A novel angiopoietin-derived peptide displays anti-angiogenic activity and inhibits tumour-induced and retinal neovascularization

Double Antiangiogenic Protein, DAAP, Targeting VEGF-A and Angiopoietins in Tumor Angiogenesis, Metastasis, and Vascular Leakage

(2010) Young Jun Koh et al.   CANCER CELL

Complementary Actions of Inhibitors of Angiopoietin-2 and VEGF on Tumor Angiogenesis and Growth

(2010) H. Hashizume et al.   CANCER RESEARCH

Diabetic Retinopathy: Targeting Vasoregression

(2010) H.-P. Hammes et al.   DIABETES

A Human Monoclonal Anti-ANG2 Antibody Leads to Broad Antitumor Activity in Combination with VEGF Inhibitors and Chemotherapy Agents in Preclinical Models

(2010) J. L. Brown et al.   MOLECULAR CANCER THERAPEUTICS

Context-Dependent Role of Angiopoietin-1 Inhibition in the Suppression of Angiogenesis and Tumor Growth: Implications for AMG 386, an Angiopoietin-1/2-Neutralizing Peptibody

(2010) A. Coxon et al.   MOLECULAR CANCER THERAPEUTICS

Chemical generation of bispecific antibodies

(2010) V. R. Doppalapudi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Contrasting Actions of Selective Inhibitors of Angiopoietin-1 and Angiopoietin-2 on the Normalization of Tumor Blood Vessels

(2009) Beverly L. Falcón et al.   AMERICAN JOURNAL OF PATHOLOGY

The role of the Angiopoietins in vascular morphogenesis

(2009) Markus Thomas et al.   ANGIOGENESIS

A designed angiopoietin-2 variant, pentameric COMP-Ang2, strongly activates Tie2 receptor and stimulates angiogenesis

(2009) Hak-Zoo Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Current Molecular Understanding and Future Treatment Strategies for Pathologic Ocular Neovascularization

(2009) Michael Tolentino   CURRENT MOLECULAR MEDICINE

The development of the rat model of retinopathy of prematurity

(2009) Joshua M. Barnett et al.   DOCUMENTA OPHTHALMOLOGICA

Safety, Pharmacokinetics, and Antitumor Activity of AMG 386, a Selective Angiopoietin Inhibitor, in Adult Patients With Advanced Solid Tumors

(2009) Roy S. Herbst et al.   JOURNAL OF CLINICAL ONCOLOGY

Angiopoietin 2 Is a Partial Agonist/Antagonist of Tie2 Signaling in the Endothelium

(2009) H. T. Yuan et al.   MOLECULAR AND CELLULAR BIOLOGY

Control of vascular morphogenesis and homeostasis through the angiopoietin–Tie system

(2009) Hellmut G. Augustin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Peptides modulating conformational changes in secreted chaperones: From in silico design to preclinical proof of concept

(2009) Y. Kliger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification and characterization of a novel peptide ligand of Tie2 for targeting gene therapy

(2008) Xianghua Wu et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Pericyte Migration: A Novel Mechanism of Pericyte Loss in Experimental Diabetic Retinopathy

(2008) F. Pfister et al.   DIABETES

Vascular endothelial growth factor in eye disease

(2008) J.S. Penn et al.   PROGRESS IN RETINAL AND EYE RESEARCH