Genomic approaches to the initiation of DNA replication and chromatin structure reveal a complex relationship

Regulation of the initiation step of DNA replication by cyclin-dependent kinases

(2010) Seiji Tanaka et al.   CHROMOSOMA

Nucleotide supply, not local histone acetylation, sets replication origin usage in transcribed regions

(2010) Sophie Gay et al.   EMBO REPORTS

The conserved bromo-adjacent homology domain of yeast Orc1 functions in the selection of DNA replication origins within chromatin

(2010) P. Muller et al.   GENES & DEVELOPMENT

Conserved nucleosome positioning defines replication origins

(2010) M. L. Eaton et al.   GENES & DEVELOPMENT

Relicensing of Transcriptionally Inactivated Replication Origins in Budding Yeast

(2010) Marko Lõoke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Single-Molecule Analysis Reveals Changes in the DNA Replication Program for the POU5F1 Locus upon Human Embryonic Stem Cell Differentiation

(2010) S. S. Schultz et al.   MOLECULAR AND CELLULAR BIOLOGY

The Dbf4–Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4

(2010) Yi-Jun Sheu et al.   NATURE

Evaluating genome-scale approaches to eukaryotic DNA replication

(2010) David M. Gilbert   NATURE REVIEWS GENETICS

High Nucleosome Occupancy Is Encoded at Human Regulatory Sequences

(2010) Desiree Tillo et al.   PLoS One

Genome-Wide Kinetics of Nucleosome Turnover Determined by Metabolic Labeling of Histones

(2010) R. B. Deal et al.   SCIENCE

Genome-wide analysis of the replication program in mammals

(2009) Shlomit Farkash-Amar et al.   CHROMOSOME RESEARCH

Why are we where we are? Understanding replication origins and initiation sites in eukaryotes using ChIP-approaches

(2009) Aloys Schepers et al.   CHROMOSOME RESEARCH

Genome-wide approaches to determining origin distribution

(2009) Jean-Charles Cadoret et al.   CHROMOSOME RESEARCH

Domain-wide regulation of DNA replication timing during mammalian development

(2009) Benjamin D. Pope et al.   CHROMOSOME RESEARCH

Drosophila ORC localizes to open chromatin and marks sites of cohesin complex loading

(2009) H. K. MacAlpine et al.   GENOME RESEARCH

Decreased replication origin activity in temporal transition regions

(2009) Zeqiang Guan et al.   JOURNAL OF CELL BIOLOGY

Sequencing newly replicated DNA reveals widespread plasticity in human replication timing

(2009) R. S. Hansen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcription Initiation Activity Sets Replication Origin Efficiency in Mammalian Cells

(2009) Joana Sequeira-Mendes et al.   PLoS Genetics

Dynamic Regulation of Nucleosome Positioning in the Human Genome

(2008) Dustin E. Schones et al.   CELL

Global organization of replication time zones of the mouse genome

(2008) S. Farkash-Amar et al.   GENOME RESEARCH

Replication fork movement sets chromatin loop size and origin choice in mammalian cells

(2008) Sylvain Courbet et al.   NATURE

The DNA-encoded nucleosome organization of a eukaryotic genome

(2008) Noam Kaplan et al.   NATURE

DNA physical properties determine nucleosome occupancy from yeast to fly

(2008) Vincent Miele et al.   NUCLEIC ACIDS RESEARCH

Genome-wide studies highlight indirect links between human replication origins and gene regulation

(2008) J.-C. Cadoret et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication

(2008) Arkaitz Ibarra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global Reorganization of Replication Domains During Embryonic Stem Cell Differentiation

(2008) Ichiro Hiratani et al.   PLOS BIOLOGY