Article
Dermatology
E. K. Johansson, A. Bergstrom, I Kull, E. Melen, M. Jonsson, S. Lundin, C-F Wahlgren, N. Ballardini
Summary: This Swedish study investigated the prevalence and characteristics of atopic dermatitis (AD) among young adults. The results showed that AD is a common disease among young adults, and even though more females than males have AD at 24 years, adult onset of AD seems to be equally prevalent among both sexes in young adulthood.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2022)
Article
Dermatology
Angelique N. Voorberg, Laura Loman, Marie L. A. Schuttelaar
Summary: There is limited data on chronic hand eczema and its severity in the general population. This cross-sectional study investigated the prevalence and severity of hand eczema in the Dutch population through a questionnaire. The results showed that the lifetime prevalence of hand eczema was 15.0%, the 1-year prevalence was 7.3%, and the self-reported physician-diagnosed prevalence was 6.1%. The study also found that the majority of subjects with hand eczema had almost clear symptoms at their worst, and the prevalence of severe to very severe hand eczema in the general population was 1.9%. The study suggests that future epidemiological research should include data on chronic hand eczema and its severity to gain a better understanding of the burden of hand eczema.
ACTA DERMATO-VENEREOLOGICA
(2022)
Review
Allergy
Anna S. Quaade, Anne B. Simonsen, Anne-Sofie Halling, Jacob P. Thyssen, Jeanne D. Johansen
Summary: Hand eczema (HE) is highly prevalent in the general population, with females being 1.5-2 times more likely to be affected than males. Over one third of patients suffer from moderate to severe disease, and around one third have a history of atopic dermatitis.
CONTACT DERMATITIS
(2021)
Review
Medicine, General & Internal
Cara Symanzik, Yasemin Topal Yueksel, Maria Oberlander Christensen, Jacob P. Thyssen, Christoph Skudlik, Swen Malte John, Richard Brans, Tove Agner
Summary: This study aims to compile and evaluate evidence regarding the prevalence and incidence of occupational hand eczema (HE) in healthcare workers (HCWs). By conducting systematic searches and analysis of published studies, the study will provide insights into the situation and severity of HE among HCWs.
Article
Medicine, General & Internal
Agnieszka Polecka, Andrzej Awchimkow, Natalia Owsianko, Anna Baran, Justyna Magdalena Hermanowicz, Iwona Flisiak
Summary: This study investigated the prevalence of hand eczema in the Polish female population and its association with disinfectant usage during the COVID-19 pandemic. The study found that hand eczema was more prevalent in younger adults, and increased disinfectant usage exacerbated the symptoms. Respondents with a dermatological history were more susceptible to new skin symptoms during the pandemic, and quality of life was significantly impacted.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Dermatology
K. M. A. Endre, L. Landro, M. LeBlanc, P. Gjersvik, K. C. Lodrup Carlsen, G. Haugen, G. Hedlin, C. M. Jonassen, B. Nordlund, K. Rudi, H. O. Skjerven, A. C. Staff, C. Soderhall, R. Vettukattil, E. M. Rehbinder
Summary: Diagnosing atopic dermatitis (AD) in infants is challenging, the study found that using the UK Working Party (UKWP) and Hanifin and Rajka (H&R) criteria can determine the incidence and persistence of eczema and AD. The odds of AD were lower when eczema first appeared at 6 or 12 months, and higher in infants with eczema at multiple visits.
BRITISH JOURNAL OF DERMATOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Chiara Celine Bruck, Frank J. Wolters, M. Arfan Ikram, Inge M. C. M. de Kok
Summary: Accurate projections of future dementia burden are important for healthcare systems and policymakers. Using a dementia microsimulation model, we found that changes in age-specific dementia incidence have a significant impact on the future burden of dementia.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Dermatology
L. von Kobyletzki, N. Ballardini, D. Henrohn, M. P. Neary, G. Ortsater, K. Geale, A. Rieem Dun, I. Lindberg, A. De Geer, P. Neregard, A. Cha, J. C. Cappelleri, W. Romero, J. P. Thyssen
Summary: This study describes the longitudinal care pathways of patients with atopic dermatitis (AD), including healthcare management, treatment patterns, and disease progression. The results show that healthcare contacts and AD treatments are concentrated in the year when managed AD care is initiated and decrease significantly thereafter. This suggests that patients with AD may be undertreated and monitored infrequently.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2022)
Article
Allergy
Anne Birgitte Simonsen, Jojo Biel-Nielsen Dietz, Jeanne Duus Johansen
Summary: This study aimed to explore the epidemiology, aetiology and severity of hand eczema (HE) among Danish adolescents. The study found a high prevalence of HE among Danish adolescents, raising concerns about this significant clinical problem.
CONTACT DERMATITIS
(2023)
Article
Medicine, General & Internal
Rola Hamood, Matanya Tirosh, Noga Fallach, Gabriel Chodick, Elon Eisenberg, Omri Lubovsky
Summary: This study explored the prevalence, incidence, correlations, and temporal trends of osteoarthritis (OA) in Israel from 2013 to 2018. It found that OA prevalence was higher in the Southern and Northern peripheral districts, and the incidence increased over time. Further population-based studies in the Middle East are needed to identify modifiable risk factors for timely preventive and therapeutic interventions in OA.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Allergy
Martin S. Havmose, Sanja Kezic, Wolfgang Uter, Cara Symanzik, Sarah Hallmann, Julia Strahwald, Patricia Weinert, Marija Macan, Rajka Turk, Henk F. van der Molen, Zeljka Babic, Jelena Macan, Swen M. John, Jeanne D. Johansen
Summary: Hairdressers are commonly affected by hand eczema due to hazardous exposure in the work environment. The prevalence of hand eczema is high among hairdressers, and occupational exposures play a major role. The incidence of atopic dermatitis is comparable to the general population. Preventive measures are needed to address hand eczema in hairdressers.
CONTACT DERMATITIS
(2022)
Article
Critical Care Medicine
Sadia Haider, Sara Fontanella, Anhar Ullah, Stephen Tumer, Angela Simpson, Graham Roberts, Clare S. Murray, John W. Holloway, John A. Curtin, Paul Cullinan, Syed Hasan Arshad, Guillem Hurault, Raquel Granell, Adnan Custovic
Summary: The study found significant variation in the patterns of eczema, wheeze, and rhinitis morbidity, with multimorbidity being rare but significantly overrepresented. Infantile eczema was associated with subsequent multimorbidity, but the majority of children with eczema did not progress to any comorbidities.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2022)
Article
Environmental Sciences
Xue-Ning Li, Dan Wu, Ying Liu, Shuang-Shuang Zhang, Fu-Lin Tian, Qi Sun, Wei Wei, Xia Cao, Li-Hong Jia
Summary: Research suggests that high levels of BPA exposure during pregnancy can increase the risk of infantile eczema, potentially due to the down-regulation of FOXP3 gene expression in cord blood.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Review
Dermatology
Wasim Jamil, Ake Svensson, Anna Josefson, Magnus Lindberg, Laura B. von Kobyletzki
Summary: This study systematically reviewed and assessed the association between occupational exposure and the incidence rate of hand eczema. Hairdressers, nurses, and metal workers had a higher risk of hand eczema, while even office workers, with low irritant exposure, were at risk of developing the condition.
ACTA DERMATO-VENEREOLOGICA
(2022)
Article
Dermatology
Jonathan I. Silverberg, Brenda Simpson, Katrina Abuabara, Emma Guttman-Yassky, Brian Calimlim, Colleen Wegzyn, Whitney Krueger, Amy Gamelli, Breda Munoz, Rachel W. Faller, Julie M. Crawford, Ayman Grada, Lawrence F. Eichenfield
Summary: This study aimed to assess the prevalence and quality of life impact of head/face/neck/hand (HFNH) involvement in patients with moderate-to-severe atopic dermatitis. The results showed that patients with HFNH involvement had worse quality of life and higher disease severity compared to those without HFNH involvement. Therefore, detailed assessments of specific areas affected by atopic dermatitis are needed for personalized treatment.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
(2023)
Article
Allergy
Niki Mitselou, Niklas Andersson, Anna Bergstrom, Inger Kull, Antonios Georgelis, Marianne van Hage, Anna M. Hedman, Catarina Almqvist, Jonas F. Ludvigsson, Erik Melen
Summary: The study found an inverse association between preterm birth and long-term IgE sensitization to common food and inhalant allergens. No relation was found between post-term birth and IgE sensitization. Replication analyses showed similar risk estimates for sensitization in a meta-analysis.
Article
Allergy
Emmanouela Sdona, Sandra Ekstrom, Niklas Andersson, Jenny Hallberg, Susanne Rautiainen, Niclas Hakansson, Alicja Wolk, Inger Kull, Erik Melen, Anna Bergstrom
Summary: A Swedish study found that higher fruit intake at age 8 was associated with reduced asthma risk and improved lung function, while vegetable intake showed no significant association. Additionally, higher antioxidant intake at age 8 was linked to reduced asthma risk and improved lung function, especially in males and participants sensitized to aeroallergens.
CLINICAL AND EXPERIMENTAL ALLERGY
(2022)
Article
Allergy
Elin Dahlen, Anna Bergstrom, Maria Odling, Sandra Ekstrom, Erik Melen, Inger Kull
Summary: The study found that young adults with asthma had low dispensing of asthma medication, with relatively low adherence to controller medication and some patients only being prescribed short-acting beta(2)-agonists. Additionally, adherence to controller medication was higher among those diagnosed in specialized care.
Article
Allergy
Anneli Julander, Emelie Rietz Liljedahl, Helena Korres de Paula, Eva Assarsson, Malin Engfeldt, Margareta Littorin, Christine Shobana Anto, Carola Liden, Karin Broberg
Summary: This study investigated the association between FLG gene status and nickel penetration, revealing that individuals carrying FLG null mutation had higher nickel penetration into the stratum corneum. Further studies are needed to confirm these findings.
CONTACT DERMATITIS
(2022)
Article
Environmental Sciences
Shanzina Iasmin Sompa, Anna Zettergren, Sandra Ekstrom, Swapna Upadhyay, Koustav Ganguly, Antonios Georgelis, Petter Ljungman, Goran Pershagen, Inger Kull, Erik Melen, Lena Palmberg, Anna Bergstrom
Summary: Despite the growing popularity of e-cigarettes, limited epidemiological studies have been conducted to investigate their impact on respiratory health in young adults. This study found that e-cigarette use was more common in male smokers and was associated with an increased risk of respiratory symptoms and overweight/obesity. However, the small number of exclusive e-cigarette users hindered firm conclusions.
ENVIRONMENTAL RESEARCH
(2022)
Review
Allergy
Carola Liden, Niklas Andersson, Ian R. White
Summary: The widespread use of skin sensitizing preservatives is well-known, but their use in non-cosmetic products is less recognized. This study reviewed EU legislations and analyzed data trends to find that the use of preservatives has significantly increased, posing a risk to health. Urgent action is needed to protect public health.
CONTACT DERMATITIS
(2022)
Letter
Allergy
Ida Mogensen, Charlotta Flodstrom, Anna Nopp, Erik Melen, Anna Bergstrom, Inger Kull
Article
Allergy
Sandra G. Tedner, Susanna Klevebro, Anna Bergstrom, Inger Kull, Niklas Andersson, Magnus P. Borres, Natalia Ballardini, Marit Westman, Jon R. Konradsen, Marianne van Hage, Caroline Nilsson, Erik Melen, Anna Asarnoj
Summary: This study found that sensitization to peanut extract after the age of 4 is mainly caused by cross-sensitization to birch, and IgE sensitization to Ara h 2 rarely occurs after the age of 8. Storage protein sensitization is associated with respiratory and systemic inflammation.
Article
Allergy
Emmanouela Sdona, Sandra Ekstrom, Niklas Andersson, Niclas Hakansson, Alicja Wolk, Marit Westman, Marianne van Hage, Inger Kull, Erik Melen, Anna Bergstrom
Summary: This study investigated the association between fibre intake and asthma, allergic rhinitis, and IgE sensitization. The results showed that higher fibre intake in childhood may be inversely associated with allergic rhinitis and sensitization to specific allergens up to adulthood. However, avoiding food triggers in allergic rhinitis patients may contribute to these protective associations.
CLINICAL AND TRANSLATIONAL ALLERGY
(2022)
Article
Dermatology
Klara Midander, Paulina Werner, Marlene Isaksson, Lukas Wisgrill, Carola Liden, Nanna Fyhrquist, Anneli Julander
Summary: In our study, we demonstrate that cobalt nanoparticles (CoNPs) have the potential to cause elicitation responses in cobalt sensitized individuals, manifesting in ACD lesions upon patch testing. Analysis of selected gene expression markers reveal identical immunological involvement in response to CoNP and CoCl2, suggesting that cobalt may cause elicitation reactions irrespective of its form at exposure. Finally, our results suggest that when exposed to CoNP, lower doses of Co are needed to elicit the same immunological response compared to when testing with CoCl2.
BRITISH JOURNAL OF DERMATOLOGY
(2023)
Article
Allergy
Helena Agenaes, Anna Lena Brorsson, Inger Kull, Anna Lindholm-Olinder
Summary: This study aimed to evaluate the effect of pollen subcutaneous immunotherapy (SCIT) on health-related quality of life (HRQoL) in children and adolescents with allergic rhinoconjunctivitis. The study found that after one year of pollen SCIT, HRQoL significantly improved, symptoms decreased, and the improvement was maintained during the study period. The proportion of severe and very severe symptoms also significantly decreased.
ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY
(2023)
Letter
Allergy
Sophia Bjoerkander, Paul Maier, Maura Kere, Simon Kebede Merid, Lorenz Wirth, Whitney Wiegel, Sandra Ekstroem, Inger Kull, Anna Bergstroem, Erik Melen, Jenny Mjoesberg, Christopher Andrew Tibbitt
Letter
Allergy
Malin Glindvad Ahlstrom, Michael Wennervaldt, Gregor McCombie, Pia Blaser, Carola Liden
CONTACT DERMATITIS
(2023)
Article
Allergy
Magnus Lindqvist, Katja Biering Leth-Moller, Allan Linneberg, Inger Kull, Anna Bergstrom, Antonios Georgellis, Magnus P. Borres, Agneta Ekebom, Marianne van Hage, Erik Melen, Marit Westman
Summary: Patients with pollen-induced allergic rhinitis face a high risk of persistent disease for at least 20 years, with childhood to adolescence being the most critical period for disease progression. The study findings underscore the close relationship between sensitization, allergic rhinitis, and asthma.
Article
Allergy
M. B. Gea Kiewiet, Christian Lupinek, Susanne Vrtala, Sandra Wieser, Alexandra Baar, Renata Kiss, Inger Kull, Erik Melen, Magnus Wickman, Daniela Porta, Davide Gori, Ulrike Gehring, Rob Aalberse, Jordi Sunyer, Marie Standl, Joachim Heinrich, Dagmar Waiblinger, John Wright, Josep M. Anto, Jean Bousquet, Marianne van Hage, Rudolf Valenta
Summary: The study analyzed the IgE sensitization profiles in more than 2800 children from different regions of Europe and found regional, exposome- and climate-dependent differences in molecular IgE-reactivity profiles. These findings provide the basis for precision medicine-based approaches for allergy treatment and prevention.
