Should myeloid and lymphoid neoplasms withPCM1-JAK2and other rearrangements ofJAK2be recognized as specific entities?

Hematologic malignancies with PCM1-JAK2 gene fusion share characteristics with myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, and FGFR1

(2013) Verena Patterer et al.   ANNALS OF HEMATOLOGY

A myeloproliferative neoplasm with translocation t(8;9)(p22;p24) involving JAK2 gene

(2013) N. Saba et al.   BLOOD

Implication of MAPK1/MAPK3 signalling pathway in t(8;9)(p22;24)/PCM1-JAK2myelodysplastic/myeloproliferative neoplasms

(2013) Elena Masselli et al.   BRITISH JOURNAL OF HAEMATOLOGY

Efficacy of Ruxolitinib in Chronic Eosinophilic Leukemia Associated With a PCM1-JAK2 Fusion Gene

(2013) Elisa Rumi et al.   JOURNAL OF CLINICAL ONCOLOGY

A BCR–JAK2 fusion gene from ins(22;9)(q11;p13p24) in a patient with atypical chronic myeloid leukemia

(2013) Yang Xu et al.   LEUKEMIA & LYMPHOMA

t(8;9)(p22;p24)/PCM1-JAK2 Activates SOCS2 and SOCS3 via STAT5

(2013) Stefan Ehrentraut et al.   PLoS One

Detection of ETV6 gene rearrangements in adult acute lymphoblastic leukemia

(2012) Min-hang Zhou et al.   ANNALS OF HEMATOLOGY

Ruxolitinib inhibits transforming JAK2 fusion proteins in vitro and induces complete cytogenetic remission in t(8;9)(p22;p24)/PCM1-JAK2-positive chronic eosinophilic leukemia

(2012) E. Lierman et al.   BLOOD

Genetic Alterations Activating Kinase and Cytokine Receptor Signaling in High-Risk Acute Lymphoblastic Leukemia

(2012) Kathryn G. Roberts et al.   CANCER CELL

Ruxolitinib as potential targeted therapy for patients with JAK2 rearrangements

(2012) A. Chase et al.   HAEMATOLOGICA

Chronic eosinophilic leukemia with erythroblastic proliferation and the rare translocation t(8;9)(p22;p24) withPCM1–JAK2fusion gene: a distinct clinical, pathological and genetic entity with potential treatment target?

(2012) Monika Prochorec-Sobieszek et al.   LEUKEMIA & LYMPHOMA

Transforming and Tumorigenic Activity of JAK2 by Fusion to BCR: Molecular Mechanisms of Action of a Novel BCR-JAK2 Tyrosine-Kinase

(2012) Álvaro Cuesta-Domínguez et al.   PLoS One

BCR-JAK2 fusion as a result of a translocation (9;22)(p24;q11.2) in a patient with CML-like myeloproliferative disease

(2012) Mohamed M Elnaggar et al.   Molecular Cytogenetics

Association ofJAK2Mutation Status and Cytogenetic Abnormalities in Myeloproliferative Neoplasms and Myelodysplastic/Myeloproliferative Neoplasms

(2011) Jennifer Dunlap et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

JAK2 rearrangements, including the novel SEC31A-JAK2 fusion, are recurrent in classical Hodgkin lymphoma

(2011) K. Van Roosbroeck et al.   BLOOD

Chromosomal translocation t(9;22)(p24;q11) appears to be recurrently associated with myeloid malignancy with aggressive course

(2011) Svetlana Angelova et al.   LEUKEMIA & LYMPHOMA

Two alternatively spliced 5′BCR/3′JAK2 fusion transcripts in a myeloproliferative neoplasm with a three-way t(9;18;22)(p23;p11.3;q11.2) translocation

(2011) Luciana Impera et al.   Cancer Genetics

Wide diversity of PAX5 alterations in B-ALL: a Groupe Francophone de Cytogenetique Hematologique study

(2010) E. Coyaud et al.   BLOOD

Pathology of the bone marrow and spleen in a case of myelodysplastic/myeloproliferative neoplasm associated with t(8;9)(p22;p24) involving PCM1 and JAK2 genes

(2010) Jean-Louis Dargent et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Chromosome 9p24 abnormalities: prevalence, description of novel JAK2 translocations, JAK2V617F mutation analysis and clinicopathologic correlates

(2010) Mrinal M. Patnaik et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

PCM1–JAK2-fusion: a potential treatment target in myelodysplastic–myeloproliferative and other hemato-lymphoid neoplasms

(2010) Sylvia Hoeller et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Novel JAK2 rearrangement resulting from a t(9;22)(p24;q11.2) in B-acute lymphoblastic leukemia

(2010) Carlos A. Tirado et al.   LEUKEMIA RESEARCH

Leukaemia cutis in atypical chronic myeloid leukaemia with a t(9;22) (p24;q11.2) leading to BCR-JAK2 fusion

(2008) Steven W. Lane et al.   BRITISH JOURNAL OF HAEMATOLOGY

A BCR-JAK2 fusion gene as the result of a t(9;22)(p24;q11) in a patient with acute myeloid leukemia

(2008) Gabriella Cirmena et al.   CANCER GENETICS AND CYTOGENETICS

NovelSSBP2-JAK2fusion gene resulting from a t(5;9)(q14.1;p24.1) in pre-B acute lymphocytic leukemia

(2008) Jennifer L. Poitras et al.   GENES CHROMOSOMES & CANCER

Evolutional change of karyotype with t(8;9)(p22;p24) and HLA-DR immunophenotype in relapsed acute myeloid leukemia

(2008) Kuan-Po Huang et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Incidence and diversity of PAX5 fusion genes in childhood acute lymphoblastic leukemia

(2008) K Nebral et al.   LEUKEMIA