LRIG1 is a triple threat: ERBB negative regulator, intestinal stem cell marker and tumour suppressor

The Pan-ErbB Negative Regulator Lrig1 Is an Intestinal Stem Cell Marker that Functions as a Tumor Suppressor

(2012) Anne E. Powell et al.   CELL

Effects of RNAi-mediated gene silencing of LRIG1 on proliferation and invasion of glioma cells

(2012) Feng Mao et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Immunohistochemical analysis of LRIG proteins in meningiomas: correlation between estrogen receptor status and LRIG expression

(2012) Soma Ghasimi et al.   JOURNAL OF NEURO-ONCOLOGY

Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling

(2012) Vivian W. Y. Wong et al.   NATURE CELL BIOLOGY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Association of expression of Leucine-rich repeats and immunoglobulin-like domains 2 gene with invasiveness of pituitary adenoma

(2011) Huaqiu Zhang et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Lrig1 Is an Estrogen-Regulated Growth Suppressor and Correlates with Longer Relapse-Free Survival in ER -Positive Breast Cancer

(2011) S. R. Krig et al.   MOLECULAR CANCER RESEARCH

Unlocking Biomarker Discovery: Large Scale Application of Aptamer Proteomic Technology for Early Detection of Lung Cancer

(2011) Rachel M. Ostroff et al.   PLoS One

LRIG2 in contrast to LRIG1 predicts poor survival in early-stage squamous cell carcinoma of the uterine cervix

(2010) Håkan Hedman et al.   ACTA ONCOLOGICA

Identifying common prognostic factors in genomic cancer studies: A novel index for censored outcomes

(2010) Sigrid Rouam et al.   BMC BIOINFORMATICS

Paracrine regulation of growth factor signaling by shed leucine-rich repeats and immunoglobulin-like domains 1

(2010) Wei Yi et al.   EXPERIMENTAL CELL RESEARCH

LRIG1 and the liar paradox in prostate cancer: A study of the expression and clinical significance of LRIG1 in prostate cancer

(2010) Marcus Thomasson et al.   INTERNATIONAL JOURNAL OF CANCER

Vertebrate Lrig3-ErbB Interactions Occur In Vitro but Are Unlikely to Play a Role in Lrig3-Dependent Inner Ear Morphogenesis

(2010) Victoria E. Abraira et al.   PLoS One

Chromosome 3p12.3-p14.2 and 3q26.2-q26.32 Are Genomic Markers for Prognosis of Advanced Nasopharyngeal Carcinoma

(2009) J. J.-C. Sheu et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Inhibition of LRIG3 gene expression via RNA interference modulates the proliferation, cell cycle, cell apoptosis, adhesion and invasion of glioblastoma cell (GL15)

(2009) Mingjun Cai et al.   CANCER LETTERS

Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian Epidermis

(2009) Kim B. Jensen et al.   Cell Stem Cell

Cytoplasmic LRIG2 expression is associated with poor oligodendroglioma patient survival

(2009) Camilla Holmlund et al.   NEUROPATHOLOGY

Investigating the Targets of MIR-15a and MIR-16-1 in Patients with Chronic Lymphocytic Leukemia (CLL)

(2009) Katy Hanlon et al.   PLoS One

Suppression of the Negative Regulator LRIG1 Contributes to ErbB2 Overexpression in Breast Cancer

(2008) J. K. Miller et al.   CANCER RESEARCH

Lrig3 regulates neural crest formation in Xenopus by modulating Fgf and Wnt signaling pathways

(2008) H. Zhao et al.   DEVELOPMENT

Cross-repressive interactions between Lrig3 and netrin 1 shape the architecture of the inner ear

(2008) V. E. Abraira et al.   DEVELOPMENT

Pitfalls in immunohistochemical validation of tumor marker expression — Exemplified in invasive cancer of the uterine cervix

(2008) Dan Hellberg et al.   GYNECOLOGIC ONCOLOGY

Lrig1 Is an Endogenous Inhibitor of Ret Receptor Tyrosine Kinase Activation, Downstream Signaling, and Biological Responses to GDNF

(2008) F. Ledda et al.   JOURNAL OF NEUROSCIENCE

LRIG1 negatively regulates the oncogenic EGF receptor mutant EGFRvIII

(2008) M A Stutz et al.   ONCOGENE

LRIG1 and squamous epithelial uterine cervical cancer: correlation to prognosis, other tumor markers, sex steroid hormones, and smoking

(2007) A.K. LINDSTRÖM et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER