Stabilization of cysteine-linked antibody drug conjugates with N-aryl maleimides

Published 2015 View Full Article

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Title
Stabilization of cysteine-linked antibody drug conjugates with N-aryl maleimides
Authors
Keywords
Antibody-drug conjugate, Maleimide, Retro-Michael reaction, Serum stability, Thiol conjugation, Thiosuccinimide hydrolysis
Journal
JOURNAL OF CONTROLLED RELEASE
Volume 220, Issue -, Pages 660-670
Publisher
Elsevier BV
Online
2015-09-25
DOI
10.1016/j.jconrel.2015.09.032

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