SERCA2a gene therapy in heart failure: an anti-arrhythmic positive inotrope
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Title
SERCA2a gene therapy in heart failure: an anti-arrhythmic positive inotrope
Authors
Keywords
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Journal
BRITISH JOURNAL OF PHARMACOLOGY
Volume 171, Issue 1, Pages 38-54
Publisher
Wiley
Online
2013-10-21
DOI
10.1111/bph.12472
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- SERCA2a gene transfer prevents intimal proliferation in an organ culture of human internal mammary artery
- (2012) L Lipskaia et al. GENE THERAPY
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- (2012) Joshua T. Maxwell et al. JOURNAL OF PHYSIOLOGY-LONDON
- Altered sarcoplasmic reticulum calcium cycling—targets for heart failure therapy
- (2012) Changwon Kho et al. Nature Reviews Cardiology
- Aberrant S-nitrosylation mediates calcium-triggered ventricular arrhythmia in the intact heart
- (2012) M. J. Cutler et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID)
- (2011) Mariell Jessup et al. CIRCULATION
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- (2011) James N. Weiss et al. CIRCULATION RESEARCH
- SERCA2a Gene Transfer Decreases Sarcoplasmic Reticulum Calcium Leak and Reduces Ventricular Arrhythmias in a Model of Chronic Heart Failure
- (2011) Alexander R. Lyon et al. Circulation-Arrhythmia and Electrophysiology
- Changes of SERCA activity have only modest effects on sarcoplasmic reticulum Ca2+content in rat ventricular myocytes
- (2011) E. F. Bode et al. JOURNAL OF PHYSIOLOGY-LONDON
- Dose-dependent augmentation of cardiac systolic function with the selective cardiac myosin activator, omecamtiv mecarbil: a first-in-man study
- (2011) John R Teerlink et al. LANCET
- SUMO1-dependent modulation of SERCA2a in heart failure
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- (2011) Henk E. D. J. ter Keurs PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- X-ROS Signaling: Rapid Mechano-Chemo Transduction in Heart
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- Inhibition of Elevated Ca 2+ /Calmodulin-Dependent Protein Kinase II Improves Contractility in Human Failing Myocardium
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- Ca2+spark-dependent and -independent sarcoplasmic reticulum Ca2+leak in normal and failing rabbit ventricular myocytes
- (2010) Aleksey V. Zima et al. JOURNAL OF PHYSIOLOGY-LONDON
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- (2010) Lahouaria Hadri et al. MOLECULAR THERAPY
- Synergism of coupled subsarcolemmal Ca2+ clocks and sarcolemmal voltage clocks confers robust and flexible pacemaker function in a novel pacemaker cell model
- (2009) Victor A. Maltsev et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Long-Term Trends in First Hospitalization for Heart Failure and Subsequent Survival Between 1986 and 2003
- (2009) Pardeep S. Jhund et al. CIRCULATION
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- Oxygen-Wasting Effect of Inotropy
- (2009) Stig Müller et al. Circulation-Heart Failure
- Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID Trial), a First-in-Human Phase 1/2 Clinical Trial
- (2009) Brian E. Jaski et al. JOURNAL OF CARDIAC FAILURE
- Moderate heart dysfunction in mice with inducible cardiomyocyte-specific excision of the Serca2 gene
- (2009) Kristin Brevik Andersson et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Sodium accumulation promotes diastolic dysfunction in end-stage heart failure followingSerca2knockout
- (2009) William E. Louch et al. JOURNAL OF PHYSIOLOGY-LONDON
- Loss of T-tubules and other changes to surface topography in ventricular myocytes from failing human and rat heart
- (2009) A. R. Lyon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Limited functional and metabolic improvements in hypertrophic and healthy rat heart overexpressing the skeletal muscle isoform of SERCA1 by adenoviral gene transfer in vivo
- (2008) J. Michael O'Donnell et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Intracellular Ca Alternans: Coordinated Regulation by Sarcoplasmic Reticulum Release, Uptake, and Leak
- (2008) Lai-Hua Xie et al. BIOPHYSICAL JOURNAL
- Mitochondria and calcium in health and disease
- (2008) M DUCHEN et al. CELL CALCIUM
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- Gene therapy: targeting the myocardium
- (2007) A R Lyon et al. HEART
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