Mechanism of action of a nanomolar potent, allosteric antagonist of the thyroid-stimulating hormone receptor

A stimulatory TSH receptor antibody enhances adipogenesis via phosphoinositide 3-kinase activation in orbital preadipocytes from patients with Graves' ophthalmopathy

(2011) S. Kumar et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

A Small Molecule Inverse Agonist for the Human Thyroid-Stimulating Hormone Receptor

(2010) Susanne Neumann et al.   ENDOCRINOLOGY

A Novel Thyroid Stimulating Immunoglobulin Bioassay Is a Functional Indicator of Activity and Severity of Graves’ Orbitopathy

(2010) S. D. Lytton et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The Dilemma of How to Manage Graves' Hyperthyroidism in Patients with Associated Orbitopathy

(2010) Luigi Bartalena   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Species specific thyroid signal transduction: Conserved physiology, divergent mechanisms

(2010) Y. Song et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Thyrotropin Receptor-Stimulating Graves' Disease Immunoglobulins Induce Hyaluronan Synthesis by Differentiated Orbital Fibroblasts from Patients with Graves' Ophthalmopathy Not Only Via Cyclic Adenosine Monophosphate Signaling Pathways

(2010) Clementine J.J. van Zeijl et al.   THYROID

Lower levels of TSH are associated with a lower risk of papillary thyroid cancer in patients with thyroid nodular disease: thyroid autonomy may play a protective role

(2009) E Fiore et al.   ENDOCRINE-RELATED CANCER

Evidence-based treatment of Graves ophthalmopathy

(2009) Wilmar M. Wiersinga   Nature Reviews Endocrinology

A Low-Molecular-Weight Antagonist for the Human Thyrotropin Receptor with Therapeutic Potential for Hyperthyroidism

(2008) Susanne Neumann et al.   ENDOCRINOLOGY

Characterization of Thyrotropin Receptor Antibody-Induced Signaling Cascades

(2008) Syed A. Morshed et al.   ENDOCRINOLOGY

A signaling-selective, nanomolar potent allosteric low molecular weight agonist for the human luteinizing hormone receptor

(2008) Chris J. van Koppen et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Higher Serum Thyroid Stimulating Hormone Level in Thyroid Nodule Patients Is Associated with Greater Risks of Differentiated Thyroid Cancer and Advanced Tumor Stage

(2007) Megan Rist Haymart et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM