Mitogen-activated protein kinase mediates the apoptosis of highly metastatic human non-small cell lung cancer cells induced by isothiocyanates

Targeting the MAPK pathway in melanoma: Why some approaches succeed and other fail

(2010) Gajanan S. Inamdar et al.   BIOCHEMICAL PHARMACOLOGY

Isothiocyanates induce oxidative stress and suppress the metastasis potential of human non-small cell lung cancer cells

(2010) Xiang Wu et al.   BMC CANCER

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

(2010) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Benzyl Isothiocyanate (BITC) Inhibits Migration and Invasion of Human Colon Cancer HT29 Cells by Inhibiting Matrix Metalloproteinase-2/-9 and Urokinase Plasminogen (uPA) through PKC and MAPK Signaling Pathway

(2010) Kuang-Chi Lai et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Benzyl Isothiocyanate-Mediated Inhibition of Histone Deacetylase Leads to NF- B Turnoff in Human Pancreatic Carcinoma Cells

(2010) S. Batra et al.   MOLECULAR CANCER THERAPEUTICS

TNF receptor 2 pathway: drug target for autoimmune diseases

(2010) Denise Faustman et al.   NATURE REVIEWS DRUG DISCOVERY

Are isothiocyanates potential anti-cancer drugs?

(2009) Xiang Wu et al.   ACTA PHARMACOLOGICA SINICA

Implication of mitogen-activated protein kinase in the induction of G1 cell cycle arrest and gadd45 expression by the carotenoid fucoxanthin in human cancer cells

(2009) Yoshiko Satomi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Cruciferous Vegetable Consumption and Lung Cancer Risk: A Systematic Review

(2009) T. K. Lam et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Benzyl isothiocyanate-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of MAPK in human pancreatic cancer cells

(2009) Ravi P. Sahu et al.   CARCINOGENESIS

Cancer Preventive Isothiocyanates Induce Selective Degradation of Cellular α- and β-Tubulins by Proteasomes

(2009) Lixin Mi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Isothiocyanates sensitize the effect of chemotherapeutic drugs via modulation of protein kinase C and telomerase in cervical cancer cells

(2009) Sutapa Mukherjee et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Phenethyl isothiocyanate inhibits STAT3 activation in prostate cancer cells

(2009) Aiyu Gong et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21

(2009) Frederick J Sheedy et al.   NATURE IMMUNOLOGY

Modulation of markers associated with aggressive phenotype in MDA-MB-231 breast carcinoma cells by sulforaphane.

(2009) L. HUNAKOVA et al.   NEOPLASMA

Timosaponin AIII Is Preferentially Cytotoxic to Tumor Cells through Inhibition of mTOR and Induction of ER Stress

(2009) Frank W. King et al.   PLoS One

Effective elimination of fludarabine-resistant CLL cells by PEITC through a redox-mediated mechanism

(2008) D. Trachootham et al.   BLOOD

The Thioredoxin System Mediates Redox-Induced Cell Death in Human Colon Cancer Cells: Implications for the Mechanism of Action of Anticancer Agents

(2008) Y. Sun et al.   CANCER RESEARCH

Anti-NF-κB and anti-inflammatory activities of synthetic isothiocyanates: Effect of chemical structures and cellular signaling

(2008) Auemduan Prawan et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Benzyl isothiocyanate inhibits metalloproteinase-2/-9 expression by suppressing the mitogen-activated protein kinase in SK-Hep1 human hepatoma cells

(2008) Eun-Sun Hwang et al.   FOOD AND CHEMICAL TOXICOLOGY

Benzyl Isothiocyanate Targets Mitochondrial Respiratory Chain to Trigger Reactive Oxygen Species-dependent Apoptosis in Human Breast Cancer Cells

(2008) Dong Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY