Dysregulation of epithelial Na+ absorption induced by inhibition of the kinases TORC1 and TORC2

Effects of nominally selective inhibitors of the kinases PI3K, SGK1 and PKB on the insulin-dependent control of epithelial Na+ absorption

(2010) Morag K Mansley et al.   BRITISH JOURNAL OF PHARMACOLOGY

mTOR Complex-2 Activates ENaC by Phosphorylating SGK1

(2010) M. Lu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mineralocorticoid and Glucocorticoid Receptors Stimulate Epithelial Sodium Channel Activity in a Mouse Model of Cushing Syndrome

(2009) Matthew A. Bailey et al.   HYPERTENSION

An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1

(2009) Carson C. Thoreen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rapamycin inhibits oncogenic intestinal ion channels and neoplasia in APCMin/+ mice

(2009) G E Koehl et al.   ONCOGENE

Regulated sodium transport in the renal connecting tubule (CNT) via the epithelial sodium channel (ENaC)

(2009) Johannes Loffing et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Epithelial sodium channel regulated by differential composition of a signaling complex

(2009) R. Soundararajan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2

(2009) Morris E Feldman et al.   PLOS BIOLOGY

mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)

(2008) Juan M. García-Martínez et al.   BIOCHEMICAL JOURNAL

Induction of serum- and glucocorticoid-induced kinase-1 (SGK1) by cAMP regulates increases in α-ENaC

(2008) Margarita M. Vasquez et al.   JOURNAL OF CELLULAR PHYSIOLOGY

SGK1 activity in Na+ absorbing airway epithelial cells monitored by assaying NDRG1-Thr346/356/366 phosphorylation

(2008) S. K. Inglis et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Thiazolidinedione insulin sensitizers and the heart: a tale of two organs?

(2007) R. E. Buckingham et al.   DIABETES OBESITY & METABOLISM