Sirtuin 6 protects cardiomyocytes from hypertrophyin vitrovia inhibition of NF-κB-dependent transcriptional activity

Resveratrol (trans-3,5,4′-trihydroxystilbene) suppresses EL4 tumor growth by induction of apoptosis involving reciprocal regulation of SIRT1 and NF-κB

(2011) Narendra P. Singh et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Mammalian Sirtuins: Biological Insights and Disease Relevance

(2010) Marcia C. Haigis et al.   Annual Review of Pathology-Mechanisms of Disease

Renin-angiotensin-aldosterone system blockade for cardiovascular diseases: current status

(2010) Terry KW Ma et al.   BRITISH JOURNAL OF PHARMACOLOGY

Guidelines for reporting experiments involving animals: the ARRIVE guidelines

(2010) JC McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Sirtuin1-p53, forkhead box O3a, p38 and post-infarct cardiac remodeling in the spontaneously diabetic Goto-Kakizaki rat

(2010) Erik Vahtola et al.   Cardiovascular Diabetology

Sirt1 acts in association with PPAR  to protect the heart from hypertrophy, metabolic dysregulation, and inflammation

(2010) A. Planavila et al.   CARDIOVASCULAR RESEARCH

The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α

(2010) Lei Zhong et al.   CELL

Hepatic-Specific Disruption of SIRT6 in Mice Results in Fatty Liver Formation Due to Enhanced Glycolysis and Triglyceride Synthesis

(2010) Hyun-Seok Kim et al.   Cell Metabolism

Thioredoxin 1 Negatively Regulates Angiotensin II–Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7

(2010) Yanfei Yang et al.   CIRCULATION RESEARCH

Role of nuclear factor κB in cardiovascular health and disease

(2010) Kim van der Heiden et al.   CLINICAL SCIENCE

SIRT6 Deficiency Results in Severe Hypoglycemia by Enhancing Both Basal and Insulin-stimulated Glucose Uptake in Mice

(2010) Cuiying Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Metabolic Syndrome and Cardiovascular Risk

(2010) Salvatore Mottillo et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Chromatin regulation and genome maintenance by mammalian SIRT6

(2010) Ruth I. Tennen et al.   TRENDS IN BIOCHEMICAL SCIENCES

SIRT6 protects against pathological damage caused by diet-induced obesity

(2009) Yariv Kanfi et al.   AGING CELL

Investigating the ADP-ribosyltransferase Activity of Sirtuins with NAD Analogues and32P-NAD†

(2009) Jintang Du et al.   BIOCHEMISTRY

Sirt1 hyperexpression in SHR heart related to left ventricular hypertrophy

(2009) Ling Li et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span

(2009) Tiara L.A. Kawahara et al.   CELL

Nuclear Factor-κB Regulates Estrogen Receptor-α Transcription in the Human Heart

(2009) Shokoufeh Mahmoodzadeh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exogenous NAD Blocks Cardiac Hypertrophic Response via Activation of the SIRT3-LKB1-AMP-activated Kinase Pathway

(2009) Vinodkumar B. Pillai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recent progress in the biology and physiology of sirtuins

(2009) Toren Finkel et al.   NATURE

Effects of a Rho kinase inhibitor on pressure overload induced cardiac hypertrophy and associated diastolic dysfunction

(2008) Arintaya Phrommintikul et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Sirt7 Increases Stress Resistance of Cardiomyocytes and Prevents Apoptosis and Inflammatory Cardiomyopathy in Mice

(2008) Olesya Vakhrusheva et al.   CIRCULATION RESEARCH

Angiotensin II: A hormone involved in and contributing to pro-hypertrophic cardiac networks and target of anti-hypertrophic cross-talks

(2008) K.-D. Schlüter et al.   PHARMACOLOGY & THERAPEUTICS

Prevention of Cardiac Hypertrophy and Heart Failure by Silencing of NF-κB

(2007) Sudhiranjan Gupta et al.   JOURNAL OF MOLECULAR BIOLOGY