PBOX-15, a novel microtubule targeting agent, induces apoptosis, upregulates death receptors and potentiates TRAIL-mediated apoptosis in multiple myeloma cells

Exploiting the mevalonate pathway to distinguish statin-sensitive multiple myeloma

(2010) J. W. Clendening et al.   BLOOD

Novel pyrrolo-1,5-benzoxazepine compounds display significant activity against resistant chronic myeloid leukaemia cells in vitro, in ex vivo patient samples and in vivo

(2010) S A Bright et al.   BRITISH JOURNAL OF CANCER

Novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines, induce apoptosis in multi-drug-resistant cancer cells

(2009) Seema-Maria Nathwani et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

The Novel Tubulin-Targeting Agent Pyrrolo-1,5-Benzoxazepine-15 Induces Apoptosis in Poor Prognostic Subgroups of Chronic Lymphocytic Leukemia

(2009) A. M. McElligott et al.   CANCER RESEARCH

BH3-only proteins in apoptosis and beyond: an overview

(2009) E Lomonosova et al.   ONCOGENE

BH3-only proteins Noxa, Bmf, and Bim are necessary for arsenic trioxide-induced cell death in myeloma

(2008) A. A. Morales et al.   BLOOD

Multiple myeloma

(2008) R. A. Kyle et al.   BLOOD

Combined pegylated liposomal doxorubicin and bortezomib is highly effective in patients with recurrent or refractory multiple myeloma who received prior thalidomide/lenalidomide therapy

(2008) Pieter Sonneveld et al.   CANCER

Cancer Cells Display Profound Intra- and Interline Variation following Prolonged Exposure to Antimitotic Drugs

(2008) Karen E. Gascoigne et al.   CANCER CELL

Perifosine Synergistically Enhances TRAIL-Induced Myeloma Cell Apoptosis via Up-Regulation of Death Receptors

(2008) E. David et al.   CLINICAL CANCER RESEARCH

New Tubulin Polymerization Inhibitor Derived from Thalidomide: Implications for Anti-Myeloma Therapy

(2008) Masahiro Kizaki et al.   CURRENT MEDICINAL CHEMISTRY

A new microtubule-targeting compound PBOX-15 inhibits T-cell migration via post-translational modifications of tubulin

(2008) Navin K. Verma et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Genomic aberrations and immunohistochemical markers as prognostic indicators in multiple myeloma

(2007) J Yeung et al.   JOURNAL OF CLINICAL PATHOLOGY