The anti-allergic compound tranilast attenuates inflammation and inhibits bone destruction in collagen-induced arthritis in mice

Mast Cells Contribute to Autoimmune Inflammatory Arthritis via Their Tryptase/Heparin Complexes

(2014) K. Shin et al.   JOURNAL OF IMMUNOLOGY

Histamine Promotes Osteoclastogenesis through the Differential Expression of Histamine Receptors on Osteoclasts and Osteoblasts

(2009) Martin Biosse-Duplan et al.   AMERICAN JOURNAL OF PATHOLOGY

RANK/RANKL: Regulators of Immune Responses and Bone Physiology

(2009) Andreas Leibbrandt et al.   Annals of the New York Academy of Sciences

Tranilast, an orally active anti-allergic drug, up-regulates the anti-inflammatory heme oxygenase-1 expression but down-regulates the pro-inflammatory cyclooxygenase-2 and inducible nitric oxide synthase expression in RAW264.7 macrophages

(2008) Hyun-Ock Pae et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Suppressive Effects of Tranilast on Eotaxin-1 Production from Cultured Conjunctival Fibroblasts

(2008) Richard Yudi Hida et al.   CURRENT EYE RESEARCH

Mast cell chymase contributes to the antibody response and the severity of autoimmune arthritis

(2008) Sofia E. Magnusson et al.   FASEB JOURNAL

The role and therapeutic implications of fibroblast-like synoviocytes in inflammation and cartilage erosion in rheumatoid arthritis

(2008) Erika H. Noss et al.   IMMUNOLOGICAL REVIEWS

Role of cytokines in rheumatoid arthritis: an education in pathophysiology and therapeutics

(2008) Marc Feldmann et al.   IMMUNOLOGICAL REVIEWS

The extended cleavage specificity of the rodent β-chymases rMCP-1 and mMCP-4 reveal major functional similarities to the human mast cell chymase

(2007) Mattias K. Andersson et al.   MOLECULAR IMMUNOLOGY