The relationship between the MMP system, adrenoceptors and phosphoprotein phosphatases

Distinctive Effects of Carvedilol in the Non-Infarct Zone: Remodelling of the Ligated Rat Heart Linked to Oxidative Stress

(2013) XF Zhuang et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Transactivated EGFR mediates α1-AR-induced STAT3 activation and cardiac hypertrophy

(2011) Yan Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Spironolactone Decreases Isoproterenol-Induced Ventricular Fibrosis and Matrix Metalloproteinase-2 in Rats

(2011) Yasutomo Hori et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Okadaic acid induces matrix metalloproteinase-9 expression in fibroblasts: crosstalk between protein phosphatase inhibition and β-adrenoceptor signalling

(2011) A Rietz et al.   BRITISH JOURNAL OF PHARMACOLOGY

Stress-induced epinephrine levels compromise murine dermal fibroblast activity through β-adrenoceptors

(2011) Bruna Romana-Souza et al.   EXPERIMENTAL DERMATOLOGY

Activation of β-adrenergic receptors increases the in vitro migration of malignant hepatocytes

(2011) Carly Lodewyks et al.   HEPATOLOGY RESEARCH

Nuclear Factor Kappa B and Matrix Metalloproteinase Induced Receptor Cleavage in the Spontaneously Hypertensive Rat

(2011) Kwan-I Sharon Wu et al.   HYPERTENSION

Protein phosphatase 2A affects myofilament contractility in non-failing but not in failing human myocardium

(2011) Paul J. M. Wijnker et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Inhibition of Protein Phosphatase 2A Activity by PI3Kγ Regulates β-Adrenergic Receptor Function

(2011) Neelakantan T. Vasudevan et al.   MOLECULAR CELL

Matrix metalloproteinases cleave the β2-adrenergic receptor in spontaneously hypertensive rats

(2010) Stephen F. Rodrigues et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Expression of active protein phosphatase 1 inhibitor-1 attenuates chronic beta-agonist-induced cardiac apoptosis

(2010) Guoli Chen et al.   BASIC RESEARCH IN CARDIOLOGY

The tissue inhibitors of metalloproteinases (TIMPs): An ancient family with structural and functional diversity

(2010) Keith Brew et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

α1-Adrenoceptor-mediated contraction of rat aorta is partly mediated via transactivation of the epidermal growth factor receptor

(2010) N Ulu et al.   BRITISH JOURNAL OF PHARMACOLOGY

SAR150640, a selective β3-adrenoceptor agonist, prevents human myometrial remodelling and activation of matrix metalloproteinase in an in vitro model of chorioamnionitis

(2010) F Lirussi et al.   BRITISH JOURNAL OF PHARMACOLOGY

Myocardial oxidative stress contributes to transgenic β2-adrenoceptor activation-induced cardiomyopathy and heart failure

(2010) Q Xu et al.   BRITISH JOURNAL OF PHARMACOLOGY

β2-adrenergic antagonists suppress pancreatic cancer cell invasion by inhibiting CREB, NF-κB and AP-1

(2010) Dong Zhang et al.   CANCER BIOLOGY & THERAPY

Matrix Metalloproteinase-9 Promotes Chronic Lymphocytic Leukemia B Cell Survival through Its Hemopexin Domain

(2010) Javier Redondo-Muñoz et al.   CANCER CELL

Loss of PI3Kγ Enhances cAMP-Dependent MMP Remodeling of the Myocardial N-Cadherin Adhesion Complexes and Extracellular Matrix in Response to Early Biomechanical Stress

(2010) Danny Guo et al.   CIRCULATION RESEARCH

Cutaneous wound healing of chronically stressed mice is improved through catecholamines blockade

(2010) Bruna Romana-Souza et al.   EXPERIMENTAL DERMATOLOGY

Carvedilol administration in acute myocardial infarction results in stronger inhibition of early markers of left ventricular remodeling than metoprolol

(2010) Giovanni Cimmino et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Human β1-Adrenergic Receptor Is Subject to Constitutive and Regulated N-terminal Cleavage

(2010) Anna E. Hakalahti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impact of Aldosterone Receptor Blockade on the Deleterious Cardiac Effects of Adrenergic Activation in Hypertensive Rats

(2010) Demetri G A Veliotes et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Signaling pathways of isoproterenol-induced ERK1/2 phosphorylation in primary cultures of astrocytes are concentration-dependent

(2010) Ting Du et al.   JOURNAL OF NEUROCHEMISTRY

Astrocytic transactivation by α2A-adrenergic and 5-HT2B serotonergic signaling

(2010) Liang Peng et al.   NEUROCHEMISTRY INTERNATIONAL

Protective effect of carvedilol on daunorubicin-induced cardiotoxicity and nephrotoxicity in rats

(2010) Wawaimuli Arozal et al.   TOXICOLOGY

Propranolol suppresses angiogenesis in vitro: Inhibition of proliferation, migration, and differentiation of endothelial cells

(2010) Sylvie Lamy et al.   VASCULAR PHARMACOLOGY

Pharmacological targeting of β-adrenergic receptor functions abrogates NF-κB signaling and MMP-9 secretion in medulloblastoma cells

(2010) Borhane Borhane Annabi et al.   OncoTargets and Therapy

Isoproterenol disperses distribution of NADPH oxidase, MMP-9 and pPKCε in the heart, which are mitigated by endothelin receptor antagonist CPU0213

(2009) Yu-si Cheng et al.   ACTA PHARMACOLOGICA SINICA

Doxycycline Attenuates Isoproterenol-Induced Myocardial Fibrosis and Matrix Metalloproteinase Activity in Rats

(2009) Yasutomo Hori et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Maintenance of adrenergic vascular tone by MMP transactivation of the EGFR requires PI3K and mitochondrial ATP synthesis

(2009) Prabhakara Reddy Nagareddy et al.   CARDIOVASCULAR RESEARCH

Serine/Threonine Phosphatases: Mechanism through Structure

(2009) Yigong Shi   CELL

Salbutamol up-regulates matrix metalloproteinase-9 in the alveolar space in the acute respiratory distress syndrome

(2009) Cecilia M. O’Kane et al.   CRITICAL CARE MEDICINE

Effects of AT1- and β-adrenergic receptor antagonists on TGF-β1-induced fibrosis in transgenic mice

(2009) U. Seeland et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Effect of metoprolol on vulnerable plaque in rabbits by changing shear stress around plaque and reducing inflammation

(2009) Chen Liang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Anti-inflammatory effects of formoterol and ipratropium bromide against acute cadmium-induced pulmonary inflammation in rats

(2009) Wenhui Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

β-Adrenergic stimulation and myocardial function in the failing heart

(2009) Ali El-Armouche et al.   HEART FAILURE REVIEWS

Protein phosphatase 1A (PPM1A) is involved in human cytotrophoblast cell invasion and migration

(2009) Baohua Zhang et al.   HISTOCHEMISTRY AND CELL BIOLOGY

β-Arrestin Mediates β1-Adrenergic Receptor-Epidermal Growth Factor Receptor Interaction and Downstream Signaling

(2009) Douglas G. Tilley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The extracellular matrix: At the center of it all

(2009) Stephanie L.K. Bowers et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Propranolol adrenergic blockade inhibits human brain endothelial cells tubulogenesis and matrix metalloproteinase-9 secretion

(2009) Borhane Annabi et al.   PHARMACOLOGICAL RESEARCH

 4 1 integrin and 190-kDa CD44v constitute a cell surface docking complex for gelatinase B/MMP-9 in chronic leukemic but not in normal B cells

(2008) J. Redondo-Munoz et al.   BLOOD

Phosphatase inhibitor-1-deficient mice are protected from catecholamine-induced arrhythmias and myocardial hypertrophy

(2008) Ali El-Armouche et al.   CARDIOVASCULAR RESEARCH

Functional polymorphisms in the promoter of the matrix metalloproteinase-9 (MMP-9) gene are not linked with significant plasma MMP-9 variations in healthy subjects

(2008) Caroline Demacq et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Comparison of Losartan and Carvedilol on Attenuating Inflammatory and Oxidative Response and Preserving Energy Transcription Factors and Left Ventricular Function in Dilated Cardiomyopathy Rats

(2008) Sarah Chua et al.   International Heart Journal

Transcriptional Activation of Human Matrix Metalloproteinase-9 Gene Expression by Multiple Co-activators

(2008) Xueyan Zhao et al.   JOURNAL OF MOLECULAR BIOLOGY

MMP-9 Sheds the β2Integrin Subunit (CD18) from Macrophages

(2008) Tomáš Vaisar et al.   MOLECULAR & CELLULAR PROTEOMICS

Phosphodiesterase 4 and Phosphatase 2A Differentially Regulate cAMP/Protein Kinase A Signaling for Cardiac Myocyte Contraction under Stimulation of  1 Adrenergic Receptor

(2008) V. De Arcangelis et al.   MOLECULAR PHARMACOLOGY

Differential Regulation of Matrix Metalloproteinase-9 and Tissue Plasminogen Activator Activity by the Cyclic-AMP System in Lipopolysaccharide-stimulated Rat Primary Astrocytes

(2008) Soon Young Lee et al.   NEUROCHEMICAL RESEARCH

 -Blockers alprenolol and carvedilol stimulate  -arrestin-mediated EGFR transactivation

(2008) I.-M. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MMP-9–Positive Neutrophil Infiltration Is Associated to Blood–Brain Barrier Breakdown and Basal Lamina Type IV Collagen Degradation During Hemorrhagic Transformation After Human Ischemic Stroke

(2008) Anna Rosell et al.   STROKE

EMMPRIN mediates β-adrenergic receptor-stimulated matrix metalloproteinase activity in cardiac myocytes

(2007) Deborah A. Siwik et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Fra-1 and Stat3 synergistically regulate activation of human MMP-9 gene

(2007) Yuhua Song et al.   MOLECULAR IMMUNOLOGY