Article
Oncology
Fei Chen, Sungshim L. Park, Lynne R. Wilkens, Peggy Wan, Steven N. Hart, Chunling Hu, Siddhartha Yadav, Fergus J. Couch, David V. Conti, Adam J. de Smith, Christopher A. Haiman
Summary: This multiethnic study found that germline pathogenic variants in BRCA1, BRCA2, and ERCC2 are associated with the development of second primary cancer in breast cancer survivors, providing biological insights and biomarkers for patient monitoring.
Article
Oncology
Sara J. Schonfeld, Ruth A. Kleinerman, David H. Abramson, Johanna M. Seddon, Margaret A. Tucker, Lindsay M. Morton
Summary: Hereditary retinoblastoma survivors have significantly increased risk of second malignant neoplasms, especially sarcomas and melanomas, while nonhereditary retinoblastoma survivors have lower recurrence risks.
BRITISH JOURNAL OF CANCER
(2021)
Article
Chemistry, Medicinal
Leah L. Lowder, Matthew Powell, Sean E. Miller, Rigel J. Kishton, Charles B. Kelly, Connor B. Cribb, Kelly Mastro-Kishton, Manoj Chelvanambi, Phat T. Do, Rajeshwar Reddy Govindapur, Suzanne E. Wardell, Donald P. McDonnell, Libero J. Bartolotti, Giridhar R. Akkaraju, Arthur R. Frampton, Sridhar Varadarajan
Summary: DNA-alkylating compounds selectively target breast cancer cells by facilitating ERα translocation to the nucleus and inducing ERα target gene expression; minor structural changes significantly impact DNA binding and methylating abilities of the compounds; this approach may overcome limitations of current chemotherapy agents.
JOURNAL OF MEDICINAL CHEMISTRY
(2021)
Review
Oncology
Marco Torella, Gaetano Riemma, Pasquale De Franciscis, Marco La Verde, Nicola Colacurci
Summary: Innovations in childhood cancer treatment have increased survival rates, but female childhood cancer survivors are at risk for late reproductive aftereffects. AMH is used for ovarian reserve screening in reproductive medicine, but is not the gold standard. This study found that female neuroblastoma survivors have higher risk for reduced AMH levels and POI.
Article
Oncology
Rodrigue S. Allodji, Margaret A. Tucker, Michael M. Hawkins, Marie-Cecile Le Deley, Cristina Veres, Rita Weathers, Rebecca Howell, Dave Winter, Nadia Haddy, Carole Rubino, Ibrahima Diallo, Mark P. Little, Lindsay M. Morton, Florent de Vathaire
Summary: Childhood cancer survivors are at increased risk for second primary leukemia (SPL), with topoisomerase II inhibitors and radiation dose to active bone marrow being identified as risk factors. SPL is most likely to occur in the first decade following cancer treatment.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Review
Biochemistry & Molecular Biology
Giampiero Ferraguti, Sergio Terracina, Carla Petrella, Antonio Greco, Antonio Minni, Marco Lucarelli, Enzo Agostinelli, Massimo Ralli, Marco de Vincentiis, Giammarco Raponi, Antonella Polimeni, Mauro Ceccanti, Brunella Caronti, Maria Grazia Di Certo, Christian Barbato, Alessandro Mattia, Luigi Tarani, Marco Fiore
Summary: Head and neck cancer (HNC) is a disease that affects more than 890,000 patients worldwide annually and is associated with advanced stage and severe outcomes. Alcohol consumption, tobacco smoking, and human papillomavirus infection are the main risk factors. This article discusses the mechanisms of alcohol in HNC and suggests prevention strategies, such as polyphenol supplements and alkylating drugs.
Review
Oncology
Zhenkun Fu, Zhoujun Lin, Mao Yang, Chenggang Li
Summary: Breast cancer is a common type of cancer, with surgery being the preferred treatment method. Various adjuvant therapies such as radiotherapy, chemotherapy, endocrine therapy, and targeted drug therapy can also be used.
FRONTIERS IN ONCOLOGY
(2022)
Article
Oncology
Tara O. Henderson, Qi Liu, Lucie M. Turcotte, Joseph P. Neglia, Wendy Leisenring, David Hodgson, Lisa Diller, Lisa Kenney, Lindsay Morton, Amy Berrington de Gonzalez, Michael Arnold, Smita Bhatia, Rebecca M. Howell, Susan A. Smith, Leslie L. Robison, Gregory T. Armstrong, Kevin C. Oeffinger, Yutaka Yasui, Chaya S. Moskowitz
Summary: The study found that the risk of breast cancer in childhood cancer survivors has decreased over time, especially in those under 40 years old. This decline is mainly associated with the reduced use of chest radiation therapy, but is also influenced by other treatment modalities.
Article
Oncology
Yu-Chan Chang, Peter Mu-Hsin Chang, Chien-Hsiu Li, Ming-Hsien Chan, Yi-Jang Lee, Ming-Huang Chen, Michael Hsiao
Summary: Exposure to alkylating agents and radiation can cause damage and apoptosis in cancer cells, but also leads to resistance and metabolic reprogramming. This study reveals the dominant role of phospholipase D1 (PLD1) in these processes, affecting cancer cell proliferation, autophagy, and DNA repair capabilities by regulating specific metabolites lysophosphatidylethanolamine (LPE) and lysophosphatidylcholine (LPC). Additionally, aldolase A (ALDOA) inhibits PLD2 and enhances PLD1 and other carcinogenic features through protein-protein interaction (PPI). The combination of ALDOA and PLD1 serves as an independent prognostic factor in lung cancer and is correlated with clinical parameters.
FRONTIERS IN ONCOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Yuehan Wang, Cecile M. Ronckers, Flora E. van Leeuwen, Chaya S. Moskowitz, Wendy Leisenring, Gregory T. Armstrong, Florent de Vathaire, Melissa M. Hudson, Claudia E. Kuehni, Michael A. Arnold, Charlotte Demoor-Goldschmidt, Daniel M. Green, Tara O. Henderson, Rebecca M. Howell, Matthew J. Ehrhardt, Joseph P. Neglia, Kevin C. Oeffinger, Helena J. H. van der Pal, Leslie L. Robison, Michael Schaapveld, Lucie M. Turcotte, Nicolas Waespe, Nadia Haddy, Ibrahima Diallo, K. Scott Baker, Amy Berrington de Gonzalez, Miriam R. Conces, Louis S. Constine, Mike Hawkins, Jacqueline J. Loonen, Marloes Louwerens, Geert O. Janssens, Lene Mellemkjaer, Raoul Reulen, Jeanette F. Winther, Leontien C. M. Kremer, Jop C. Teepen
Summary: In this study, the association between anthracycline-based chemotherapy and subsequent breast cancer risk in female childhood cancer survivors was investigated. The findings suggest that there is a dose-dependent increased risk of subsequent breast cancer associated with doxorubicin, with a more than twofold increased risk for survivors treated with a cumulative doxorubicin dose of 200 mg/m² or higher. Early initiation of breast cancer surveillance may be reasonable for these survivors.
Article
Hematology
Simone de Vries, Inge M. Krul, Michael Schaapveld, Cecile P. M. Janus, Saskia E. Rademakers, Judith M. Roesink, Marten R. Nijziel, Berthe M. P. Aleman, Flora E. van Leeuwen
Summary: Male survivors of Hodgkin lymphoma who received chest radiotherapy have a significantly increased risk of breast cancer. The risk is higher for those who received chest radiotherapy and alkylating chemotherapy compared to those who only received chest radiotherapy.
Article
Oncology
Raoul C. Reulen, David L. Winter, Ibrahim Diallo, Cristina Veres, Damien Llanas, Rodrigue S. Allodji, Francesca Bagnasco, Edit Bardi, Elizabeth A. M. Feijen, Daniela Alessi, Miranda M. Fidler-Benaoudia, Stine Hogsholt, Jop C. Teepen, Helena Linge, Nadia Haddy, Julianne Byrne, Ghazi Debiche, Desiree Grabow, Thorgerdur Gudmundsdottir, Romain Fauchery, Wael Zrafi, Gisela Michel, Hilde ofstaas, Peter Kaatsch, Giao Vu-Bezin, Helen Jenkinson, Melanie Kaiser, Roderick Skinner, Trevor Cole, Nicolas Waespe, Grit Sommer, Susanne Nordenfelt, Momcilo Jankovic, Tuomas Lahteenmaki Taalas, Milena M. Maule, Helena J. H. van der Pal, Cecile M. Ronckers, Flora E. van Leeuwen, Judith L. Kok, Monica Terenziani, Maria Winther Gunnes, Thomas Wiebe, Carlotta Sacerdote, Zsuzsanna Jakab, Riccardo Haupt, Paivi M. Lahteenmaki, Lorna Zadravec Zaletel, Claudia E. Kuehni, Jeanette Falck Winther, Leontien C. M. Kremer, Lars Hjorth, Florent de Vathaire, Michael M. Hawkins
Summary: Radiation and exposure to alkylating agents increase the risk of bone cancer among survivors of childhood cancer. This study demonstrates, for the first time, that the risk of bone cancer is increased 5-10 fold after exposure of bone tissue to cumulative radiation doses of 1-9 Gy. Alkylating agents exceeding 10,000 mg/m(2), particularly procarbazine, ifosfamide, and cyclophosphamide, increase the risk 7-8 fold. These findings should be used to develop/update clinical follow-up guidelines and survivorship care plans.
JOURNAL OF CLINICAL ONCOLOGY
(2023)
Article
Oncology
Melvin J. Silverstein, Brian Kim, Kevin Lin, Shane Lloyd, Lincoln Snyder, Sadia Khan, Katherine Kramme, Peter Chen
Summary: Randomized trials have shown that risk-adapted intraoperative radiation therapy (IORT) is a safe alternative to whole-breast radiation therapy (WBRT) for low-risk breast cancer patients. Additional WBRT is given to patients with high-risk pathologic characteristics. However, the more WBRT is given, the less we understand the contribution of IORT as a stand-alone treatment.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Oncology
Daegan Sit, Nafisha Lalani, Elisa Chan, Eric Tran, Caroline Speers, Lovedeep Gondara, Stephen Chia, Karen Gelmon, Caroline Lohrisch, Alan Nichol
Summary: This study aimed to investigate whether regional nodal irradiation (RNI) improves breast cancer recurrence-free interval (BCRFI) in women with biologically low-risk N1 breast cancer. The population-based study found that RNI was not associated with improved BCRFI for this specific population.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
(2022)
Article
Multidisciplinary Sciences
Deepa Sharma, Christine M. Tarapacki, Harini Kandavel, Mailoan Panchalingam, Hyunjung Christina Kim, Holliday Cartar, Ahmed El Kaffas, Gregory J. Czarnota
Summary: Ultrasound-stimulated microbubbles (USMB) can enhance the effects of radiation therapy (XRT) on tumors by causing localized vascular effects. This study investigated the optimization of acoustic parameters for combining USMB and XRT in breast cancer xenograft tumors. The results showed that a pressure of 570 kPa, 1-minute exposure, and 1% (v/v) microbubble concentration resulted in significant cell death, while higher ultrasound pressure and exposure duration were required for significant microvascular disruption. Additionally, introducing a 6-hour delay between USMB and XRT did not further improve the tumor response compared to immediate XRT delivery.
Article
Oncology
Esmee C. de Baat, Elizabeth A. M. Feijen, Raoul C. Reulen, Rodrigue S. Allodji, Francesca Bagnasco, Edit Bardi, Fabien N. Belle, Julianne Byrne, Elvira C. van Dalen, Ghazi Debiche, Ibrahima Diallo, Desiree Grabow, Lars Hjorth, Momcilo Jankovic, Claudia E. Kuehni, Gill Levitt, Damien Llanas, Jacqueline Loonen, Lorna Z. Zaletel, Milena M. Maule, Lucia Miligi, Helena J. H. van der Pal, Cecile M. Ronckers, Carlotta Sacerdote, Roderick Skinner, Zsuzsanna Jakab, Cristina Veres, Nadia Haddy, David L. Winter, Florent de Vathaire, Michael M. Hawkins, Leontien C. M. Kremer
Summary: This study evaluated the risk and risk factors for heart failure in childhood cancer survivors and highlighted the impact of radiation therapy and anthracycline dose on the risk. These findings may have important implications for improving current treatment protocols and surveillance guidelines.
JOURNAL OF CLINICAL ONCOLOGY
(2023)
Article
Oncology
Isabelle M. Dudley, Ceren Sunguc, Emma J. Heymer, David L. Winter, Jop C. Teepen, Fabien N. Belle, Edit Bardi, Francesca Bagnasco, Thorgerdur Gudmundsdottir, Roderick Skinner, Gisela Michel, Julianne Byrne, Hilde Ofstaas, Momcilo Jankovic, Maja Cesen Mazic, Luzius Mader, Jaqueline Loonen, Stanislaw Garwicz, Thomas Wiebe, Daniela Alessi, Rodrigue S. Allodji, Nadia Haddy, Desiree Grabow, Peter Kaatsch, Melanie Kaiser, Milena M. Maule, Zsuzsanna Jakab, Maria Winther Gunnes, Monica Terenziani, Lorna Zadravec Zaletel, Claudia E. Kuehni, Riccardo Haupt, Florent de Vathaire, Leontien C. Kremer, Paivi M. Lahteenmaki, Jeanette F. Winther, Lars Hjorth, Michael M. Hawkins, Raoul C. Reulen
Summary: This study found that survivors of Hodgkin lymphoma (HL) are at an increased risk of developing non-Hodgkin lymphoma (NHL) after treatment. The researchers also identified other types of childhood cancer survivors who are at risk of developing NHL, including survivors of Wilms tumor, leukemia, and bone sarcoma. Treatment with chemotherapy increased the risk of NHL, while treatment with radiotherapy did not.
Article
Oncology
Imene Mansouri, Boris Schwartz, Giao Vu-Bezin, Daniel Bejarano-Quisoboni, Brice Fresneau, Chiraz El-Fayech, Christelle Dufour, Stephanie Bolle, Aurore Surun, Daniel Orbach, Rodrigue S. Allodji, Ibrahima Diallo, Charlotte Demoor-Goldschmidt, Florent de Vathaire, Nadia Haddy
Summary: This study aimed to determine the long-term risks of hospitalization related to renal and urinary diseases among 5-year childhood cancer survivors (CCS). The results showed that CCS had a higher risk of renal hospitalization compared to the general population, and radiation therapy with certain dose-volume indicators increased the risk. It also identified specific risk factors associated with hospitalization for renal causes among CCS.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2023)
Article
Oncology
Raoul C. Reulen, David L. Winter, Ibrahim Diallo, Cristina Veres, Damien Llanas, Rodrigue S. Allodji, Francesca Bagnasco, Edit Bardi, Elizabeth A. M. Feijen, Daniela Alessi, Miranda M. Fidler-Benaoudia, Stine Hogsholt, Jop C. Teepen, Helena Linge, Nadia Haddy, Julianne Byrne, Ghazi Debiche, Desiree Grabow, Thorgerdur Gudmundsdottir, Romain Fauchery, Wael Zrafi, Gisela Michel, Hilde ofstaas, Peter Kaatsch, Giao Vu-Bezin, Helen Jenkinson, Melanie Kaiser, Roderick Skinner, Trevor Cole, Nicolas Waespe, Grit Sommer, Susanne Nordenfelt, Momcilo Jankovic, Tuomas Lahteenmaki Taalas, Milena M. Maule, Helena J. H. van der Pal, Cecile M. Ronckers, Flora E. van Leeuwen, Judith L. Kok, Monica Terenziani, Maria Winther Gunnes, Thomas Wiebe, Carlotta Sacerdote, Zsuzsanna Jakab, Riccardo Haupt, Paivi M. Lahteenmaki, Lorna Zadravec Zaletel, Claudia E. Kuehni, Jeanette Falck Winther, Leontien C. M. Kremer, Lars Hjorth, Florent de Vathaire, Michael M. Hawkins
Summary: Radiation and exposure to alkylating agents increase the risk of bone cancer among survivors of childhood cancer. This study demonstrates, for the first time, that the risk of bone cancer is increased 5-10 fold after exposure of bone tissue to cumulative radiation doses of 1-9 Gy. Alkylating agents exceeding 10,000 mg/m(2), particularly procarbazine, ifosfamide, and cyclophosphamide, increase the risk 7-8 fold. These findings should be used to develop/update clinical follow-up guidelines and survivorship care plans.
JOURNAL OF CLINICAL ONCOLOGY
(2023)
Article
Clinical Neurology
Pierre-Emmanuel Sugier, Elise A. Lucotte, Cloe Domenighetti, Matthew H. Law, Mark M. Iles, Kevin Brown, Christopher Amos, James D. McKay, Rayjean J. Hung, Mojgan Karimi, Delphine Bacq-Daian, Anne Boland-Auge, Robert Olaso, Jean-francois Deleuze, Fabienne Lesueur, Evgenia Ostroumova, Ausrele Kesminiene, Florent de Vathaire, Pascal Guenel, Ashwin Ashok Kumar Sreelatha, Claudia Schulte, Sandeep Grover, Patrick May, Dheeraj R. Bobbili, Milena Radivojkov-Blagojevic, Peter Lichtner, Andrew B. Singleton, Dena G. Hernandez, Connor Edsall, George D. Mellick, Alexander Zimprich, Walter Pirker, Ekaterina Rogaeva, Anthony E. Lang, Sulev Koks, Pille Taba, Suzanne Lesage, Alexis Brice, Jean-Christophe Corvol, Marie-Christine Chartier-Harlin, Eugenie Mutez, Kathrin Brockmann, Angela B. Deutschlaender, Georges M. Hadjigeorgiou, Efthimios Dardiotis, Leonidas Stefanis, Athina Maria Simitsi, Enza Maria Valente, Simona Petrucci, Letizia Straniero, Anna Zecchinelli, Gianni Pezzoli, Laura Brighina, Carlo Ferrarese, Grazia Annesi, Andrea Quattrone, Monica Gagliardi, Hirotaka Matsuo, Akiyoshi Nakayama, Nobutaka Hattori, Kenya Nishioka, Sun Ju Chung, Yun Joong Kim, Pierre Kolber, Bart P. C. van de Warrenburg, Bastiaan R. Bloem, Jan Aasly, Mathias Toft, Lasse Pihlstrom, Leonor Correia Guedes, Joaquim J. Ferreira, Soraya Bardien, Jonathan Carr, Eduardo Tolosa, Mario Ezquerra, Pau Pastor, Monica Diez-Fairen, Karin Wirdefeldt, Nancy Pedersen, Caroline Ran, Andrea C. Belin, Andreas Puschmann, Emil Ygland Roedstroem, Carl E. Clarke, Karen E. Morrison, Manuela Tan, Dimitri Krainc, Lena F. Burbulla, Matt J. Farrer, Rejko Kruger, Thomas Gasser, Manu Sharma, Therese Truong, Alexis Elbaz
Summary: By using genome-wide association studies, this study found that Parkinson's disease (PD) is genetically correlated with melanoma and prostate cancer, while it is inversely correlated with ovarian cancer. These findings suggest that pleiotropic genes contribute to the association between PD and specific cancers.
MOVEMENT DISORDERS
(2023)
Article
Endocrinology & Metabolism
Laurene Delacourt, Rodrigue Allodji, Juliette Chappat, Nadia Haddy, Chiraz El-Fayech, Charlotte Demoor-Goldschmidt, Neige Journy, Stephanie Bolle, Cecile Thomas-Teinturier, Monia Zidane, Carole Rubino, Cristina Veres, Giao Vu-Bezin, Delphine Berchery, Claire Pluchart, Pierre-Yves Bondiau, Agnes Dumas, Nicolas Bougas, Jacques Grill, Christelle Dufour, Brice Fresneau, Helene Pacquement, Ibrahima Diallo, Francois Doz, Florent de Vathaire
Summary: This study aimed to identify risk factors for obesity in childhood cancer survivors (CCSs). The study found that CCSs had a lower risk of obesity compared to the general French population. However, brain tumor survivors had a significantly higher risk of developing obesity. Patients who received radiotherapy to the pituitary gland and those who received etoposide treatment also had an increased risk of obesity.
Article
Oncology
Stefania Chounta, Sarah Lemler, Nadia Haddy, Brice Fresneau, Imene Mansouri, Mahmoud Bentriou, Charlotte Demoor-Goldschmidt, Ibrahima Diallo, Vincent Souchard, Thi-Duyen Do, Cristina Veres, Aurore Surun, Francois Doz, Damien Llanas, Giao Vu-Bezin, Carole Rubino, Florent de Vathaire, Veronique Letort, Rodrigue Setcheou Allodji
Summary: This study investigates the dose-volume-effect relationships of valvular heart disease (VHD) in childhood cancer survivors after radiotherapy. The findings suggest that higher doses to the heart are associated with an increased risk of VHD. Age also plays a role in the risk.
RADIOTHERAPY AND ONCOLOGY
(2023)
Article
Medicine, General & Internal
Philip C. Haycock, Maria Carolina Borges, Kimberley Burrows, Rozenn N. Lemaitre, Stephen Burgess, Nikhil K. Khankari, Konstantinos K. Tsilidis, Tom R. Gaunt, Gibran Hemani, Jie Zheng, Therese Truong, Brenda M. Birmann, Tracy OMara, Amanda B. Spurdle, Mark M. Iles, Matthew H. Law, Susan L. Slager, Fatemeh Saberi Hosnijeh, Daniela Mariosa, Michelle Cotterchio, James R. Cerhan, Ulrike Peters, Stefan Enroth, Puya Gharahkhani, Loic Le Marchand, Ann C. Williams, Robert C. Block, Christopher I. Amos, Rayjean J. Hung, Wei Zheng, Marc J. Gunter, George Davey Smith, Caroline Relton, Richard M. Martin
Summary: Using Mendelian randomization, this study found that polyunsaturated fatty acids (PUFAs) may be causally related to colorectal cancer and esophageal squamous cell carcinoma, but they also increase the risk of inflammatory bowel disease.
Article
Oncology
Stefania Chounta, Rodrigue Allodji, Maria Vakalopoulou, Mahmoud Bentriou, Duyen Thi Do, Florent De Vathaire, Ibrahima Diallo, Brice Fresneau, Thibaud Charrier, Vincent Zossou, Stergios Christodoulidis, Sarah Lemler, Veronique Letort Le Chevalier
Summary: Childhood cancer survivors are at risk of experiencing late effects due to treatment complications, including Valvular Heart Disease (VHD) caused by radiation leakage during radiotherapy. This study explores the use of machine learning algorithms to accurately predict the risk of late VHD in survivors. The results show that the use of dosiomics features significantly improves the predictive capability of the models, especially in the sub-population with spatially heterogeneous dose distribution.
Article
Oncology
Afi Mawulawoe Sylvie Henyoh, Rodrigue S. S. Allodji, Florent de Vathaire, Marie-Christine Boutron-Ruault, Neige M. Y. Journy, Thi-Van-Trinh Tran
Review
Oncology
Nathan Benzazon, Julie Colnot, Francois de Kermenguy, Samir Achkar, Florent de Vathaire, Eric Deutsch, Charlotte Robert, Ibrahima Diallo
Summary: A growing body of scientific evidence suggests that low doses of ionizing radiation (< 2 Gy) can increase the risk of radiation-induced cancer and have significant impacts on immune responses. This has led to a renewed interest in evaluating the out-of-field dose in photon radiotherapy, with a focus on analytical models for calculation purposes. However, there is a lack of consensus and standardization in practices and metrics, making quantitative comparisons difficult. The use of neural networks shows promise in overcoming these limitations, but the lack of sufficient data sets is a major obstacle.
FRONTIERS IN ONCOLOGY
(2023)
Article
Medicine, General & Internal
Florent de Vathaire, Monia Zidane, Constance Xhaard, Vincent Souchard, Sylvie Chevillard, Catherine Ory, Frederique Rachedi, Sebastien Nunez, Axelle Leufroy, Laurent Noel, Thierry Guerin, Larys Shan, Frederique Bost-Bezeaud, Patrice Petitdier, Gilles Soubiran, Rodrigue Allodji, Yan Ren, Francoise Doyon, Marc Taquet, Jacques Gardon, Andre Bouville, Vladimir Drozdovitch
Summary: This study examines the association between radiation exposure from French nuclear tests and the risk of thyroid cancer. The results suggest that there is an increase in the risk of thyroid cancer, although the credibility of the findings is reduced due to inconsistencies with the initial study. The lifetime risk of thyroid cancer in the population of French Polynesia is estimated to be 2.3%.
Article
Oncology
Agnes Dumas, Karen Milcent, Nicolas Bougas, Daniel Bejarano-Quisoboni, Chiraz El Fayech, Helene Charreire, Odile Oberlin, Catherine Patte, Julie Allard, Eric Thebault, Amel Boumaraf, Amel Belhout, Vu-Bezin Giao, Vincent Souchard, Angela Jackson, Rodrigue Allodji, Dominique Valteau-Couanet, Christelle Dufour, Gilles Vassal, Nadia Haddy, Florent De Vathaire, Brice Fresneau
Summary: The study found that patients who received combined chemotherapy and radiotherapy, had bone sarcoma, central nervous system primitive tumor, or underwent autologous hematopoietic cell transplant were more likely to attend long-term follow-up visits. Additionally, factors such as health status, medical expenses, social status, and distance from the follow-up center also influenced attendance.