KRAS gene amplification and overexpression but not mutation associates with aggressive and metastatic endometrial cancer

Loss of GPER identifies new targets for therapy among a subgroup of ERα-positive endometrial cancer patients with poor outcome

(2012) C Krakstad et al.   BRITISH JOURNAL OF CANCER

KrasG12D-Induced IKK2/β/NF-κB Activation by IL-1α and p62 Feedforward Loops Is Required for Development of Pancreatic Ductal Adenocarcinoma

(2012) Jianhua Ling et al.   CANCER CELL

PI3K/AKT/mTOR Inhibitors in Patients With Breast and Gynecologic Malignancies HarboringPIK3CAMutations

(2012) Filip Janku et al.   JOURNAL OF CLINICAL ONCOLOGY

The tumour suppressor SOX11 is associated with improved survival among high grade epithelial ovarian cancers and is regulated by reversible promoter methylation

(2011) Sandra Sernbo et al.   BMC CANCER

Activated KrasG12D is associated with invasion and metastasis of pancreatic cancer cells through inhibition of E-cadherin

(2011) S Rachagani et al.   BRITISH JOURNAL OF CANCER

Metastatic Progression with Resistance to Aromatase Inhibitors Is Driven by the Steroid Receptor Coactivator SRC-1

(2011) J. McBryan et al.   CANCER RESEARCH

Stathmin Overexpression Identifies High-Risk Patients and Lymph Node Metastasis in Endometrial Cancer

(2011) J. Trovik et al.   CLINICAL CANCER RESEARCH

Frequency and clinicopathologic correlates of KRAS amplification in non-small cell lung carcinoma

(2011) Patrick L. Wagner et al.   LUNG CANCER

Emerging therapeutic targets in endometrial cancer

(2011) Konstantin J. Dedes et al.   Nature Reviews Clinical Oncology

Mutant K-Ras increases GSK-3β gene expression via an ETS-p300 transcriptional complex in pancreatic cancer

(2011) J-S Zhang et al.   ONCOGENE

MET and KRAS Gene Amplification Mediates Acquired Resistance to MET Tyrosine Kinase Inhibitors

(2010) V. Cepero et al.   CANCER RESEARCH

Evaluation of Kras Gene Mutation and Copy Number Gain in Non-small Cell Lung Cancer

(2010) Hidefumi Sasaki et al.   Journal of Thoracic Oncology

Hypoxia Activates the K-Ras Proto-Oncogene to Stimulate Angiogenesis and Inhibit Apoptosis in Colon Cancer Cells

(2010) Min Zeng et al.   PLoS One

In Situ Evidence of KRAS Amplification and Association With Increased p21 Levels in Non–Small Cell Lung Carcinoma

(2009) Patrick L. Wagner et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Mutations of the KRAS oncogene in endometrial hyperplasia and carcinoma.

(2009) Bozena Dobrzycka et al.   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation

(2009) H. B. Salvesen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GATA3 expression in estrogen receptor α-negative endometrial carcinomas identifies aggressive tumors with high proliferation and poor patient survival

(2008) Ingeborg B. Engelsen et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Endometrioid uterine cancer: Histopathological risk factors of local and distant recurrence

(2008) Toshio Fujimoto et al.   GYNECOLOGIC ONCOLOGY

Phase II Study of Erlotinib in Recurrent or Metastatic Endometrial Cancer: NCIC IND-148

(2008) Amit M. Oza et al.   JOURNAL OF CLINICAL ONCOLOGY