The SLC36 family of proton-coupled amino acid transporters and their potential role in drug transport

Renal imino acid and glycine transport system ontogeny and involvement in developmental iminoglycinuria

(2010) Jessica M. Vanslambrouck et al.   BIOCHEMICAL JOURNAL

Amino acid derivatives are substrates or non-transported inhibitors of the amino acid transporter PAT2 (slc36a2)

(2010) Noel Edwards et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Transcriptional Profiling of Equine Endometrium During the Time of Maternal Recognition of Pregnancy1

(2010) Claudia Klein et al.   BIOLOGY OF REPRODUCTION

SLC36A4 (hPAT4) Is a High Affinity Amino Acid Transporter When Expressed inXenopus laevisOocytes

(2010) Samyuktha Muralidharan Pillai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane transporters in drug development

(2010)   NATURE REVIEWS DRUG DISCOVERY

Proton-assisted amino-acid transporters are conserved regulators of proliferation and amino-acid-dependent mTORC1 activation

(2010) S Heublein et al.   ONCOGENE

Hijacking Solute Carriers for Proton-Coupled Drug Transport

(2010) Catriona M. H. Anderson et al.   PHYSIOLOGY

Intestinal gaboxadol absorption via PAT1 (SLC36A1): modified absorptionin vivofollowing co-administration of L-tryptophan

(2009) M Larsen et al.   BRITISH JOURNAL OF PHARMACOLOGY

5-Hydroxy-l-tryptophan alters gaboxadol pharmacokinetics in rats: Involvement of PAT1 and rOat1 in gaboxadol absorption and elimination

(2009) Mie Larsen et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

The role ofN-glycosylation in transport function and surface targeting of the human solute carrier PAT1

(2009) Madlen Dorn et al.   FEBS LETTERS

Orphan Transporter SLC6A18 Is Renal Neutral Amino Acid Transporter B0AT3

(2009) Dustin Singer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a Disulfide Bridge Essential for Transport Function of the Human Proton-coupled Amino Acid Transporter hPAT1

(2009) Madlen Dorn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of a blood-meal-responsive proton-dependent amino acid transporter in the disease vector, Aedes aegypti

(2009) A. M. Evans et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Transport of the Photodynamic Therapy Agent 5-Aminolevulinic Acid by Distinct H+-Coupled Nutrient Carriers Coexpressed in the Small Intestine

(2009) C. M. H. Anderson et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The Orally Active Antihyperglycemic Drug β-Guanidinopropionic Acid Is Transported by the Human Proton-Coupled Amino Acid Transporter hPAT1

(2009) Linda Metzner et al.   MOLECULAR PHARMACEUTICS

Interaction of tryptophan derivatives with SLC6A14 (ATB0,+) reveals the potential of the transporter as a drug target for cancer chemotherapy

(2008) Senthil Karunakaran et al.   BIOCHEMICAL JOURNAL

Mutational analysis of histidine residues in the human proton-coupled amino acid transporter PAT1

(2008) Linda Metzner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Transport of amino acids and GABA analogues via the human proton-coupled amino acid transporter, hPAT1: Characterization of conditions for affinity and transport experiments in Caco-2 cells

(2008) Mie Larsen et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Iminoglycinuria and hyperglycinuria are discrete human phenotypes resulting from complex mutations in proline and glycine transporters

(2008) Stefan Bröer et al.   JOURNAL OF CLINICAL INVESTIGATION

The Evolutionary History and Tissue Mapping of Amino Acid Transporters Belonging to Solute Carrier Families SLC32, SLC36, and SLC38

(2008) Björn E. Sundberg et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Taurine uptake across the human intestinal brush-border membrane is via two transporters: H+-coupled PAT1 (SLC36A1) and Na+- and Cl−-dependent TauT (SLC6A6)

(2008) Catriona M. H. Anderson et al.   JOURNAL OF PHYSIOLOGY-LONDON

Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?

(2008) Paul D. Dobson et al.   NATURE REVIEWS DRUG DISCOVERY

Amino Acid Transport Across Mammalian Intestinal and Renal Epithelia

(2008) Stefan Bröer   PHYSIOLOGICAL REVIEWS

Apical Transporters for Neutral Amino Acids: Physiology and Pathophysiology

(2008) Stefan Bröer   PHYSIOLOGY

Peptide transporters and their roles in physiological processes and drug disposition

(2008) I. Rubio-Aliaga et al.   XENOBIOTICA

Missense Mutation in Exon 2 of SLC36A1 Responsible for Champagne Dilution in Horses

(2008) Deborah Cook et al.   PLoS Genetics

Substrate specificity and functional characterisation of the H+/amino acid transporter rat PAT2 (Slc36a2)

(2004) David J Kennedy et al.   BRITISH JOURNAL OF PHARMACOLOGY