Molecular basis of selective antagonism of the P2X1 receptor for ATP by NF449 and suramin: contribution of basic amino acids in the cysteine-rich loop

Guide to Receptors and Channels (GRAC), 5th edition

(2011) SPH Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Structural interpretation of P2X receptor mutagenesis studies on drug action

(2010) Richard J Evans   BRITISH JOURNAL OF PHARMACOLOGY

Molecular Determinants of Potent P2X2 Antagonism Identified by Functional Analysis, Mutagenesis, and Homology Docking

(2010) C. Wolf et al.   MOLECULAR PHARMACOLOGY

New structure enlivens interest in P2X receptors

(2010) Liam E. Browne et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Functional Characterization of IntracellularDictyostelium discoideumP2X Receptors

(2009) Melanie J. Ludlow et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Contribution of the region Glu181 to Val200 of the extracellular loop of the human P2X1 receptor to agonist binding and gating revealed using cysteine scanning mutagenesis1

(2009) Jonathan A. Roberts et al.   JOURNAL OF NEUROCHEMISTRY

Crystal structure of the ATP-gated P2X4 ion channel in the closed state

(2009) Toshimitsu Kawate et al.   NATURE

P2X receptors: dawn of the post-structure era

(2009) Mark T. Young   TRENDS IN BIOCHEMICAL SCIENCES

Structural Characterization of Myotoxic Ecarpholin S From Echis carinatus Venom

(2008) Xingding Zhou et al.   BIOPHYSICAL JOURNAL

Cysteine Substitution Mutagenesis and the Effects of Methanethiosulfonate Reagents at P2X2and P2X4Receptors Support a Core Common Mode of ATP Action at P2X Receptors

(2008) Jonathan A. Roberts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ectodomain Lysines and Suramin Block of P2X1Receptors

(2008) Joan A. Sim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATP-gated P2X cation-channels

(2008) Michael F. Jarvis et al.   NEUROPHARMACOLOGY

Cloning and pharmacological characterization of the guinea pig P2X7receptor orthologue

(2007) E Fonfria et al.   BRITISH JOURNAL OF PHARMACOLOGY