Postprandial activation of metabolic and inflammatory signalling pathways in human peripheral mononuclear cells

PI3K/Akt contributes to increased expression of Toll-like receptor 4 in macrophages exposed to hypoxic stress

(2012) So Young Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Constitutive Akt1 signals attenuate B-cell receptor signaling and proliferation, but enhance B-cell migration and effector function

(2012) Mandy Pierau et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The dynamic range of the human metabolome revealed by challenges

(2012) Susanne Krug et al.   FASEB JOURNAL

Selective Inhibition of Phosphoinositide 3-Kinase p110α Preserves Lymphocyte Function

(2012) Lomon So et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anti-tumor necrosis factor therapy improves insulin resistance, beta cell function and insulin signaling in active rheumatoid arthritis patients with high insulin resistance

(2012) Ilias Stagakis et al.   ARTHRITIS RESEARCH & THERAPY

Antioxidant enzymes induced by repeated intake of excess energy in the form of high-fat, high-carbohydrate meals are not sufficient to block oxidative stress in healthy lean individuals

(2011) Sangbin Lim et al.   BRITISH JOURNAL OF NUTRITION

Akt Fine-tunes NF-κB-dependent Gene Expression during T Cell Activation

(2011) Jing Cheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intracellular molecular effects of insulin resistance in patients with metabolic syndrome

(2010) Evasio Pasini et al.   Cardiovascular Diabetology

Synergy in ERK activation by cytokine receptors and tyrosine kinase growth factor receptors

(2010) Xin Li et al.   CELLULAR SIGNALLING

Suppressive Effect of Insulin Infusion on Chemokines and Chemokine Receptors

(2010) H. Ghanim et al.   DIABETES CARE

Macronutrient intake induces oxidative and inflammatory stress: potential relevance to atherosclerosis and insulin resistance

(2010) Paresh Dandona et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Functional role of Akt in macrophage-mediated innate immunity

(2010) Yong Gyu Lee   Frontiers in Bioscience-Landmark

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Myeloid Cell-Restricted Insulin Receptor Deficiency Protects Against Obesity-Induced Inflammation and Systemic Insulin Resistance

(2010) Jan Mauer et al.   PLoS Genetics

Increase in Plasma Endotoxin Concentrations and the Expression of Toll-Like Receptors and Suppressor of Cytokine Signaling-3 in Mononuclear Cells After a High-Fat, High-Carbohydrate Meal: Implications for insulin resistance

(2009) H. Ghanim et al.   DIABETES CARE

The role of MMP-9 in integrin-mediated hippocampal cell death after pilocarpine-induced status epilepticus

(2009) Gyung W. Kim et al.   NEUROBIOLOGY OF DISEASE

S6K Directly Phosphorylates IRS-1 on Ser-270 to Promote Insulin Resistance in Response to TNF-α Signaling through IKK2

(2008) Jin Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CC Chemokine and CC Chemokine Receptor Profiles in Visceral and Subcutaneous Adipose Tissue Are Altered in Human Obesity

(2008) Joakim Huber et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival

(2008) Nancie J. MacIver et al.   JOURNAL OF LEUKOCYTE BIOLOGY