Paediatric drug development: are population models predictive of pharmacokinetics across paediatric populations?

Pharmacokinetic study of once-daily versus twice-daily abacavir and lamivudine in HIV type-1-infected children aged 3-

(2010)   ANTIVIRAL THERAPY

A Model-Based Approach to Dose Selection in Early Pediatric Development

(2010) M Cella et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

What is the right dose for children?

(2009) Massimo Cella et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

From Trial and Error to Trial Simulation. Part 2: An Appraisal of Current Beliefs in the Design and Analysis of Clinical Trials for Antidepressant Drugs

(2009) G Santen et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Drug therapy in pediatrics: a developing field

(2009) Lisa Mathis et al.   Dermatologic Therapy

Intravenous Paracetamol (Acetaminophen)

(2009) Sean T. Duggan et al.   DRUGS

Pharmacokinetics and dosage adjustment in patients with renal dysfunction

(2009) Roger K. Verbeeck et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Treatment of congenital cytomegalovirus infection: implications for future therapeutic strategies

(2009) L. Nassetta et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Comparative juvenile safety testing of new therapeutic candidates: Relevance of laboratory animal data to children

(2009) Tim Anderson et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Essentials for starting a pediatric clinical study (1): Pharmacokinetics in children

(2009) Tsuyoshi Yokoi   JOURNAL OF TOXICOLOGICAL SCIENCES

Computing normalised prediction distribution errors to evaluate nonlinear mixed-effect models: The npde add-on package for R

(2008) Emmanuelle Comets et al.   COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

HLA-B*5701 Screening for Hypersensitivity to Abacavir

(2008) Simon Mallal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mechanism-Based Concepts of Size and Maturity in Pharmacokinetics

(2007) B.J. Anderson et al.   Annual Review of Pharmacology and Toxicology