Pharmacological modulation of GITRL/GITR system: therapeutic perspectives
Published 2011 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Pharmacological modulation of GITRL/GITR system: therapeutic perspectives
Authors
Keywords
-
Journal
BRITISH JOURNAL OF PHARMACOLOGY
Volume 165, Issue 7, Pages 2089-2099
Publisher
Wiley
Online
2011-10-26
DOI
10.1111/j.1476-5381.2011.01753.x
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Development of TRX518, an aglycosyl humanized monoclonal antibody (Mab) agonist of huGITR.
- (2017) M. Rosenzweig et al. JOURNAL OF CLINICAL ONCOLOGY
- Effect of the antimouse GITR mab plus chemotherapy on survival and tumor immunity.
- (2017) J. Ponte et al. JOURNAL OF CLINICAL ONCOLOGY
- CD4+CD25lowGITR+ cells: A novel human CD4+ T-cell population with regulatory activity
- (2011) Rodolfo Bianchini et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- GITR Gene Deletion and GITR-Fc Soluble Protein Administration Inhibit Multiple Organ Failure Induced by Zymosan
- (2011) Maria Galuppo et al. SHOCK
- The glucocorticoid-induced TNF receptor family-related protein (GITR) is critical to the development of acute pancreatitis in mice
- (2010) M Galuppo et al. BRITISH JOURNAL OF PHARMACOLOGY
- Depletion of regulatory T cells by anti-GITR mAb as a novel mechanism for cancer immunotherapy
- (2010) David Coe et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- An isoleucine-zipper motif enhances costimulation of human soluble trimeric GITR ligand
- (2010) Dawei Cui et al. Cellular & Molecular Immunology
- Glucocorticoid-Induced TNFR-Related (GITR) Protein and Its Ligand in Antitumor Immunity: Functional Role and Therapeutic Modulation
- (2010) Theresa Placke et al. Clinical & Developmental Immunology
- T cell inflammatory response, Foxp3 and TNFRS18-L regulation of peripheral blood mononuclear cells from patients with nasal polyps-asthma after staphylococcal superantigen stimulation
- (2010) C. A. Pérez Novo et al. CLINICAL AND EXPERIMENTAL ALLERGY
- Blockade of GITR-GITRL interaction maintains Treg function to prolong allograft survival
- (2010) James I. Kim et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Enhancement of humoral and cellular immunity with an anti-glucocorticoid-induced tumour necrosis factor receptor monoclonal antibody
- (2010) Jose F. Ponte et al. IMMUNOLOGY
- Analysis of HLDA9 mAbs on plasmacytoid dendritic cells
- (2010) Raquel Cabezón et al. IMMUNOLOGY LETTERS
- New B-cell CD molecules
- (2010) Jessica Matesanz-Isabel et al. IMMUNOLOGY LETTERS
- Glucocorticoid-Induced TNFR family Related gene (GITR) enhances dendritic cell activity
- (2010) Simona Ronchetti et al. IMMUNOLOGY LETTERS
- GITR engagement preferentially enhances proliferation of functionally competent CD4+CD25+FoxP3+ regulatory T cells
- (2010) Gongxian Liao et al. INTERNATIONAL IMMUNOLOGY
- CD8 T Cell-Intrinsic GITR Is Required for T Cell Clonal Expansion and Mouse Survival following Severe Influenza Infection
- (2010) L. M. Snell et al. JOURNAL OF IMMUNOLOGY
- Therapeutic Glucocorticoid-Induced TNF Receptor-Mediated Amplification of CD4 + T Cell Responses Enhances Antiparasitic Immunity
- (2010) Ashraful Haque et al. JOURNAL OF IMMUNOLOGY
- Tumor-specific Crosslinking of GITR as Costimulation for Immunotherapy
- (2010) Tanja Burckhart et al. JOURNAL OF IMMUNOTHERAPY
- Mature B Cells Are Critical to T-cell-mediated Tumor Immunity Induced by an Agonist Anti-GITR Monoclonal Antibody
- (2010) Pengfei Zhou et al. JOURNAL OF IMMUNOTHERAPY
- Clinical implication of peripheral CD4+CD25+ regulatory T cells and Th17 cells in myasthenia gravis patients
- (2010) Masayuki Masuda et al. JOURNAL OF NEUROIMMUNOLOGY
- Plasmodium vivax: Induction of CD4+CD25+FoxP3+ Regulatory T Cells during Infection Are Directly Associated with Level of Circulating Parasites
- (2010) Lilian Lacerda Bueno et al. PLoS One
- Agonist Anti-GITR Monoclonal Antibody Induces Melanoma Tumor Immunity in Mice by Altering Regulatory T Cell Stability and Intra-Tumor Accumulation
- (2010) Adam D. Cohen et al. PLoS One
- Gene expression analysis of HUVEC in response to TF-binding
- (2010) Marianne Grosser et al. THROMBOSIS RESEARCH
- Identification of regulatory T cells in systemic lupus erythematosus
- (2009) Roberto Gerli et al. AUTOIMMUNITY REVIEWS
- Dendritic cells engineered to secrete anti-GITR antibodies are effective adjuvants to dendritic cell-based immunotherapy
- (2009) D Boczkowski et al. CANCER GENE THERAPY
- Glucocorticoid-Induced Tumor Necrosis Factor Receptor-Related Protein Ligand Subverts Immunosurveillance of Acute Myeloid Leukemia in Humans
- (2009) T. Baessler et al. CANCER RESEARCH
- Sequence, structure, function, immunity: structural genomics of costimulation
- (2009) Kausik Chattopadhyay et al. IMMUNOLOGICAL REVIEWS
- A novel role for Glucocorticoid-Induced TNF Receptor Ligand (Gitrl) in early embryonic zebrafish development
- (2009) Lynn D. Poulton et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
- The Glucocorticoid-Induced TNF Receptor-Related Protein (GITR)-GITR Ligand Pathway Acts As a Mediator of Cutaneous Dendritic Cell Migration and Promotes T Cell-Mediated Acquired Immunity
- (2009) Y. Kamimura et al. JOURNAL OF IMMUNOLOGY
- GITR Triggering Induces Expansion of Both Effector and Regulatory CD4+ T Cells In Vivo
- (2009) R. W. van Olffen et al. JOURNAL OF IMMUNOLOGY
- Trimer Stabilization, Oligomerization, and Antibody-Mediated Cell Surface Immobilization Improve the Activity of Soluble Trimers of CD27L, CD40L, 41BBL, and Glucocorticoid-Induced TNF Receptor Ligand
- (2009) A. Wyzgol et al. JOURNAL OF IMMUNOLOGY
- Identification of Glucocorticoid-Induced TNF Receptor-Related Protein Ligand on Keratinocytes: Ligation by GITR Induces Keratinocyte Chemokine Production and Augments T-Cell Proliferation
- (2009) Aideen M. Byrne et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Key Role of the GITR/GITRLigand Pathway in the Development of Murine Autoimmune Diabetes: A Potential Therapeutic Target
- (2009) Sylvaine You et al. PLoS One
- GITR Blockade Facilitates Treg Mediated Allograft Survival
- (2009) Samsher B. Sonawane et al. TRANSPLANTATION
- Neutralization of tumor-derived soluble Glucocorticoid-Induced TNFR-Related Protein ligand increases NK cell anti-tumor reactivity
- (2008) K. M. Baltz et al. BLOOD
- Localized expression of GITR-L in the tumor microenvironment promotes CD8+ T cell dependent anti-tumor immunity
- (2008) John S. Cho et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Construction and Preclinical Characterization of Fc-mGITRL for the Immunotherapy of Cancer
- (2008) P. Hu et al. CLINICAL CANCER RESEARCH
- Co-inhibitory roles for glucocorticoid-induced TNF receptor in CD1d-dependent natural killer T cells
- (2008) Shuming Chen et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Generation of highly suppressive adaptive CD8+CD25+FOXP3+ regulatory T cells by continuous antigen stimulation
- (2008) Milada Mahic et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The capacity of the TNF family members 4-1BBL, OX40L, CD70, GITRL, CD30L and LIGHT to costimulate human T cells
- (2008) Johanna Kober et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Tr1 and naturally occurring regulatory T cells induce IgG4 in B cells through GITR/GITR-L interaction, IL-10 and TGF-β
- (2008) Judith S. Satoguina et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Enhancement of T-cell-mediated anti-tumour immunity via the ectopically expressed glucocorticoid-induced tumour necrosis factor receptor-related receptor ligand (GITRL) on tumours
- (2008) Jinhua Piao et al. IMMUNOLOGY
- In vivo expansion of CD4+Foxp3+ regulatory T cells mediated by GITR molecules
- (2008) Tomohisa Nishioka et al. IMMUNOLOGY LETTERS
- Glucocorticoid-induced Tumor Necrosis Factor Receptor Negatively Regulates Activation of Human Primary Natural Killer (NK) Cells by Blocking Proliferative Signals and Increasing NK Cell Apoptosis
- (2008) Baoying Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Glucocorticoid-Induced Tumor Necrosis Factor Receptor-Related (GITR)-Fc Fusion Protein Inhibits GITR Triggering and Protects from the Inflammatory Response after Spinal Cord Injury
- (2008) G. Nocentini et al. MOLECULAR PHARMACOLOGY
- NGF-promoted axon growth and target innervation requires GITRL-GITR signaling
- (2008) Gerard W O'Keeffe et al. NATURE NEUROSCIENCE
- Structural basis for ligand-mediated mouse GITR activation
- (2008) Z. Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Evolution of GITRL immune function: Murine GITRL exhibits unique structural and biochemical properties within the TNF superfamily
- (2008) K. Chattopadhyay et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human glucocorticoid-induced TNF receptor ligand regulates its signaling activity through multiple oligomerization states
- (2008) Z. Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Co-Immunization of Mice with a Retroviral DNA Vaccine and GITRL-Encoding Plasmid Augments Vaccine-Induced Protection Against Retrovirus Infection
- (2008) Ulf Dittmer et al. VIRAL IMMUNOLOGY
- Reverse signaling initiated from GITRL induces NF-κB activation through ERK in the inflammatory activation of macrophages
- (2007) Eun Mi Bae et al. MOLECULAR IMMUNOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started