The impact of post-transcriptional regulation in the p53 network

Multiple p53-independent gene silencing mechanisms define the cellular response to p53 activation

(2014) Ramiro París et al.   CELL CYCLE

Tumor Suppression in the Absence of p53-Mediated Cell-Cycle Arrest, Apoptosis, and Senescence

(2012) Tongyuan Li et al.   CELL

miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions

(2012) Helge Siemens et al.   CELL CYCLE

miR-205 regulates basement membrane deposition in human prostate: implications for cancer development

(2012) P Gandellini et al.   CELL DEATH AND DIFFERENTIATION

A DR4:tBID axis drives the p53 apoptotic response by promoting oligomerization of poised BAX

(2012) Ryan E Henry et al.   EMBO JOURNAL

STAR RNA-binding protein Quaking suppresses cancer via stabilization of specific miRNA

(2012) A.-J. Chen et al.   GENES & DEVELOPMENT

p73 Expression Is Regulated by RNPC1, a Target of the p53 Family, via mRNA Stability

(2012) W. Yan et al.   MOLECULAR AND CELLULAR BIOLOGY

Oncosuppressive role of p53-induced miR-205 in triple negative breast cancer

(2012) Claudia Piovan et al.   Molecular Oncology

The microcosmos of cancer

(2012) Amaia Lujambio et al.   NATURE

ATM and MET kinases are synthetic lethal with nongenotoxic activation of p53

(2012) Kelly D Sullivan et al.   Nature Chemical Biology

MiR-663, a microRNA targeting p21 WAF1/CIP1 , promotes the proliferation and tumorigenesis of nasopharyngeal carcinoma

(2012) C Yi et al.   ONCOGENE

MiR-200c Regulates Noxa Expression and Sensitivity to Proteasomal Inhibitors

(2012) Mikael Lerner et al.   PLoS One

Radiation Sensitivity of Esophageal Adenocarcinoma: The Contribution of the RNA-Binding Protein RNPC1 and p21-Mediated Cell Cycle Arrest to Radioresistance

(2012) Gijsbert J. Hötte et al.   RADIATION RESEARCH

miR-20a Encoded by the miR-17-92 Cluster Increases the Metastatic Potential of Osteosarcoma Cells by Regulating Fas Expression

(2011) G. Huang et al.   CANCER RESEARCH

Distinct p53 Transcriptional Programs Dictate Acute DNA-Damage Responses and Tumor Suppression

(2011) Colleen A. Brady et al.   CELL

BH3 activation blocks Hdmx suppression of apoptosis and cooperates with Nutlin to induce cell death

(2011) Mark Wade et al.   CELL CYCLE

The relative contribution of pro-apoptotic p53-target genes in the triggering of apoptosis following DNA damage in vitro and in vivo

(2011) Kageaki Kuribayashi et al.   CELL CYCLE

miR-605joins p53 network to form a p53:miR-605:Mdm2 positive feedback loop in response to stress

(2011) Jiening Xiao et al.   EMBO JOURNAL

Translational repression of p53 by RNPC1, a p53 target overexpressed in lymphomas

(2011) J. Zhang et al.   GENES & DEVELOPMENT

miR-17 92 cooperates with RB pathway mutations to promote retinoblastoma

(2011) K. Conkrite et al.   GENES & DEVELOPMENT

Let-7/miR-98 regulate Fas and Fas-mediated apoptosis

(2011) S Wang et al.   GENES AND IMMUNITY

p53 regulates epithelial–mesenchymal transition through microRNAs targeting ZEB1 and ZEB2

(2011) Taewan Kim et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Frequent methylation and oncogenic role of microRNA-34b/c in small-cell lung cancer

(2011) Norimitsu Tanaka et al.   LUNG CANCER

The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44

(2011) Can Liu et al.   NATURE MEDICINE

Capture of MicroRNA–Bound mRNAs Identifies the Tumor Suppressor miR-34a as a Regulator of Growth Factor Signaling

(2011) Ashish Lal et al.   PLoS Genetics

Downregulation of p53-inducible microRNAs 192, 194, and 215 Impairs the p53/MDM2 Autoregulatory Loop in Multiple Myeloma Development

(2010) Flavia Pichiorri et al.   CANCER CELL

Epigenetic inactivation of the miR-34a in hematological malignancies

(2010) C.S. Chim et al.   CARCINOGENESIS

RHAMM is differentially expressed in the cell cycle and downregulated by the tumor suppressor p53

(2010) Sindy Sohr et al.   CELL CYCLE

Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer

(2010) Dmitri Lodygin et al.   CELL CYCLE

The RNA binding protein Musashi1 regulates apoptosis, gene expression and stress granule formation in urothelial carcinoma cells

(2010) Parvaneh Nikpour et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

A Human Herpesvirus MicroRNA Inhibits p21 Expression and Attenuates p21-Mediated Cell Cycle Arrest

(2010) E. Gottwein et al.   JOURNAL OF VIROLOGY

MiR-221 and miR-222 target PUMA to induce cell survival in glioblastoma

(2010) Chun-Zhi Zhang et al.   Molecular Cancer

RNPC1 modulates the RNA-binding activity of, and cooperates with, HuR to regulate p21 mRNA stability

(2010) S. J. Cho et al.   NUCLEIC ACIDS RESEARCH

The cyclin-dependent kinase inhibitor p21 is regulated by RNA-binding protein PCBP4 via mRNA stability

(2010) Ariane Scoumanne et al.   NUCLEIC ACIDS RESEARCH

RNPC1, an RNA-binding protein and a target of the p53 family, regulates p63 expression through mRNA stability

(2010) J. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation

(2009) Michela Garofalo et al.   CANCER CELL

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Protein phosphatases take the mitotic stage

(2009) Peter De Wulf et al.   CURRENT OPINION IN CELL BIOLOGY

MicroRNAs Impair MET-Mediated Invasive Growth

(2008) C. Migliore et al.   CANCER RESEARCH

Epigenetic Silencing of MicroRNA-34b/c and B-Cell Translocation Gene 4 Is Associated with CpG Island Methylation in Colorectal Cancer

(2008) M. Toyota et al.   CANCER RESEARCH

Growth-Inhibitory and Tumor- Suppressive Functions of p53 Depend on Its Repression of CD44 Expression

(2008) Samuel Godar et al.   CELL

Downregulation of CCND1 and CDK6 by miR-34a induces cell cycle arrest

(2008) Fang Sun et al.   FEBS LETTERS

Cell-surface and mitotic-spindle RHAMM: moonlighting or dual oncogenic functions?

(2008) C. A. Maxwell et al.   JOURNAL OF CELL SCIENCE

MicroRNAs in the miR-106b Family Regulate p21/CDKN1A and Promote Cell Cycle Progression

(2008) I. Ivanovska et al.   MOLECULAR AND CELLULAR BIOLOGY

Transcriptional control of human p53-regulated genes

(2008) Todd Riley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Antagomir-17-5p Abolishes the Growth of Therapy-Resistant Neuroblastoma through p21 and BIM

(2008) Laura Fontana et al.   PLoS One