Therapeutic targeting of NOD1 receptors

Cross-Tolerization between Nod1 and Nod2 Signaling Results in Reduced Refractoriness to Bacterial Infection in Nod2-Deficient Macrophages

(2014) Y.-G. Kim et al.   JOURNAL OF IMMUNOLOGY

How Metabolism Generates Signals during Innate Immunity and Inflammation

(2013) Anne F. McGettrick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nucleotide Oligomerization Domain 1 Enhances IFN-  Signaling in Gastric Epithelial Cells during Helicobacter pylori Infection and Exacerbates Disease Severity

(2013) C. C. Allison et al.   JOURNAL OF IMMUNOLOGY

Roles of NOD1 (NLRC1) and NOD2 (NLRC2) in innate immunity and inflammatory diseases

(2012) Ricardo G. Correa et al.   BIOSCIENCE REPORTS

Pro-Angiogenic Activity of TLRs and NLRs: A Novel Link Between Gut Microbiota and Intestinal Angiogenesis

(2012) Anja Schirbel et al.   GASTROENTEROLOGY

Effects of polymorphisms in nucleotide-binding oligomerization domains 1 and 2 on biomarkers of the metabolic syndrome and type II diabetes

(2012) Cristina Cuda et al.   Genes and Nutrition

Vibrio choleraeO395 Outer Membrane Vesicles Modulate Intestinal Epithelial Cells in a NOD1 Protein-dependent Manner and Induce Dendritic Cell-mediated Th2/Th17 Cell Responses

(2012) Debashree Chatterjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pharmacology and therapeutic potential of pattern recognition receptors

(2012) M.J. Paul-Clark et al.   PHARMACOLOGY & THERAPEUTICS

NOD1 Activation Induces Cardiac Dysfunction and Modulates Cardiac Fibrosis and Cardiomyocyte Apoptosis

(2012) María Fernández-Velasco et al.   PLoS One

A Key Role for the Endothelium in NOD1 Mediated Vascular Inflammation: Comparison to TLR4 Responses

(2012) Timothy Gatheral et al.   PLoS One

Activation of Nod1 and Nod2 induces innate immune responses of prostate epithelial cells

(2012) Min-Jung Kang et al.   PROSTATE

Phenotyping of Nod1/2 double deficient mice and characterization of Nod1/2 in systemic inflammation and associated renal disease

(2012) I. Stroo et al.   Biology Open

NOD1 activation induces proinflammatory gene expression and insulin resistance in 3T3-L1 adipocytes

(2011) Ling Zhao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Systemic Steroids in Severe Sepsis and Septic Shock

(2011) Gourang P. Patel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Nod1 Ligands Induce Site-Specific Vascular Inflammation

(2011) Hisanori Nishio et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Lack of association between gene polymorphisms of Angiotensin converting enzyme, Nod-like receptor 1, Toll-like receptor 4, FAS/FASL and the presence of Helicobacter pylori-induced premalignant gastric lesions and gastric cancer in Caucasians

(2011) Juozas Kupcinskas et al.   BMC Medical Genetics

Viral Infection Augments Nod1/2 Signaling to Potentiate Lethality Associated with Secondary Bacterial Infections

(2011) Yun-Gi Kim et al.   Cell Host & Microbe

Discovery and Characterization of 2-Aminobenzimidazole Derivatives as Selective NOD1 Inhibitors

(2011) Ricardo G. Correa et al.   CHEMISTRY & BIOLOGY

NOD1 Activators Link Innate Immunity to Insulin Resistance

(2011) J. D. Schertzer et al.   DIABETES

Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment

(2011) Jacques Amar et al.   EMBO Molecular Medicine

Role of NOD1/CARD4 and NOD2/CARD15 gene polymorphisms in cancer etiology

(2011) Anton G. Kutikhin   HUMAN IMMUNOLOGY

Drug for Severe Sepsis Is Withdrawn From Market, Fails to Reduce Mortality

(2011) Mike Mitka   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Nucleotide-Binding Oligomerization Domain 1 Mediates Recognition of Clostridium difficile and Induces Neutrophil Recruitment and Protection against the Pathogen

(2011) M. Hasegawa et al.   JOURNAL OF IMMUNOLOGY

Identification of Inhibitors of NOD1-Induced Nuclear Factor-κB Activation

(2011) Pasha M. Khan et al.   ACS Medicinal Chemistry Letters

Nucleotide oligomerization domain 1 is a dominant pathway for NOS2 induction in vascular smooth muscle cells: comparison with Toll-like receptor 4 responses in macrophages

(2010) L Moreno et al.   BRITISH JOURNAL OF PHARMACOLOGY

Klebsiella pneumoniae subverts the activation of inflammatory responses in a NOD1-dependent manner

(2010) Verónica Regueiro et al.   CELLULAR MICROBIOLOGY

NOD2 Activation Induces Muscle Cell-Autonomous Innate Immune Responses and Insulin Resistance

(2010) Akhilesh K. Tamrakar et al.   ENDOCRINOLOGY

NOD1 and NOD2 regulation of pulmonary innate immunity to Legionella pneumophila

(2010) William R. Berrington et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Nod1 and Nod2 Are Expressed in Human and Murine Renal Tubular Epithelial Cells and Participate in Renal Ischemia Reperfusion Injury

(2010) Alana A. Shigeoka et al.   JOURNAL OF IMMUNOLOGY

Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity

(2010) Thomas B Clarke et al.   NATURE MEDICINE

Respiratory Syncytial Virus Impairs Macrophage IFN-α/β– and IFN-γ–Stimulated Transcription by Distinct Mechanisms

(2009) Albert P. Senft et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Toll-like receptors and innate immunity

(2009) Himanshu Kumar et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The significance of E266K polymorphism in the NOD1 gene on Helicobacter Pylori infection: an effective force on pathogenesis?

(2009) Banu Kara et al.   CLINICAL AND EXPERIMENTAL MEDICINE

Gut Immunity: A NOD to the Commensals

(2009) Grace Y. Chen et al.   CURRENT BIOLOGY

Neutrophil Migration During Liver Injury Is Under Nucleotide-Binding Oligomerization Domain 1 Control

(2009) Sébastien Dharancy et al.   GASTROENTEROLOGY

A Commensal Helicobacter sp. of the Rodent Intestinal Flora Activates TLR2 and NOD1 Responses in Epithelial Cells

(2009) Nadia Chaouche-Drider et al.   PLoS One

The NOD/RIP2 Pathway Is Essential for Host Defenses Against Chlamydophila pneumoniae Lung Infection

(2009) Kenichi Shimada et al.   PLoS Pathogens

The Innate Immune Receptor Nod1 Protects the Intestine from Inflammation-Induced Tumorigenesis

(2008) G. Y. Chen et al.   CANCER RESEARCH

Caspase recruitment domain-containing sensors and adaptors in intestinal innate immunity

(2008) Petr Hruz et al.   CURRENT OPINION IN GASTROENTEROLOGY

NOD-like receptors (NLRs): bona fide intracellular microbial sensors

(2008) Michael H Shaw et al.   CURRENT OPINION IN IMMUNOLOGY

The NLR Gene Family: A Standard Nomenclature

(2008) Jenny P.-Y. Ting et al.   IMMUNITY

The Cytosolic Pattern Recognition Receptor NOD1 Induces Inflammatory Interleukin-8 during Chlamydia trachomatis Infection

(2008) K. R. Buchholz et al.   INFECTION AND IMMUNITY

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(2008) Mark Paul-Clark et al.   MOLECULAR MEDICINE

Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis

(2008) Djahida Bouskra et al.   NATURE

The Roles of Pathogen-Associated Molecular Patterns in Atherosclerosis

(2008) Clett Erridge   TRENDS IN CARDIOVASCULAR MEDICINE

GEF-H1 Mediated Control of NOD1 Dependent NF-κB Activation by Shigella Effectors

(2008) Atsuko Fukazawa et al.   PLoS Pathogens