Anti-inflammatory effects of selective glucocorticoid receptor modulators are partially dependent on up-regulation of dual specificity phosphatase 1

Chromatin accessibility pre-determines glucocorticoid receptor binding patterns

(2011) Sam John et al.   NATURE GENETICS

Prednisolone-induced differential gene expression in mouse liver carrying wild type or a dimerization-defective glucocorticoid receptor

(2010) Raoul Frijters et al.   BMC GENOMICS

Glucocorticoids Suppress Bone Formation by Attenuating Osteoblast Differentiation via the Monomeric Glucocorticoid Receptor

(2010) Alexander Rauch et al.   Cell Metabolism

Targeting inflammation using selective glucocorticoid receptor modulators

(2010) Karolien De Bosscher et al.   CURRENT OPINION IN PHARMACOLOGY

Inhibition of p38 MAPK-dependent bronchial contraction after ozone by corticosteroids

(2010) F. Li et al.   EUROPEAN RESPIRATORY JOURNAL

Recent advances in the development of novel glucocorticoid receptor modulators

(2010) Michael Berlin   EXPERT OPINION ON THERAPEUTIC PATENTS

Transcriptional Regulation of Human Dual Specificity Protein Phosphatase 1 (DUSP1) Gene by Glucocorticoids

(2010) Lauren E. Shipp et al.   PLoS One

Characterization of ZK 245186, a novel, selective glucocorticoid receptor agonist for the topical treatment of inflammatory skin diseases

(2009) H Schäcke et al.   BRITISH JOURNAL OF PHARMACOLOGY

Crosstalk in Inflammation: The Interplay of Glucocorticoid Receptor-Based Mechanisms and Kinases and Phosphatases

(2009) Ilse M. E. Beck et al.   ENDOCRINE REVIEWS

Genomic determination of the glucocorticoid response reveals unexpected mechanisms of gene regulation

(2009) T. E. Reddy et al.   GENOME RESEARCH

Emerging roles of glucocorticoid receptor phosphorylation in modulating glucocorticoid hormone action in health and disease

(2009) Amy J. Galliher-Beckley et al.   IUBMB LIFE

Inhibition of NF-κB-dependent Transcription by MKP-1

(2009) Elizabeth M. King et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucocorticoid Regulation of Mouse and Human Dual Specificity Phosphatase 1 (DUSP1) Genes

(2009) Carmen R. Tchen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pharmacological strategies for improving the efficacy and therapeutic ratio of glucocorticoids in inflammatory lung diseases

(2009) Robert Newton et al.   PHARMACOLOGY & THERAPEUTICS

DNA Binding Site Sequence Directs Glucocorticoid Receptor Structure and Activity

(2009) S. H. Meijsing et al.   SCIENCE

Glucocorticoid regulation of CD38 expression in human airway smooth muscle cells: role of dual specificity phosphatase 1

(2008) Bit Na Kang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Corticosteroids Reduce IL-6 in ASM Cells via Up-Regulation of MKP-1

(2008) Timo Quante et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Inhibition of extracellular signal-regulated kinase (ERK) signaling participates in repression of nuclear factor (NF)-κB activity by glucocorticoids

(2008) Lars-Göran Bladh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Recent Developments in the Discovery of Selective Glucocorticoid Receptor Modulators (SGRMs)

(2008) Andrew Hudson et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

LGD-5552, an Antiinflammatory Glucocorticoid Receptor Ligand with Reduced Side Effects,in Vivo

(2008) Francisco J. López et al.   ENDOCRINOLOGY

Stimulation of MAPK-phosphatase 1 gene expression by glucocorticoids occurs through a tethering mechanism involving C/EBP

(2008) Krishan Johansson-Haque et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

The role of MAP kinase phosphatase-1 in the protective mechanism of dexamethasone against endotoxemia

(2008) Xianxi Wang et al.   LIFE SCIENCES

Glycogen Synthase Kinase 3 -Mediated Serine Phosphorylation of the Human Glucocorticoid Receptor Redirects Gene Expression Profiles

(2008) A. J. Galliher-Beckley et al.   MOLECULAR AND CELLULAR BIOLOGY

Restriction to Fos Family Members of Trip6-Dependent Coactivation and Glucocorticoid Receptor-DependentTrans-Repression of Activator Protein-1

(2008) Markus Diefenbacher et al.   MOLECULAR ENDOCRINOLOGY

A Novel Mitogen-Activated Protein Kinase Phosphatase-1 and Glucocorticoid Receptor (GR) Interacting Protein-1-Dependent Combinatorial Mechanism of Gene Transrepression by GR

(2008) Il Je Cho et al.   MOLECULAR ENDOCRINOLOGY