Pharmacology of epigenetics in brain disorders

Molecular Determinants of Dysregulated GABAergic Gene Expression in the Prefrontal Cortex of Subjects with Schizophrenia

(2009) Nikolaos Mellios et al.   BIOLOGICAL PSYCHIATRY

Recent advances in postmortem pathology and neurochemistry in schizophrenia

(2009) Brian Dean et al.   CURRENT OPINION IN PSYCHIATRY

Amelioration of cognitive deficits and neurodegeneration by curcumin in rat model of sporadic dementia of Alzheimer's type (SDAT)☆

(2009) Tauheed Ishrat et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

The Bifunctional microRNA miR-9/miR-9* Regulates REST and CoREST and Is Downregulated in Huntington's Disease

(2009) A. N. Packer et al.   JOURNAL OF NEUROSCIENCE

Histone deacetylase inhibitors and candidate gene expression: An in vivo and in vitro approach to studying chromatin remodeling in a clinical population

(2009) David P. Gavin et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse

(2009) Patrick O McGowan et al.   NATURE NEUROSCIENCE

Epigenetic inheritance during the cell cycle

(2009) Aline V. Probst et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Micro-RNA abundance and stability in human brain: Specific alterations in Alzheimer's disease temporal lobe neocortex

(2009) Prerna Sethi et al.   NEUROSCIENCE LETTERS

Fe65 is required for Tip60-directed histone H4 acetylation at DNA strand breaks

(2009) M. Stante et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A MicroRNA gene is hosted in an intron of a schizophrenia-susceptibility gene

(2009) Yanglong Zhu et al.   SCHIZOPHRENIA RESEARCH

Endophenotypes in schizophrenia: A selective review

(2009) Allyssa J. Allen et al.   SCHIZOPHRENIA RESEARCH

Efficacy of a Vitamin/Nutriceutical Formulation for Early-stage Alzheimer's Disease: A 1-year, Open-label Pilot Study With an 16-Month Caregiver Extension

(2008) Amy Chan et al.   American Journal of Alzheimers Disease and Other Dementias

Epigenomic Profiling Reveals DNA-Methylation Changes Associated with Major Psychosis

(2008) Jonathan Mill et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Histone acetylation is not an accurate predictor of gene expression following treatment with histone deacetylase inhibitors

(2008) D.J.P. Ellis et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Transcriptional regulation of cholesterol 24-hydroxylase by histone deacetylase inhibitors

(2008) Marjan Shafaati et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Early-life events may trigger biochemical pathways for Alzheimer’s disease: the “LEARn” model

(2008) Debomoy K. Lahiri et al.   BIOGERONTOLOGY

Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders

(2008) T ABEL et al.   CURRENT OPINION IN PHARMACOLOGY

Improvement of aggressive behavior and quality of life impairment following S-Adenosyl-Methionine (SAM-e) augmentation in schizophrenia

(2008) Rael D. Strous et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Chromatin-modifying enzymes as therapeutic targets – Part 2

(2008) Brian R Keppler et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Chromatin-modifying enzymes as therapeutic targets – Part 1

(2008) Brian R Keppler et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Dysregulation of miRNA 181b in the temporal cortex in schizophrenia

(2008) Natalie J. Beveridge et al.   HUMAN MOLECULAR GENETICS

Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington’s disease

(2008) Judit Pallos et al.   HUMAN MOLECULAR GENETICS

Epigenetic therapy of leukemia: An update

(2008) Nitin Jain et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Histone deacetylase inhibitors up-regulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neurons

(2008) Xuefei Wu et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

High-Dose B Vitamin Supplementation and Cognitive Decline in Alzheimer Disease

(2008) Paul S. Aisen   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

MicroRNA-298 and MicroRNA-328 Regulate Expression of Mouse β-Amyloid Precursor Protein-converting Enzyme 1

(2008) Vincent Boissonneault et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Altered Histone Monoubiquitylation Mediated by Mutant Huntingtin Induces Transcriptional Dysregulation

(2008) M.-O. Kim et al.   JOURNAL OF NEUROSCIENCE

Alzheimer's Disease (AD)-Like Pathology in Aged Monkeys after Infantile Exposure to Environmental Metal Lead (Pb): Evidence for a Developmental Origin and Environmental Link for AD

(2008) J. Wu et al.   JOURNAL OF NEUROSCIENCE

The Expression of MicroRNA miR-107 Decreases Early in Alzheimer's Disease and May Accelerate Disease Progression through Regulation of  -Site Amyloid Precursor Protein-Cleaving Enzyme 1

(2008) W.-X. Wang et al.   JOURNAL OF NEUROSCIENCE

MicroRNAs can regulate human APP levels

(2008) Neha Patel et al.   Molecular Neurodegeneration

The Reelin and GAD67 Promoters Are Activated by Epigenetic Drugs That Facilitate the Disruption of Local Repressor Complexes

(2008) M. Kundakovic et al.   MOLECULAR PHARMACOLOGY

The current clinical management of Huntington's disease

(2008) Wendy Phillips et al.   MOVEMENT DISORDERS

A model for transmission of the H3K27me3 epigenetic mark

(2008) Klaus H. Hansen et al.   NATURE CELL BIOLOGY

Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of β-secretase

(2008) Mohammad Ali Faghihi et al.   NATURE MEDICINE

Sirtuins — novel therapeutic targets to treat age-associated diseases

(2008) Siva Lavu et al.   NATURE REVIEWS DRUG DISCOVERY

MicroRNA regulation of Alzheimer's Amyloid precursor protein expression

(2008) Sébastien S. Hébert et al.   NEUROBIOLOGY OF DISEASE

Symptomatic treatment of Huntington disease

(2008) Octavian R. Adam et al.   Neurotherapeutics

Age-Specific Epigenetic Drift in Late-Onset Alzheimer's Disease

(2008) Sun-Chong Wang et al.   PLoS One

Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/ -secretase expression

(2008) S. S. Hebert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation

(2008) E. Dong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice

(2008) E. A. Thomas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nicotine decreases DNA methyltransferase 1 expression and glutamic acid decarboxylase 67 promoter methylation in GABAergic interneurons

(2008) R. Satta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of the action of antipsychotic subtypes on valproate-induced chromatin remodeling

(2008) Alessandro Guidotti et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Chromosomal profiles of gene expression in Huntington's disease

(2007) A. N. Anderson et al.   BRAIN

The FE65 proteins and Alzheimer's disease

(2007) Declan M. McLoughlin et al.   JOURNAL OF NEUROSCIENCE RESEARCH

A microRNA-based gene dysregulation pathway in Huntington's disease

(2007) Rory Johnson et al.   NEUROBIOLOGY OF DISEASE

Histone deactylase 1 expression is increased in the prefrontal cortex of schizophrenia subjects: Analysis of the National Brain Databank microarray collection

(2007) Rajiv P. Sharma et al.   SCHIZOPHRENIA RESEARCH