Does airway smooth muscle express an inflammatory phenotype in asthma?

Dual Modulation of Airway Smooth Muscle Contraction by Th2 Cytokines via Matrix Metalloproteinase-1 Production

(2014) Y. Ohta et al.   JOURNAL OF IMMUNOLOGY

Cysteinyl-leukotrienes in asthmatic airway smooth muscle cell hyperplasia

(2010) Ynuk Bossé et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Non-canonical functions of RGS proteins

(2010) Nan Sethakorn et al.   CELLULAR SIGNALLING

Airway Wall Expression of OX40/OX40L and Interleukin-4 in Asthma

(2010) Salman Siddiqui et al.   CHEST

An update on the role of leukotrienes in asthma

(2010) Teal S Hallstrand et al.   Current Opinion in Allergy and Clinical Immunology

Aclidinium bromide abrogates allergen-induced hyperresponsiveness and reduces eosinophilia in murine model of airway inflammation

(2010) Gautam Damera et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Expression of IL-4 receptor α on smooth muscle cells is not necessary for development of experimental allergic asthma

(2010) Frank Kirstein et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Thymic Stromal Lymphopoietin Receptor-Mediated IL-6 and CC/CXC Chemokines Expression in Human Airway Smooth Muscle Cells: Role of MAPKs (ERK1/2, p38, and JNK) and STAT3 Pathways

(2010) L. Shan et al.   JOURNAL OF IMMUNOLOGY

Cysteinyl Leukotrienes and Their Receptors: Molecular and Functional Characteristics

(2010) R.K. Singh et al.   PHARMACOLOGY

IL-9 Induces CCL11 Expression via STAT3 Signalling in Human Airway Smooth Muscle Cells

(2010) Akira Yamasaki et al.   PLoS One

Tiotropium bromide exerts anti-inflammatory activity in a cigarette smoke mouse model of COPD

(2010) L. Wollin et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Ozone modulates IL-6 secretion in human airway epithelial and smooth muscle cells

(2009) Gautam Damera et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

TLR3 activation stimulates cytokine secretion without altering agonist-induced human small airway contraction or relaxation

(2009) Philip R. Cooper et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Airway Epithelium Stimulates Smooth Muscle Proliferation

(2009) Nikita K. Malavia et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Matrix Metalloproteinase-19 Deficiency Promotes Tenascin-C Accumulation and Allergen-Induced Airway Inflammation

(2009) Maud M. Gueders et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Gab1 transduces PI3K-mediated erythropoietin signals to the Erk pathway and regulates erythropoietin-dependent proliferation and survival of erythroid cells

(2009) Tetsuya Fukumoto et al.   CELLULAR SIGNALLING

Platelet-derived growth factor and transforming growth factor-β modulate the expression of matrix metalloproteinases and migratory function of human airway smooth muscle cells

(2009) I. Ito et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Human airway smooth muscle promotes eosinophil differentiation

(2009) A. I. Fanat et al.   CLINICAL AND EXPERIMENTAL ALLERGY

The Role of Leukotrienes in Airway Remodeling

(2009) Anjuli Mehrotra et al.   CURRENT MOLECULAR MEDICINE

Regulation of endothelin-1-induced interleukin-6 production by Ca2+ influx in human airway smooth muscle cells

(2009) Susumu Iwata et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Muscarinic M3 receptor stimulation increases cigarette smoke-induced IL-8 secretion by human airway smooth muscle cells

(2009) R. Gosens et al.   EUROPEAN RESPIRATORY JOURNAL

The role of Toll-like receptors in chronic inflammation

(2009) Stefan K. Drexler et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

RGS16 Inhibits Breast Cancer Cell Growth by Mitigating Phosphatidylinositol 3-Kinase Signaling

(2009) Genqing Liang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Der p2 activates airway smooth muscle cells in a TLR2/MyD88-dependent manner to induce an inflammatory response

(2009) Ya-Ling Chiou et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mast Cell-Dependent Contraction of Human Airway Smooth Muscle Cell-Containing Collagen Gels: Influence of Cytokines, Matrix Metalloproteases, and Serine Proteases

(2009) A. Margulis et al.   JOURNAL OF IMMUNOLOGY

Human Airway Smooth Muscle Cells from Asthmatic Individuals Have CXCL8 Hypersecretion Due to Increased NF- B p65, C/EBP , and RNA Polymerase II Binding to the CXCL8 Promoter

(2009) A. E. John et al.   JOURNAL OF IMMUNOLOGY

Increased Expression of IL-33 in Severe Asthma: Evidence of Expression by Airway Smooth Muscle Cells

(2009) D. Prefontaine et al.   JOURNAL OF IMMUNOLOGY

Role of matrix metalloproteinases in the inflammatory process of respiratory diseases

(2009) Vincent Lagente et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Fine-tuning of GPCR activity by receptor-interacting proteins

(2009) Stefanie L. Ritter et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Proinflammatory and Th2 Cytokines Regulate the High Affinity IgE Receptor (FcεRI) and IgE-Dependant Activation of Human Airway Smooth Muscle Cells

(2009) Naresh Singh Redhu et al.   PLoS One

Transcriptional regulation of cytokine function in airway smooth muscle cells

(2009) Deborah Clarke et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

TNF-α inhibitors in asthma and COPD: We must not throw the baby out with the bath water

(2009) Maria Gabriella Matera et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

TNF -induced GM-CSF release from human airway smooth muscle cells depends on activation of an ET-1 autoregulatory positive feedback mechanism

(2009) J Knobloch et al.   THORAX

Effect of β2-adrenoceptor agonists and other cAMP-elevating agents on inflammatory gene expression in human ASM cells: a role for protein kinase A

(2008) Manminder Kaur et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

PDGF-induced human airway smooth muscle cell proliferation requires STAT3 and the small GTPase Rac1

(2008) Marina C. Simeone-Penney et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The Effects of Leptin on Airway Smooth Muscle Responses

(2008) Parameswaran Nair et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Glucocorticoid- and Protein Kinase A–Dependent Transcriptome Regulation in Airway Smooth Muscle

(2008) Anna M. Misior et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Airway Smooth Muscle in Asthma

(2008) Marc B. Hershenson et al.   Annual Review of Pathology-Mechanisms of Disease

Noncontractile Functions of Airway Smooth Muscle Cells in Asthma

(2008) Omar Tliba et al.   Annual Review of Physiology

Is Airway Smooth Muscle the “Missing Link” Modulating Airway Inflammation in Asthma?

(2008) Omar Tliba et al.   CHEST

And the Winner Is … RGS4!

(2008) Richard R. Neubig   CIRCULATION RESEARCH

Eicosanoids in Asthma, Allergic Inflammation, and Host Defense

(2008) Joshua Boyce   CURRENT MOLECULAR MEDICINE

The cytokine network in asthma and chronic obstructive pulmonary disease

(2008) Peter J. Barnes   JOURNAL OF CLINICAL INVESTIGATION

Interleukin-1β up-regulates tumor necrosis factor receptors in the mouse airways

(2008) Lars Olaf Cardell et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Airway smooth muscle as an immunomodulatory cell

(2008) Gautam Damera et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Lipid metabolites as regulators of airway smooth muscle function

(2008) Deborah L. Clarke et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Tissue and matrix influences on airway smooth muscle function

(2008) Janette K. Burgess et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Airway smooth muscle in asthma: Phenotype plasticity and function

(2008) Jeremy A. Hirota et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Expression of the dystrophin-glycoprotein complex is a marker for human airway smooth muscle phenotype maturation

(2007) Pawan Sharma et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

β-Tryptase Regulates IL-8 Expression in Airway Smooth Muscle Cells by a PAR-2–Independent Mechanism

(2007) Charlotte S. Mullan et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Nuclear translocation of p65 NF-κB is sufficient for VCAM-1, but not ICAM-1, expression in TNF-stimulated smooth muscle cells: Differential requirement for PARP-1 expression and interaction

(2007) Mourad Zerfaoui et al.   CELLULAR SIGNALLING

Targeting TNF-α: A novel therapeutic approach for asthma

(2007) Christopher Brightling et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY