Enhancing the utility of existing antibiotics by targeting bacterial behaviour?

Quorum Sensing Inhibitors Increase the Susceptibility of Bacterial Biofilms to Antibiotics In Vitro and In Vivo

(2011) Gilles Brackman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Novel classes of antibiotics or more of the same?

(2011) Anthony RM Coates et al.   BRITISH JOURNAL OF PHARMACOLOGY

Antibiotics in the clinical pipeline in 2011

(2011) Mark S Butler et al.   JOURNAL OF ANTIBIOTICS

Novel concepts in evaluating antimicrobial therapy for bacterial lung infections in patients with cystic fibrosis

(2011) Geraint B. Rogers et al.   Journal of Cystic Fibrosis

Pseudomonas aeruginosa fosfomycin resistance mechanisms affect non-inherited fluoroquinolone tolerance

(2011) V. N. De Groote et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Role of persister cells in chronic infections: clinical relevance and perspectives on anti-persister therapies

(2011) M. Fauvart et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Rhinovirus infection liberates planktonic bacteria from biofilm and increases chemokine responses in cystic fibrosis airway epithelial cells

(2011) S. S. Chattoraj et al.   THORAX

Activities of NXL104 Combinations with Ceftazidime and Aztreonam against Carbapenemase-ProducingEnterobacteriaceae

(2010) David M. Livermore et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Evaluation of Ceftazidime and NXL104 in Two Murine Models of Infection Due to KPC-ProducingKlebsiella pneumoniae

(2010) Andrea Endimiani et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Molecular mechanisms of compounds affecting bacterial biofilm formation and dispersal

(2010) Paolo Landini et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The exclusion of dead bacterial cells is essential for accurate molecular analysis of clinical samples

(2010) G.B. Rogers et al.   CLINICAL MICROBIOLOGY AND INFECTION

How to discover new antibiotics: harvesting the parvome

(2010) Julian Davies   CURRENT OPINION IN CHEMICAL BIOLOGY

Thiazolidione derivatives as novel antibiofilm agents: Design, synthesis, biological evaluation, and structure–activity relationships

(2010) Bin Pan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Bacillus marcorestinctum sp. nov., a Novel Soil Acylhomoserine Lactone Quorum-Sensing Signal Quenching Bacterium

(2010) Yan Han et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Comment on: Antibiotic stewardship--more education and regulation not more availability?

(2010) F. J. Cooke et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Pseudomonas aeruginosa Increases Formation of Multidrug-Tolerant Persister Cells in Response to Quorum-Sensing Signaling Molecules

(2010) N. Moker et al.   JOURNAL OF BACTERIOLOGY

Emergence of Pseudomonas aeruginosa Strains Producing High Levels of Persister Cells in Patients with Cystic Fibrosis

(2010) L. R. Mulcahy et al.   JOURNAL OF BACTERIOLOGY

Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study

(2010) Karthikeyan K Kumarasamy et al.   LANCET INFECTIOUS DISEASES

Quorum sensing in bacterial virulence

(2010) L. C. M. Antunes et al.   MICROBIOLOGY-SGM

Exit from dormancy in microbial organisms

(2010) Jonathan Dworkin et al.   NATURE REVIEWS MICROBIOLOGY

How antibiotics kill bacteria: from targets to networks

(2010) Michael A. Kohanski et al.   NATURE REVIEWS MICROBIOLOGY

Different Patterns of Inappropriate Antimicrobial Use in Surgical and Medical Units at a Tertiary Care Hospital in Switzerland: A Prevalence Survey

(2010) Alexia Cusini et al.   PLoS One

Regulation of phenotypic variability by a threshold-based mechanism underlies bacterial persistence

(2010) Eitan Rotem et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

D-Amino Acids Trigger Biofilm Disassembly

(2010) I. Kolodkin-Gal et al.   SCIENCE

Revealing the dynamics of polymicrobial infections: implications for antibiotic therapy

(2010) Geraint B. Rogers et al.   TRENDS IN MICROBIOLOGY

The global need for effective antibiotics: challenges and recent advances

(2010) Liselotte Diaz Högberg et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Ciprofloxacin Causes Persister Formation by Inducing the TisB toxin in Escherichia coli

(2010) Tobias Dörr et al.   PLOS BIOLOGY

Bacteriophage Cocktail for the Prevention of Biofilm Formation by Pseudomonas aeruginosa on Catheters in an In Vitro Model System

(2009) W. Fu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Furanone at Subinhibitory Concentrations Enhances Staphylococcal Biofilm Formation by luxS Repression

(2009) R. Kuehl et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Molecular Epidemiology of KPC-Producing Klebsiella pneumoniae Isolates in the United States: Clonal Expansion of Multilocus Sequence Type 258

(2009) B. Kitchel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Characterization of a New Metallo- -Lactamase Gene, blaNDM-1, and a Novel Erythromycin Esterase Gene Carried on a Unique Genetic Structure in Klebsiella pneumoniae Sequence Type 14 from India

(2009) D. Yong et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

5-Fluorouracil reduces biofilm formation in Escherichia coli K-12 through global regulator AriR as an antivirulence compound

(2009) Can Attila et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Anti-biofilm efficacy of nitric oxide-releasing silica nanoparticles

(2009) Evan M. Hetrick et al.   BIOMATERIALS

Antibiotic use and population ecology: How you can reduce your "resistance footprint"

(2009) D. M. Patrick et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Intercellular communication in bacteria

(2009) L. Caetano M. Antunes et al.   CRITICAL REVIEWS IN MICROBIOLOGY

The role ofrpoSgene and quorum-sensing system in ofloxacin tolerance inPseudomonas aeruginosa

(2009) Shizuo Kayama et al.   FEMS MICROBIOLOGY LETTERS

Antibiotic stewardship--more education and regulation not more availability?

(2009) M. S. Dryden et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Antimicrobial and antibiofilm efficacy of triclosan and DispersinB(R) combination

(2009) R. O. Darouiche et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Nitric Oxide Signaling in Pseudomonas aeruginosa Biofilms Mediates Phosphodiesterase Activity, Decreased Cyclic Di-GMP Levels, and Enhanced Dispersal

(2009) N. Barraud et al.   JOURNAL OF BACTERIOLOGY

The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria

(2009) Patrice Nordmann et al.   LANCET INFECTIOUS DISEASES

Signals, Regulatory Networks, and Materials That Build and Break Bacterial Biofilms

(2009) E. Karatan et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Involvement of S-Nitrosylation of Actin in Inhibition of Neurotransmitter Release by Nitric Oxide

(2009) Jingshan Lu et al.   Molecular Pain

Pseudomonas aeruginosa PAO1 Preferentially Grows as Aggregates in Liquid Batch Cultures and Disperses upon Starvation

(2009) David Schleheck et al.   PLoS One

Molecular Mechanisms of HipA-Mediated Multidrug Tolerance and Its Neutralization by HipB

(2009) M. A. Schumacher et al.   SCIENCE

Antibiotics for Emerging Pathogens

(2009) M. A. Fischbach et al.   SCIENCE

Nitric oxide-mediated dispersal in single- and multi-species biofilms of clinically and industrially relevant microorganisms

(2009) Nicolas Barraud et al.   Microbial Biotechnology

SOS Response Induces Persistence to Fluoroquinolones in Escherichia coli

(2009) Tobias Dörr et al.   PLoS Genetics

Significant Reduction of Antibiotic Use in the Community after a Nationwide Campaign in France, 2002–2007

(2009) Elifsu Sabuncu et al.   PLOS MEDICINE

Bactericidal Efficacy of Nitric Oxide-Releasing Silica Nanoparticles

(2008) Evan M. Hetrick et al.   ACS Nano

Role of Global Regulators and Nucleotide Metabolism in Antibiotic Tolerance in Escherichia coli

(2008) S. Hansen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Effects of Antibiotics on Quorum Sensing in Pseudomonas aeruginosa

(2008) M. E. Skindersoe et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Brominated Furanones Inhibit Biofilm Formation by Salmonella enterica Serovar Typhimurium

(2008) J. C. A. Janssens et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Selective Killing of Nonreplicating Mycobacteria

(2008) Ruslana Bryk et al.   Cell Host & Microbe

Quorum Sensing and Quorum Quenching: The Yin and Yang of Bacterial Communication

(2008) Stéphane Uroz et al.   CHEMBIOCHEM

The biofilm life cycle and virulence of Pseudomonas aeruginosa are dependent on a filamentous prophage

(2008) Scott A Rice et al.   ISME Journal

Peroxisome Proliferator-Activated Receptors Mediate Host Cell Proinflammatory Responses to Pseudomonas aeruginosa Autoinducer

(2008) A. Jahoor et al.   JOURNAL OF BACTERIOLOGY

Failure of antibiotic treatment in microbial populations

(2008) Patrick De Leenheer et al.   JOURNAL OF MATHEMATICAL BIOLOGY

Targeting non-multiplying organisms as a way to develop novel antimicrobials

(2008) Anthony R.M. Coates et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Uracil influences quorum sensing and biofilm formation inPseudomonas aeruginosaand fluorouracil is an antagonist

(2008) Akihiro Ueda et al.   Microbial Biotechnology

Quorum sensing inhibitory drugs as next generation antimicrobials: Worth the effort?

(2008) Thomas Bjarnsholt et al.   Current Infectious Disease Reports

Poly-N-acetylglucosamine mediates biofilm formation and detergent resistance in Aggregatibacter actinomycetemcomitans

(2007) Era A. Izano et al.   MICROBIAL PATHOGENESIS