Are the pharmacology and physiology of α2adrenoceptors determined by α2-heteroreceptors and autoreceptors respectively?

Chronic cardiac pressure overload induces adrenal medulla hypertrophy and increased catecholamine synthesis

(2011) Johanna Schneider et al.   BASIC RESEARCH IN CARDIOLOGY

Aspects of thermoregulation physiology

(2011) Sara Pitoni et al.   Current Opinion in Critical Care

Clonidine, an α2-receptor agonist, diminishes GABAergic neurotransmission to cardiac vagal neurons in the nucleus ambiguus

(2010) Kerry E. Philbin et al.   BRAIN RESEARCH

Sympathetic  2-adrenoceptors prevent cardiac hypertrophy and fibrosis in mice at baseline but not after chronic pressure overload

(2010) R. Gilsbach et al.   CARDIOVASCULAR RESEARCH

α2B-Adrenoceptor Deficiency Leads to Postnatal Respiratory Failure in Mice

(2010) Miriam Haubold et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reduction of Sympathetic Activity via Adrenal-targeted GRK2 Gene Deletion Attenuates Heart Failure Progression and Improves Cardiac Function after Myocardial Infarction

(2010) Anastasios Lymperopoulos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histamine regulates activities of neurons in the ventrolateral preoptic nucleus

(2010) Yu-Wei Liu et al.   JOURNAL OF PHYSIOLOGY-LONDON

Enhanced Hypotensive, Bradycardic, and Hypnotic Responses to  2-Adrenergic Agonists in Spinophilin-Null Mice Are Accompanied by Increased G Protein Coupling to the  2A-Adrenergic Receptor

(2010) R. Lu et al.   MOLECULAR PHARMACOLOGY

Teaching old receptors new tricks: biasing seven-transmembrane receptors

(2010) Sudarshan Rajagopal et al.   NATURE REVIEWS DRUG DISCOVERY

α2A-Adrenergic Receptors and Type 2 Diabetes

(2010) Fiona M. Gribble   NEW ENGLAND JOURNAL OF MEDICINE

Differential Effects of α2-adrenoceptors in the Modulation of the Thermoregulatory Response in Mice Induced by Meperidine

(2009) Jan Höcker et al.   ANESTHESIOLOGY

An Updated Focused Review of Dexmedetomidine in Adults

(2009) Anthony T Gerlach et al.   ANNALS OF PHARMACOTHERAPY

Dexmedetomidine: a review of clinical applications

(2009) Dominic S Carollo et al.   Current Opinion in Anesthesiology

Epitope-tagged Receptor Knock-in Mice Reveal That Differential Desensitization of α2-Adrenergic Responses Is because of Ligand-selective Internalization

(2009) Roujian Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulation of  2-Adrenoceptor Functions by Heterotrimeric G i Protein Isoforms

(2009) J. Albarran-Juarez et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Genetic Dissection of  2-Adrenoceptor Functions in Adrenergic versus Nonadrenergic Cells

(2009) R. Gilsbach et al.   MOLECULAR PHARMACOLOGY

α2-Adrenoceptor subtypes-mediated physiological, pharmacological actions

(2009) Klára Gyires et al.   NEUROCHEMISTRY INTERNATIONAL

Pharmacological profiles of alpha 2 adrenergic receptor agonists identified using genetically altered mice and isobolographic analysis

(2009) Carolyn A. Fairbanks et al.   PHARMACOLOGY & THERAPEUTICS

Targeting 160 Candidate Genes for Blood Pressure Regulation with a Genome-Wide Genotyping Array

(2009) Siim Sõber et al.   PLoS One

Overexpression of Alpha2A-Adrenergic Receptors Contributes to Type 2 Diabetes

(2009) A. H. Rosengren et al.   SCIENCE

Modulation of Adrenal Catecholamine Secretion by In Vivo Gene Transfer and Manipulation of G Protein–coupled Receptor Kinase-2 Activity

(2008) Anastasios Lymperopoulos et al.   MOLECULAR THERAPY

Pharmacological characterization and CNS effects of a novel highly selective α2C-adrenoceptor antagonist JP-1302

(2007) J Sallinen et al.   BRITISH JOURNAL OF PHARMACOLOGY