Function and expression of the proton-coupled amino acid transporter PAT1 along the rat gastrointestinal tract: implications for intestinal absorption of gaboxadol

Rectal Absorption of Vigabatrin, a Substrate of the Proton Coupled Amino Acid Transporter (PAT1, Slc36a1), in Rats

(2012) René Holm et al.   PHARMACEUTICAL RESEARCH

New updated GRAC Fifth Edition with searchable online version Launch of new portal Guide to Pharmacology in association with NC-IUPHAR Transporter-Themed Issue

(2011) Steve Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Levetiracetam attenuates hippocampal expression of synaptic plasticity-related immediate early and late response genes in amygdala-kindled rats

(2010) Kenneth V Christensen et al.   BMC NEUROSCIENCE

The proton-coupled amino acid transporter, SLC36A1 (hPAT1), transports Gly-Gly, Gly-Sar and other Gly-Gly mimetics

(2010) S Frølund et al.   BRITISH JOURNAL OF PHARMACOLOGY

δ-Aminolevulinic acid is a substrate for the amino acid transporter SLC36A1 (hPAT1)

(2010) S Frølund et al.   BRITISH JOURNAL OF PHARMACOLOGY

Guidelines for reporting experiments involving animals: the ARRIVE guidelines

(2010) JC McGrath et al.   BRITISH JOURNAL OF PHARMACOLOGY

Animal research: Reporting in vivo experiments: The ARRIVE guidelines

(2010) Carol Kilkenny et al.   BRITISH JOURNAL OF PHARMACOLOGY

Gaboxadol has affinity for the proton-coupled amino acid transporter 1, SLC36A1 (hPAT1)—A modelling approach to determine IC50 values of the three ionic species of gaboxadol

(2010) Sidsel Frølund et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Coexistence of passive and carrier-mediated processes in drug transport

(2010) Kiyohiko Sugano et al.   NATURE REVIEWS DRUG DISCOVERY

Membrane transporters in drug development

(2010)   NATURE REVIEWS DRUG DISCOVERY

A novel simultaneous measurement method to assess the influence of intracerebroventricular obestatin on colonic motility and secretion in conscious rats

(2010) Chih-Yen Chen et al.   PEPTIDES

Intestinal gaboxadol absorption via PAT1 (SLC36A1): modified absorptionin vivofollowing co-administration of L-tryptophan

(2009) M Larsen et al.   BRITISH JOURNAL OF PHARMACOLOGY

5-Hydroxy-l-tryptophan alters gaboxadol pharmacokinetics in rats: Involvement of PAT1 and rOat1 in gaboxadol absorption and elimination

(2009) Mie Larsen et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Toward an Increased Understanding of the Barriers to Colonic Drug Absorption in Humans: Implications for Early Controlled Release Candidate Assessment

(2009) Christer Tannergren et al.   MOLECULAR PHARMACEUTICS

Transport of amino acids and GABA analogues via the human proton-coupled amino acid transporter, hPAT1: Characterization of conditions for affinity and transport experiments in Caco-2 cells

(2008) Mie Larsen et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Taurine uptake across the human intestinal brush-border membrane is via two transporters: H+-coupled PAT1 (SLC36A1) and Na+- and Cl−-dependent TauT (SLC6A6)

(2008) Catriona M. H. Anderson et al.   JOURNAL OF PHYSIOLOGY-LONDON

Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?

(2008) Paul D. Dobson et al.   NATURE REVIEWS DRUG DISCOVERY