4.5 Article

Genome-wide approaches to understanding behaviour in Drosophila melanogaster

Journal

BRIEFINGS IN FUNCTIONAL GENOMICS
Volume 11, Issue 5, Pages 395-404

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/bfgp/els031

Keywords

Drosophila; transcriptomics; behaviour; circadian rhythms; courtship; learning; memory

Funding

  1. Wellcome Trust [WT085521]
  2. Biotechnology and Biological Sciences Research Council [BBS/B/0837X] Funding Source: researchfish

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Understanding how an organism exhibits specific behaviours remains a major and important biological question. Studying behaviour in a simple model organism like the fruit fly Drosophila melanogaster has the advantages of advanced molecular genetics approaches along with well-defined anatomy and physiology. With advancements in functional genomic technologies, researchers are now attempting to uncover genes and pathways involved in complex behaviours on a genome-wide scale. A systems-level network approach, which will include genomic approaches, to study behaviour will be key to understanding the regulation and modulation of behaviours and the importance of context in regulating them.

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