Improved prediction of tacrolimus concentrations early after kidney transplantation using theory-based pharmacokinetic modelling

Tacrolimus Predose Concentrations Do Not Predict the Risk of Acute Rejection After Renal Transplantation: A Pooled Analysis From Three Randomized-Controlled Clinical Trials†

(2013) R. Bouamar et al.   AMERICAN JOURNAL OF TRANSPLANTATION

A published pharmacogenetic algorithm was poorly predictive of tacrolimus clearance in an independent cohort of renal transplant recipients

(2013) Oliver Boughton et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Clinical implementation of pharmacogenetics in kidney transplantation: calcineurin inhibitors in the starting blocks

(2013) Laure Elens et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Busulfan in Infant to Adult Hematopoietic Cell Transplant Recipients: A Population Pharmacokinetic Model for Initial and Bayesian Dose Personalization

(2013) Jeannine S. McCune et al.   CLINICAL CANCER RESEARCH

Importance of hematocrit for a tacrolimus target concentration strategy

(2013) Elisabet Størset et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Lessons From Routine Dose Adjustment of Tacrolimus in Renal Transplant Patients Based on Global Exposure

(2013) Franck Saint-Marcoux et al.   THERAPEUTIC DRUG MONITORING

Integration of data from multiple sources for simultaneous modelling analysis: experience from nevirapine population pharmacokinetics

(2012) Elin Svensson et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

TheCYP3A4*22allele affects the predictive value of a pharmacogenetic algorithm predicting tacrolimus predose concentrations

(2012) Laure Elens et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Prediction of the tacrolimus population pharmacokinetic parameters according to CYP3A5 genotype and clinical factors using NONMEM in adult kidney transplant recipients

(2012) Nayoung Han et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Safe and Effective Variability—A Criterion for Dose Individualization

(2012) Nicholas H.G. Holford et al.   THERAPEUTIC DRUG MONITORING

Interpreting Tacrolimus Concentrations During Pregnancy and Postpartum

(2012) Mary F. Hebert et al.   TRANSPLANTATION

Prediction-Corrected Visual Predictive Checks for Diagnosing Nonlinear Mixed-Effects Models

(2011) Martin Bergstrand et al.   AAPS Journal

Dosing equation for tacrolimus using genetic variants and clinical factors

(2011) Chaitali Passey et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Maximum A Posteriori Bayesian Estimation of Mycophenolic Acid Area Under the Concentration-Time Curve: Is This Clinically Useful for Dosage Prediction Yet?

(2011) Christine E. Staatz et al.   CLINICAL PHARMACOKINETICS

Prediction tacrolimus blood levels based on the Bayesian method in adult kidney transplant patients

(2011) Marie Antignac et al.   EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS

Therapeutic drug monitoring of tacrolimus by liquid chromatography–tandem mass spectrometry: Is it truly a routine test?

(2011) Paul J. Taylor et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

A Simultaneous D-Optimal Designed Study for Population Pharmacokinetic Analyses of Mycophenolic Acid and Tacrolimus Early After Renal Transplantation

(2011) Flora Tshinanu Musuamba et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Evaluation of limited sampling methods for estimation of tacrolimus exposure in adult kidney transplant recipients

(2010) Katherine A. Barraclough et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Population pharmacokinetic model and Bayesian estimator for two tacrolimus formulations - twice daily Prograf® and once daily Advagraf®

(2010) Jean-Baptiste Woillard et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Effect of CYP3A and ABCB1 Single Nucleotide Polymorphisms on the Pharmacokinetics and Pharmacodynamics of Calcineurin Inhibitors: Part I

(2010) Christine E. Staatz et al.   CLINICAL PHARMACOKINETICS

Determination of cyclosporine, tacrolimus, sirolimus and everolimus by liquid chromatography coupled to electrospray ionization and tandem mass spectrometry: Assessment of matrix effects and assay performance

(2010) Nils T. Vethe et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION

Importance of Shrinkage in Empirical Bayes Estimates for Diagnostics: Problems and Solutions

(2009) Radojka M. Savic et al.   AAPS Journal

Tacrolimus Population Pharmacokinetic-Pharmacogenetic Analysis and Bayesian Estimation in Renal Transplant Recipients

(2009) Khaled Benkali et al.   CLINICAL PHARMACOKINETICS

Mechanistic Basis of Using Body Size and Maturation to Predict Clearance in Humans

(2009) Brian J. Anderson et al.   Drug Metabolism and Pharmacokinetics

Opportunities to Optimize Tacrolimus Therapy in Solid Organ Transplantation: Report of the European Consensus Conference

(2009) Pierre Wallemacq et al.   THERAPEUTIC DRUG MONITORING

Explaining Variability in Tacrolimus Pharmacokinetics to Optimize Early Exposure in Adult Kidney Transplant Recipients

(2009) Rogier R Press et al.   THERAPEUTIC DRUG MONITORING

Multi-site Analytical Evaluation of the Abbott ARCHITECT Tacrolimus Assay

(2009) Pierre Wallemacq et al.   THERAPEUTIC DRUG MONITORING

The Challenge of Achieving Target Drug Concentrations in Clinical Trials: Experience From the Symphony Study

(2009) Henrik Ekberg et al.   TRANSPLANTATION

Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling in translational drug research

(2008) M DANHOF et al.   TRENDS IN PHARMACOLOGICAL SCIENCES