(2010) Amy Chang Berger et al.   ANNALS OF NEUROLOGY

Agonists at the δ-opioid receptor modify the binding of µ-receptor agonists to the µ-δ receptor hetero-oligomer

(2010) N Kabli et al.   BRITISH JOURNAL OF PHARMACOLOGY

Sequence-Dependent Sorting of Recycling Proteins by Actin-Stabilized Endosomal Microdomains

(2010) Manojkumar A. Puthenveedu et al.   CELL

Delta opioid receptor-mediated analgesia is not altered in preprotachykinin A knockout mice

(2010) Dave Dubois et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Morphine Induces μ Opioid Receptor Endocytosis in Guinea Pig Enteric Neurons Following Prolonged Receptor Activation

(2010) Simona Patierno et al.   GASTROENTEROLOGY

Rapid Delivery of Internalized Signaling Receptors to the Somatodendritic Surface by Sequence-Specific Local Insertion

(2010) Y. J. Yu et al.   JOURNAL OF NEUROSCIENCE

Ligand-Directed Trafficking of the  -Opioid Receptor In Vivo: Two Paths Toward Analgesic Tolerance

(2010) A. A. A. Pradhan et al.   JOURNAL OF NEUROSCIENCE

Dissociation of μ- and δ-opioid Inhibition of Glutamatergic Synaptic Transmission in Superficial Dorsal Horn

(2010) Paul J Wrigley et al.   Molecular Pain

Mu and delta opioid receptors on nociceptors attenuate mechanical hyperalgesia in rat

(2010) E.K. Joseph et al.   NEUROSCIENCE

Coexpression of  - and  -opioid receptors in nociceptive sensory neurons

(2010) H.-B. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased Abundance of Opioid Receptor Heteromers After Chronic Morphine Administration

(2010) A. Gupta et al.   Science Signaling

The δ1 Opioid Receptor Is a Heterodimer That Opposes the Actions of the δ2 Receptor on Alcohol Intake

(2009) Richard M. van Rijn et al.   BIOLOGICAL PSYCHIATRY

Dissociation of the Opioid Receptor Mechanisms that Control Mechanical and Heat Pain

(2009) Grégory Scherrer et al.   CELL

Opioid-receptor-heteromer-specific trafficking and pharmacology

(2009) Richard M van Rijn et al.   CURRENT OPINION IN PHARMACOLOGY

Ubiquitination Regulates Proteolytic Processing of G Protein-coupled Receptors after Their Sorting to Lysosomes

(2009) James N. Hislop et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A functional link between T-type calcium channels and μ-opioid receptor expression in adult primary sensory neurons

(2009) Zi-Zhen Wu et al.   JOURNAL OF NEUROCHEMISTRY

Protein Kinase C Mediates the Synergistic Interaction Between Agonists Acting at  2-Adrenergic and Delta-Opioid Receptors in Spinal Cord

(2009) A. C. Overland et al.   JOURNAL OF NEUROSCIENCE

Disruption of Cdk5-Associated Phosphorylation of Residue Threonine-161 of the  -Opioid Receptor: Impaired Receptor Function and Attenuated Morphine Antinociceptive Tolerance

(2009) W.-Y. Xie et al.   JOURNAL OF NEUROSCIENCE

Bi- or multifunctional opioid peptide drugs

(2009) Peter W. Schiller   LIFE SCIENCES

Interactions of Na+,K+-ATPase and co-expressed δ-opioid receptor

(2009) Haiping Deng et al.   NEUROSCIENCE RESEARCH

In Vivo Delta Opioid Receptor Internalization Controls Behavioral Effects of Agonists

(2009) Amynah A. A. Pradhan et al.   PLoS One

Sorting of neuropeptides and neuropeptide receptors into secretory pathways

(2009) Xu Zhang et al.   PROGRESS IN NEUROBIOLOGY

Ionic storm in hypoxic/ischemic stress: Can opioid receptors subside it?

(2009) Dongman Chao et al.   PROGRESS IN NEUROBIOLOGY

Distinct Subcellular Distribution of δ-Opioid Receptor Fused with Various Tags in PC12 Cells

(2008) Hai-Bo Wang et al.   NEUROCHEMICAL RESEARCH

Short Elements with Charged Amino Acids Form Clusters to Sort Protachykinin into Large Dense-Core Vesicles

(2008) Guo-Qiang Ma et al.   TRAFFIC