Genetic determinants of haemolysis in sickle cell anaemia

Genetic modifiers of sickle cell disease

(2012) Martin H. Steinberg et al.   AMERICAN JOURNAL OF HEMATOLOGY

Hemolysis and cell-free hemoglobin drive an intrinsic mechanism for human disease

(2012) Mark T. Gladwin et al.   JOURNAL OF CLINICAL INVESTIGATION

Nprl3 is required for normal development of the cardiovascular system

(2012) Monika S. Kowalczyk et al.   MAMMALIAN GENOME

A Genome-Wide Association Study of Total Bilirubin and Cholelithiasis Risk in Sickle Cell Anemia

(2012) Jacqueline N. Milton et al.   PLoS One

Systematic Localization of Common Disease-Associated Variation in Regulatory DNA

(2012) M. T. Maurano et al.   SCIENCE

Fetal hemoglobin in sickle cell anemia

(2011) I. Akinsheye et al.   BLOOD

Hospitalization for pain in patients with sickle cell disease treated with sildenafil for elevated TRV and low exercise capacity

(2011) R. F. Machado et al.   BLOOD

Reconstructing sickle cell disease: A data-based analysis of the “hyperhemolysis paradigm” for pulmonary hypertension from the perspective of evidence-based medicine

(2010) Robert P. Hebbel   AMERICAN JOURNAL OF HEMATOLOGY

Genome-wide association study of hematological and biochemical traits in a Japanese population

(2010) Yoichiro Kamatani et al.   NATURE GENETICS

Prospective Echocardiography Assessment of Pulmonary Hypertension and Its Potential Etiologies in Children With Sickle Cell Disease††Conflicts of interest: Dr. Gordeuk has received grants from BioMarin Pharmaceutical Inc., Novato, California, and Actelion Pharmaceuticals Ltd., Allschwil, Switzerland, and is a consultant for Ikaria Holdings, Clinton, New Jersey.

(2009) Niti Dham et al.   AMERICAN JOURNAL OF CARDIOLOGY

Relationship of erythropoietin, fetal hemoglobin, and hydroxyurea treatment to tricuspid regurgitation velocity in children with sickle cell disease

(2009) V. R. Gordeuk et al.   BLOOD

Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster

(2009) N. Solovieff et al.   BLOOD

Influence of the polymorphisms of the α-major regulatory element HS-40 on in vitro gene expression

(2009) D.M. Ribeiro et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

CTCF: Master Weaver of the Genome

(2009) Jennifer E. Phillips et al.   CELL

Elevated tricuspid regurgitant jet velocity in children and adolescents with sickle cell disease: association with hemolysis and hemoglobin oxygen desaturation

(2009) C. P. Minniti et al.   HAEMATOLOGICA

Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium

(2009) Santhi K Ganesh et al.   NATURE GENETICS

Chronic Hyper-Hemolysis in Sickle Cell Anemia: Association of Vascular Complications and Mortality with Less Frequent Vasoocclusive Pain

(2008) James G. Taylor et al.   PLoS One