Myocardial β2-adrenoceptor gene delivery promotes coordinated cardiac adaptive remodelling and angiogenesis in heart failure

Adrenal GRK2 lowering is an underlying mechanism for the beneficial sympathetic effects of exercise training in heart failure

(2010) Giuseppe Rengo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Guidelines for reporting experiments involving animals: the ARRIVE guidelines

(2010) JC McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Impaired neoangiogenesis in β2-adrenoceptor gene-deficient mice: restoration by intravascular human β2-adrenoceptor gene transfer and role of NFκB and CREB transcription factors

(2010) Michele Ciccarelli et al.   BRITISH JOURNAL OF PHARMACOLOGY

Level of G protein–Coupled Receptor Kinase-2 Determines Myocardial Ischemia/Reperfusion Injury via Pro- and Anti-Apoptotic Mechanisms

(2010) Henriette Brinks et al.   CIRCULATION RESEARCH

Comparative Cardiac Gene Delivery of Adeno-Associated Virus Serotypes 1-9 reveals that AAV6 Mediates the Most Efficient Transduction in Mouse Heart

(2010) Carmela Zincarelli et al.   CTS-Clinical and Translational Science

Reduction of Sympathetic Activity via Adrenal-targeted GRK2 Gene Deletion Attenuates Heart Failure Progression and Improves Cardiac Function after Myocardial Infarction

(2010) Anastasios Lymperopoulos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GRK2 as a novel gene therapy target in heart failure

(2010) Giuseppe Rengo et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The Sympathetic Nervous System in Heart Failure

(2009) Filippos Triposkiadis et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

An adrenal  -arrestin 1-mediated signaling pathway underlies angiotensin II-induced aldosterone production in vitro and in vivo

(2009) A. Lymperopoulos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myocardial Adeno-Associated Virus Serotype 6–βARKct Gene Therapy Improves Cardiac Function and Normalizes the Neurohormonal Axis in Chronic Heart Failure

(2008) Giuseppe Rengo et al.   CIRCULATION

Modulation of Adrenal Catecholamine Secretion by In Vivo Gene Transfer and Manipulation of G Protein–coupled Receptor Kinase-2 Activity

(2008) Anastasios Lymperopoulos et al.   MOLECULAR THERAPY