Development of a cyclin-dependent kinase inhibitor devoid of ABC transporter-dependent drug resistance

A novel small molecule hydroxamate preferentially inhibits HDAC6 activity and tumour growth

(2013) M Kaliszczak et al.   BRITISH JOURNAL OF CANCER

FLT-PET Is Superior to FDG-PET for Very Early Response Prediction in NPM-ALK-Positive Lymphoma Treated with Targeted Therapy

(2012) Z. Li et al.   CANCER RESEARCH

Optimization of the Antitumor Activity of Sequence-specific Pyrrolobenzodiazepine Derivatives Based on their Affinity for ABC Transporters

(2010) Maciej Kaliszczak et al.   AAPS Journal

Development of a new epidermal growth factor receptor positron emission tomography imaging agent based on the 3-cyanoquinoline core: Synthesis and biological evaluation

(2010) Federica Pisaneschi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Zosuquidar, a novel modulator of P-glycoprotein, does not improve the outcome of older patients with newly diagnosed acute myeloid leukemia: a randomized, placebo-controlled trial of the Eastern Cooperative Oncology Group 3999

(2010) L. D. Cripe et al.   BLOOD

Guidelines for the welfare and use of animals in cancer research

(2010) P Workman et al.   BRITISH JOURNAL OF CANCER

A Pharmacodynamic Study of Docetaxel in Combination with the P-glycoprotein Antagonist Tariquidar (XR9576) in Patients with Lung, Ovarian, and Cervical Cancer

(2010) R. J. Kelly et al.   CLINICAL CANCER RESEARCH

Phase I and Pharmacologic Study of SNS-032, a Potent and Selective Cdk2, 7, and 9 Inhibitor, in Patients With Advanced Chronic Lymphocytic Leukemia and Multiple Myeloma

(2010) Wei-Gang Tong et al.   JOURNAL OF CLINICAL ONCOLOGY

A Novel Pyrazolo[1,5-a]pyrimidine Is a Potent Inhibitor of Cyclin-Dependent Protein Kinases 1, 2, and 9, Which Demonstrates Antitumor Effects in Human Tumor Xenografts Following Oral Administration

(2010) Dean A. Heathcote et al.   JOURNAL OF MEDICINAL CHEMISTRY

Dinaciclib (SCH 727965), a Novel and Potent Cyclin-Dependent Kinase Inhibitor

(2010) David Parry et al.   MOLECULAR CANCER THERAPEUTICS

The Development of a Selective Cyclin-Dependent Kinase Inhibitor That Shows Antitumor Activity

(2009) S. Ali et al.   CANCER RESEARCH

Cell cycle kinases as therapeutic targets for cancer

(2009) Silvia Lapenna et al.   NATURE REVIEWS DRUG DISCOVERY

A diaminocyclohexyl analog of SNS-032 with improved permeability and bioavailability properties

(2008) Ingrid C. Choong et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Pharmacogenomics Approach Reveals MRP1 (ABCC1)-Mediated Resistance to Geldanamycins

(2008) Anh-Nhan Pham et al.   PHARMACEUTICAL RESEARCH