An activin receptor IIA ligand trap promotes erythropoiesis resulting in a rapid induction of red blood cells and haemoglobin

Adult-Specific Systemic Over-Expression Reveals Novel In Vivo Effects of the Soluble Forms of ActRIIA, ActRIIB and BMPRII

(2013) Kengo Yamawaki et al.   PLoS One

Stromal cell-mediated inhibition of erythropoiesis can be attenuated by Sotatercept (ACE-011), an activin receptor type II ligand trap

(2012) Camelia Iancu-Rubin et al.   EXPERIMENTAL HEMATOLOGY

T Lymphocyte Potential Marks the Emergence of Definitive Hematopoietic Progenitors in Human Pluripotent Stem Cell Differentiation Cultures

(2012) Marion Kennedy et al.   Cell Reports

Stress erythropoiesis: new signals and new stress progenitor cells

(2011) Robert F Paulson et al.   CURRENT OPINION IN HEMATOLOGY

Emerging Roles for the Transforming Growth Factor-β Superfamily in Regulating Adiposity and Energy Expenditure

(2011) Nader Zamani et al.   ENDOCRINE REVIEWS

Erythropoiesis, anemia and the bone marrow microenvironment

(2011) Carl R. Walkley   INTERNATIONAL JOURNAL OF HEMATOLOGY

Erythropoietic and non-erythropoietic functions of erythropoietin in mouse models

(2011) Johannes Vogel et al.   JOURNAL OF PHYSIOLOGY-LONDON

Erythropoietin: A Hormone with Multiple Functions

(2011) Matilde Lombardero et al.   PATHOBIOLOGY

Temporal specification of blood progenitors from mouse embryonic stem cells and induced pluripotent stem cells

(2010) S. Irion et al.   DEVELOPMENT

Anemia, Ineffective Erythropoiesis, and Hepcidin: Interacting Factors in Abnormal Iron Metabolism Leading to Iron Overload in β-Thalassemia

(2010) Sara Gardenghi et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Hypoxia Regulates BMP4 Expression in the Murine Spleen during the Recovery from Acute Anemia

(2010) Dai-Chen Wu et al.   PLoS One

Extramedullary erythropoiesis in the adult liver requires BMP-4/Smad5–dependent signaling

(2009) Laurie E. Lenox et al.   EXPERIMENTAL HEMATOLOGY

Growth factor control of bone mass

(2009) Ernesto Canalis   JOURNAL OF CELLULAR BIOCHEMISTRY

Cell Lineages and the Logic of Proliferative Control

(2009) Arthur D Lander et al.   PLOS BIOLOGY

Development of stabilin2+ endothelial cells from mouse embryonic stem cells by inhibition of TGFβ/activin signaling

(2008) Hidenori Nonaka et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Wnt, Activin, and BMP Signaling Regulate Distinct Stages in the Developmental Pathway from Embryonic Stem Cells to Blood

(2008) M. Cristina Nostro et al.   Cell Stem Cell

The stepwise specification of embryonic stem cells to hematopoietic fate is driven by sequential exposure to Bmp4, activin A, bFGF and VEGF

(2008) S. Pearson et al.   DEVELOPMENT

Single-Dose, Randomized, Double-Blind, Placebo-Controlled Study of ACE-011 (ActRIIA-IgG1) in Postmenopausal Women*

(2008) Jon Ruckle et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Proteomic Identification and Functional Validation of Activins and Bone Morphogenetic Protein 11 as Candidate Novel Muscle Mass Regulators

(2008) Tatyana A. Souza et al.   MOLECULAR ENDOCRINOLOGY

A soluble activin Type IIA receptor induces bone formation and improves skeletal integrity

(2008) R. S. Pearsall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA