Characterization of RO4583298 as a novel potent, dual antagonist with in vivo activity at tachykinin NK1 and NK3 receptors

Discovery of potent, balanced and orally active dual NK1/NK3 receptor ligands

(2010) Jens-Uwe Peters et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Substance P in Stress and Anxiety

(2009) Karl Ebner et al.   Annals of the New York Academy of Sciences

Characterization of species-related differences in the pharmacology of tachykinin NK receptors 1, 2 and 3

(2009) Agnes Leffler et al.   BIOCHEMICAL PHARMACOLOGY

Tachykinin Receptors as Therapeutic Targets in Stress-Related Disorders

(2009) Karl Ebner et al.   CURRENT PHARMACEUTICAL DESIGN

Tachykinin receptor antagonists in clinical trials

(2009) Laura Quartara et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Identification of a Critical Residue in the Transmembrane Domain 2 of Tachykinin Neurokinin 3 Receptor Affecting the Dissociation Kinetics and Antagonism Mode of Osanetant (SR 142801) and Piperidine-Based Structures

(2009) Pari Malherbe et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pharmacological characterization of senktide-induced tail whips

(2009) Rebecca E. Nordquist et al.   NEUROPHARMACOLOGY

Guide to Receptors and Channels (GRAC), 3rd edition

(2008) S P H Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

The tachykinin NK3 receptor agonist senktide induces locomotor activity in male Mongolian gerbils

(2008) Rebecca E. Nordquist et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Psychomotor and cognitive effects of a single oral dose of talnetant (SB223412) in healthy volunteers compared with placebo or haloperidol

(2008) M. Liem-Moolenaar et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Me-Talnetant and Osanetant Interact within Overlapping but Not Identical Binding Pockets in the Human Tachykinin Neurokinin 3 Receptor Transmembrane Domains

(2008) P. Malherbe et al.   MOLECULAR PHARMACOLOGY

Cognitive performance in neurokinin 3 receptor knockout mice

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