Mutations in AEC syndrome skin reveal a role for p63 in basement membrane adhesion, skin barrier integrity and hair follicle biology

p63, a Story of Mice and Men

(2011) Hans Vanbokhoven et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

p63in Epithelial Survival, Germ Cell Surveillance, and Neoplasia

(2010) Christopher P. Crum et al.   Annual Review of Pathology-Mechanisms of Disease

Rapp-Hodgkin and Hay-Wells ectodermal dysplasia syndromes represent a variable spectrum of the same genetic disorder

(2010) S.E. Clements et al.   BRITISH JOURNAL OF DERMATOLOGY

Abnormal hair follicle development and altered cell fate of follicular keratinocytes in transgenic mice expressing  Np63 

(2010) R. A. Romano et al.   DEVELOPMENT

SAM as a protein interaction domain involved in developmental regulation

(2010) Jörg Schultz et al.   PROTEIN SCIENCE

ΔNp63 knockdown mice: A mouse model for AEC syndrome

(2009) Maranke I. Koster et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Pathologic changes of skin and hair in ankyloblepharon-ectodermal defects-cleft lip/palate (AEC) syndrome

(2009) Megan K. Dishop et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

p63 directly induces expression of Alox12, a regulator of epidermal barrier formation

(2009) Soeun Kim et al.   EXPERIMENTAL DERMATOLOGY

Identification and functional characterization of two new transcriptional variants of the human p63 gene

(2009) Marina Mangiulli et al.   NUCLEIC ACIDS RESEARCH

Transcriptional Network of p63 in Human Keratinocytes

(2009) Silvia Pozzi et al.   PLoS One

An Active Role of the ΔN Isoform of p63 in Regulating Basal Keratin Genes K5 and K14 and Directing Epidermal Cell Fate

(2009) Rose-Anne Romano et al.   PLoS One

New concepts on the histogenesis of eccrine neoplasia from keratin expression in the normal eccrine gland, syringoma and poroma

(2008) L. Langbein et al.   BRITISH JOURNAL OF DERMATOLOGY

P-cadherin is a p63 target gene with a crucial role in the developing human limb bud and hair follicle

(2008) Y. Shimomura et al.   DEVELOPMENT

Direct targets of the TRP63 transcription factor revealed by a combination of gene expression profiling and reverse engineering

(2008) G. Della Gatta et al.   GENOME RESEARCH

A novel translation re-initiation mechanism for the p63 gene revealed by amino-terminal truncating mutations in Rapp-Hodgkin/Hay-Wells-like syndromes

(2008) T. Rinne et al.   HUMAN MOLECULAR GENETICS

IKKα Is a p63 Transcriptional Target Involved in the Pathogenesis of Ectodermal Dysplasias

(2008) Barbara Marinari et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Antimicrobial Protein Psoriasin (S100A7) Is Upregulated in Atopic Dermatitis and after Experimental Skin Barrier Disruption

(2008) Regine Gläser et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The classification of inherited epidermolysis bullosa (EB): Report of the Third International Consensus Meeting on Diagnosis and Classification of EB

(2008) Jo-David Fine et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Claudin-1 Is a p63 Target Gene with a Crucial Role in Epithelial Development

(2008) Teresa Lopardo et al.   PLoS One