Article
Oncology
Gabriele Nagel, Tone Bjorge, Andrea Jaensch, Raphael S. Peter, Christel Haggstrom, Alois Lang, Anders Engeland, Stanley Teleka, Karin Jirstrom, David Lindquist, Par Stattin, Hanno Ulmer, Hans Concin, Tanja Stocks
Summary: This study suggests that elevated triglycerides and interactions between metabolic factors may increase the risk of small intestine cancer among women. No significant associations were observed among men.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Article
Biochemistry & Molecular Biology
Maria J. Corbi-Cobo-Losey, Miguel A. Martinez-Gonzalez, Anne K. Gribble, Alejandro Fernandez-Montero, Adela M. Navarro, Ligia J. Dominguez, Maira Bes-Rastrollo, Estefania Toledo
Summary: This study investigated the association between coffee consumption and incident MetS. The findings suggest that moderate coffee consumption (1-4 cups per day) may be associated with a lower risk of developing MetS.
Article
Oncology
Maria J. Monroy-Iglesias, Beth Russell, Danielle Crawley, Naomi E. Allen, Ruth C. Travis, Aurora Perez-Cornago, Mieke Van Hemelrijck, Kerri Beckmann
Summary: The study found no significant association between Metabolic Syndrome (MetS) and risk of prostate cancer (PCa), but a consistent inverse association was observed with the blood sugar indicator HbA1c. Mediation analysis revealed potential hormonal and inflammatory pathways which may influence this association.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Article
Oncology
Henrik Ekedahl, Sigrid Isaksson, Olof Stahl, Karolina Bogefors, Patrik Romerius, Jakob Eberhard, Aleksander Giwercman
Summary: Low-grade inflammation is present in childhood cancer survivors and testicular cancer survivors. High levels of IL-6 are associated with hypogonadism and cardio-metabolic risk factors. Low levels of IL-10 may strengthen the risk of developing metabolic syndrome mediated by IL-6.
Article
Biochemistry & Molecular Biology
Anna Bartosiewicz, Edyta Luszczki, Malgorzata Nagorska, Lukasz Oleksy, Artur Stolarczyk, Katarzyna Deren
Summary: Metabolic syndrome is prevalent among nurses in Poland, with overweight and obesity being significant factors influencing its development. Preventive and supportive measures are necessary to address this issue.
Article
Oncology
Yaqian Liu, Caiwang Yan, Shuangshuang Yin, Tianpei Wang, Meng Zhu, Li Liu, Guangfu Jin
Summary: Metabolic syndrome and genetic factors may contribute jointly to the risk of gastrointestinal cancer, and quantitative measurements can be used to identify high-risk populations for precise prevention.
Article
Gastroenterology & Hepatology
Juan Carlos Rodriguez-Duque, Jose Luis Calleja, Paula Iruzubieta, Marta Hernandez-Conde, Coral Rivas-Rivas, Maria Isabel Vera, Maria Jose Garcia, Marta Pascual, Beatriz Castro, Agustin Garcia-Blanco, Enrique Garcia-Nieto, Soraya Curiel-del Olmo, Maria Luisa Cagigal, Lorena Lopez-Montejo, Tatiana Fernandez-Lamas, Laura Rasines, Jose Ignacio Fortea, Jose Pedro Vaque, Yza Frias, Montserrat Rivero, Maria Teresa Arias-Loste, Javier Crespo
Summary: This study investigated the prevalence and risk factors of metabolic-associated fatty liver disease (MAFLD) in patients with inflammatory bowel disease (IBD). The results showed that the prevalence of MAFLD and liver fibrosis was significantly higher in IBD patients compared to the general population, independent of traditional metabolic risk factors. This study is important for understanding the liver health of IBD patients.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Endocrinology & Metabolism
Yi Guo, Shiyun Luo, Yongxin Ye, Songping Yin, Jiahua Fan, Min Xia
Summary: This study examined the effects of intermittent fasting (IF) on cardiometabolic risk factors and gut microbiota in patients with metabolic syndrome (MS). IF resulted in significant reductions in fat mass, improved oxidative stress, modulated inflammatory cytokines, and altered gut microbiota communities. The changes induced by IF were associated with cardiovascular risk factors and led to distinct genetic shifts in carbohydrate metabolism within the gut microbiota community.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Medicine, General & Internal
Seonyoung Kang, Kyungdo Han, Jinhyoung Jung, Yeonghee Eun, In Young Kim, Eun-Mi Koh, Seulkee Lee, Hoon-Suk Cha, Hyungjin Kim, Jaejoon Lee
Summary: Hyperuricemia (HUA) is associated with metabolic syndrome (MetS) and cardiovascular disease (CVD), and there are sex-based differences in the relationships between HUA and its associated risk factors. This study aimed to investigate these differences and evaluate the joint effects of these factors based on sex.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Biochemistry & Molecular Biology
Emanuele Durante-Mangoni, Domenico Iossa, Valeria Iorio, Irene Mattucci, Umberto Malgeri, Daniela Pinto, Roberto Andini, Ciro Maiello, Rosa Zampino
Summary: Post-transplant diabetes mellitus (PTDM) is a common complication after heart transplant, sharing similarities with type 2 diabetes but also having specific causes. This study evaluated the incidence and risk factors of PTDM and studied its relationship with glucose metabolic alterations and heart transplant outcomes. The results showed that PTDM is closely related to BMI increase, metabolic syndrome development, and recipient survival.
Article
Endocrinology & Metabolism
Ahmed Torky, Ninet Sinaii, Smita Jha, Jay Desai, Diala El-Maouche, Ashwini Mallappa, Deborah P. Merke
Summary: Patients with CAH have a higher prevalence of obesity, hypertension, insulin resistance, fasting hyperglycemia, and dyslipidemia during childhood and adulthood compared to the general US population, indicating an early onset of metabolic morbidity in this population. Treatment-related and familial factors play a role in the development of these metabolic conditions.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Nutrition & Dietetics
Ting Tian, Yuanyuan Wang, Wei Xie, Jingxian Zhang, Yunlong Ni, Xianzhen Peng, Guiju Sun, Yue Dai, Yonglin Zhou
Summary: This study investigated the relationship between vitamin A and metabolic syndrome and other metabolic risk factors in children and adolescents. The findings suggest a positive association between vitamin A and obesity, metabolic syndrome, dyslipidemia, and hyperuricemia.
Article
Nutrition & Dietetics
Anna Kokkinopoulou, Niki Katsiki, Ioannis Pagkalos, Nikolaos E. Rodopaios, Alexandra-Aikaterini Koulouri, Eleni Vasara, Sousana K. Papadopoulou, Petros Skepastianos, Emmanouil Dermitzakis, Maria Hassapidou, Anthony G. Kafatos
Summary: This study investigated the effects of adherence to the periodic Christian Orthodox Church (COC) fasting on nutrient intake, body composition, and risk factors for metabolic syndrome (MetS). The results showed that individuals following the COC fasting had lower intake of calories, protein, fat, and cholesterol compared to non-fasters. Fasters also had a healthier lifestyle pattern and a lower risk for MetS. Further research is needed to determine the long-term clinical impact of these findings.
Review
Endocrinology & Metabolism
Ziyu Chen, Zesi Liu, Hongxia Yang, Chaosheng Liu, Fandou Kong
Summary: This study conducted a systematic review and meta-analysis to examine the association between metabolic syndrome (MetS) and ovarian cancer risk. The results showed no significant correlation between MetS and ovarian cancer risk. Only the unadjusted stratification of smoking and hysterectomy risk demonstrated a relationship between MetS and ovarian cancer risk.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Biology
Zhongjie Fu, Anders K. Nilsson, Ann Hellstrom, Lois E. H. Smith
Summary: Retinopathy of prematurity (ROP) is caused by the suppression of physiological retinal vascular development, leading to compensatory but pathological neovascularization. Promoting normal vessel growth can prevent ROP. Early perinatal metabolic dysregulation is a risk factor for ROP and other long-term sequelae. Controlling postnatal hyperglycemia, dyslipidemia, and hyperoxia can promote normal retinal development.
Article
Anesthesiology
Julia Hasslacher, Fabian Steinkohl, Hanno Ulmer, Georg Lehner, Sebastian Klein, Timo Mayerhoefer, Michael Joannidis
Summary: This study investigated the incidence, characteristics, and outcome of ventilator-associated pneumonia (VAP) in patients after cardiac arrest (CA) and its potential association with mild therapeutic hypothermia (MTH). The study found that VAP is a common complication in patients after CA, accompanied by more ventilator-dependent days, prolonged antibiotic treatment, and ICU-LOS. Treatment with MTH is significantly associated with the development of VAP.
ACTA ANAESTHESIOLOGICA SCANDINAVICA
(2022)
Article
Oncology
Sylvia H. J. Jochems, Christel Haggstrom, Par Stattin, Bengt Jarvholm, Tanja Stocks
Summary: This study found a slightly lower risk of prostate cancer development associated with increasing levels of systolic and diastolic blood pressure (BP). However, this association was limited to certain conditions and not consistent for more advanced disease at diagnosis. Additionally, prediagnostic BP was unlikely to be an important risk factor for prostate cancer development and death, with the lower risk observed among men with higher BP levels potentially explained by less asymptomatic PSA testing.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2022)
Article
Infectious Diseases
Miriam A. Knoll, Nina Lackner, Hanno Ulmer, Eldina Samardzic, Joerg Steinmann, Robert Krause, Hedda L. Verhasselt, Peter-Michael Rath, Frieder Fuchs, Philipp Koehler, Blandine Denis, Samia Hamane, Alexandre Alanio, Cornelia Lass-Floerl
Summary: This study investigated the prevalence of multidrug resistance among different colonies in in vitro antifungal susceptibility testing (AFST) using a new method called multiple colony testing (MCT). The results suggest that single MIC values obtained in routine diagnostics may not accurately detect multidrug resistance and resistant subpopulations.
CLINICAL MICROBIOLOGY AND INFECTION
(2022)
Article
Clinical Neurology
Ettore Beghi, Raimund Helbok, Serefnur Ozturk, Omer Karadas, Vitalie Lisnic, Oxana Grosu, Tibor Kovacs, Levente Dobronyi, Daniel Bereczki, Maria Sofia Cotelli, Marinella Turla, Eugenia Irene Davidescu, Bogdan Ovidiu Popescu, Franco Valzania, Francesco Cavallieri, Hanno Ulmer, Luis F. Maia, Anne Hege Amodt, Carmel Armon, Waldemer Brola, Gryb Victoria, Anis Riahi, Ingomar Krehan, Tim Oertzen, Mohammed A. Azab, Michael Crean, Maria Lolich, Maria Joao Lima, Johann Sellner, Julian Perneczky, Tom Jenkins, Sara Meoni, Elisa Bianchi, Elena Moro, Claudio L. A. Bassetti
Summary: Despite increasing reports on neurological manifestations of COVID-19, few studies have assessed the short- and long-term outcomes of the disease. This cohort study found that neuro-COVID is a severe disease associated with worse functional status at discharge, particularly in older subjects and those with comorbidities and acute complications of infection.
EUROPEAN JOURNAL OF NEUROLOGY
(2022)
Article
Oncology
Ming Sun, Tone Bjorge, Stanley Teleka, Anders Engeland, Patrik Wennberg, Christel Haggstrom, Tanja Stocks
Summary: This study suggests that leisure-time physical activity is associated with a reduced risk of obesity-related cancer, both in normal weight and overweight individuals. High physical activity levels were found to significantly lower risks of various cancers, particularly when combined with a normal BMI.
INTERNATIONAL JOURNAL OF CANCER
(2022)
Article
Dentistry, Oral Surgery & Medicine
Lisa Schieffer, Lukas Latzko, Hanno Ulmer, Natalie Schenz-Spisic, Ulrike Lepperdinger, Magdalena Paulus, Adriano G. Crismani
Summary: This study aimed to assess the validity, reliability, reproducibility, and objectivity of measurements on stone casts compared to measurements on digital models in patients with mixed dentitions. The results showed significant intermethod differences for certain parameters, with only the differences in overbite and intermolar distance being clinically relevant. The digital measurements and those performed by the experienced examiner exhibited high intermethod reliability and lower measurement errors. Both the digital and analogue measurements were highly reproducible and reliable, although operator experience did impact the objectivity of the measurements.
JOURNAL OF OROFACIAL ORTHOPEDICS-FORTSCHRITTE DER KIEFERORTHOPADIE
(2022)
Article
Oncology
Stanley Teleka, Sylvia H. J. Jochems, Karin Jirstrom, Tanja Stocks
Summary: This study found that smoking combined with certain genetic risks increases the risk of UC. Individuals with the slow acetylation NAT2 variant may particularly benefit from smoking intervention to prevent lethal UC.
Article
Public, Environmental & Occupational Health
Michael Berktold, Stefan Fuchs, Bettina Kuppelwieser, Hanno Ulmer, Margareth Kettner, Lucas Thummer, Ewald Woell, Cornelia Lass-Floerl
Summary: This study used a questionnaire-based survey to assess the adherence of Tyrolean hospitals to the recommendations of the Centers for Disease Control and Prevention (CDC) for infection control. The results showed varying levels of adherence among different medical disciplines, with higher adherence among infection control specialists and lower adherence among clinical disciplines. The adherence between nurses and physicians was generally high.
AMERICAN JOURNAL OF INFECTION CONTROL
(2023)
Letter
Urology & Nephrology
Sylvia H. J. Jochems, Par Stattin, Tanja Stocks
Article
Oncology
Julie A. Schmidt, Inge Huybrechts, Kim Overvad, Anne Kirstine Eriksen, Anne Tjonneland, Rudolf Kaaks, Verena Katzke, Matthias B. Schulze, Valeria Pala, Carlotta Sacerdote, Rosario Tumino, Bas Bueno-de-Mesquita, Maria-Jose Sanchez, Jose M. Huerta, Aurelio Barricarte, Pilar Amiano, Antonio Agudo, Anders Bjartell, Tanja Stocks, Elin Thysell, Maria Wennberg, Elisabete Weiderpass, Ruth C. Travis, Timothy J. Key, Aurora Perez-Cornago
Summary: This study investigated the associations between dietary protein intake and prostate cancer risk and mortality. The results suggest that dairy protein and yogurt protein are positively associated with prostate cancer risk, while egg protein may be positively associated with prostate cancer mortality. However, considering the weak associations and many tests conducted, these results should be interpreted with caution.
Article
Oncology
Ming Sun, Josef Fritz, Christel Haggstrom, Tone Bjorge, Gabriele Nagel, Jonas Manjer, Anders Engeland, Emanuel Zitt, Bethany van Guelpen, Par Stattin, Hanno Ulmer, Tanja Stocks
Summary: This study investigates the relationship between obesity with or without metabolic aberrations and cancer risk, specifically obesity-related cancer. The study finds that metabolically unhealthy obesity is associated with an increased relative risk of various obesity-related cancers, while metabolically healthy obesity also increases the risk for certain cancers, although to a lesser extent. The study highlights the importance of considering the metabolic phenotype when assessing obesity-related cancer risk.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2023)
Article
Oncology
Magdalena A. Benda, Hanno Ulmer, Roman Weger, Patrick Reimann, Theresia Lang, Petra Pichler, Thomas Winder, Bernd Hartmann, Irene Strassl, Maria Theresa Krauth, Hermine Agis, Siegfried Sormann, Klaus Podar, Wolfgang Willenbacher, Ella Willenbacher
Summary: In this retrospective study, the attrition rate in the Austrian Myeloma Registry (AMR) was analyzed, and the results showed lower attrition rates compared to previous data, especially in elderly patients and those receiving optimal frontline treatment. The importance of achieving optimal treatment response was highlighted, not only in terms of attrition rates, but also in terms of treatment-free intervals. These promising results support the key role of liberal universal drug access and reimbursement.
Article
Oncology
Sylvia H. J. Jochems, Josef Fritz, Christel Haggstrom, Paer Stattin, Tanja Stocks
Summary: This study found no significant association between insulin resistance markers and the risk of prostate cancer. However, higher levels of glucose and triglyceride-glucose index were associated with higher prostate cancer mortality. Other insulin resistance markers did not show significant associations with prostate cancer mortality.
Article
Infectious Diseases
Lisa Seekircher, Zoltan Banki, Janine Kimpel, Annika Roessler, Helena Schaefer, Barbara Falkensammer, David Bante, Lukas Forer, Sebastian Schonherr, Teresa Harthaller, Magdalena Sacher, Cornelia Ower, Lena Tschiderer, Hanno Ulmer, Florian Krammer, Dorothee von Laer, Wegene Borena, Peter Willeit
Summary: This study investigated the associations between antibody and T-cell responses after COVID-19 vaccination and the risk of SARS-CoV-2 breakthrough infection, as well as whether measurement of these responses enhances risk prediction.
Article
Cardiac & Cardiovascular Systems
Leo Poelzl, Clemens Engler, Philipp Sterzinger, Ronja Lohmann, Felix Naegele, Jakob Hirsch, Michael Graber, Jonas Eder, Sebastian Reinstadler, Nikolay Sappler, Juliane Kilo, Ivan Tancevski, Sebastian Bachmann, Hannes Abfalterer, Elfriede Ruttmann-Ulmer, Hanno Ulmer, Andrea Griesmacher, Samuel Heuts, Matthias Thielmann, Axel Bauer, Michael Grimm, Nikolaos Bonaros, Johannes Holfeld, Can Gollmann-Tepekoeylue
Summary: This study found that high postoperative levels of hs-cTnT are associated with increased 30-day mortality, but not with 5-year mortality. The hs-cTnT thresholds for mortality-associated PMI in different cardiac surgeries were higher than currently suggested.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
