Journal
BRITISH JOURNAL OF ANAESTHESIA
Volume 112, Issue 6, Pages 1105-1108Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bja/aeu048
Keywords
asthma; enoximone; intensive care; respiratory factors
Categories
Funding
- Carinopharm GmbH, Germany
- Carinopharm, UK
- Incapharm, Italy
- Devrimed
Ask authors/readers for more resources
This report describes the treatment of eight patients with status asthmaticus, six of whom were already maximally treated. They were consequently treated with enoximone, a selective phosphodiesterase III inhibitor, in their refractory phase. Bronchodilatation in these patients was immediate. No side-effects were observed. Enoximone appears to be a valuable addition to the treatment of status asthmaticus. I.V. administration bypasses inhalation incapability in severe asthma. It is likely to reduce or altogether prevent the need for resorting to secondary or tertiary high-tech therapy such as mechanical ventilation or anaesthetics, thus avoiding complications, as well as for transfers to specialized intensive care units. Not only do these aspects enable substantial cost savings, but they also may spare the patient a lot of anguish and a prolonged recovery.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available