Reconsideration of in silico siRNA design from a perspective of heterogeneous data integration: problems and solutions
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Reconsideration of in silico siRNA design from a perspective of heterogeneous data integration: problems and solutions
Authors
Keywords
-
Journal
BRIEFINGS IN BIOINFORMATICS
Volume 15, Issue 2, Pages 292-305
Publisher
Oxford University Press (OUP)
Online
2012-12-30
DOI
10.1093/bib/bbs073
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Modifications in Small Interfering RNA That Separate Immunostimulation from RNA Interference
- (2014) F. Eberle et al. JOURNAL OF IMMUNOLOGY
- Asymmetric siRNA: New Strategy to Improve Specificity and Reduce Off-Target Gene Expression
- (2012) Zhongping Yuan et al. HUMAN GENE THERAPY
- Enhanced intracellular delivery and multi-target gene silencing triggered by tripodal RNA structures
- (2012) Chan Il Chang et al. JOURNAL OF GENE MEDICINE
- Self-assembled RNA interference microsponges for efficient siRNA delivery
- (2012) Jong Bum Lee et al. NATURE MATERIALS
- Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery
- (2012) Hyukjin Lee et al. Nature Nanotechnology
- Reconsideration of In-Silico siRNA Design Based on Feature Selection: A Cross-Platform Data Integration Perspective
- (2012) Qi Liu et al. PLoS One
- MysiRNA-Designer: A Workflow for Efficient siRNA Design
- (2011) Mohamed Mysara et al. PLoS One
- Rapid match-searching for gene silencing assessment
- (2010) M. E. T. Horn et al. BIOINFORMATICS
- Multi-task learning for cross-platform siRNA efficacy prediction: an in-silico study
- (2010) Qi Liu et al. BMC BIOINFORMATICS
- Recent Progress in Chemically Modified siRNAs
- (2010) M. Gaglione et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Cheminformatics Approach to Gene Silencing: Z Descriptors of Nucleotides and SVM Regression Afford Predictive Models for siRNA Potency
- (2010) Jerry O. Ebalunode et al. Molecular Informatics
- mRNA turnover rate limits siRNA and microRNA efficacy
- (2010) Erik Larsson et al. Molecular Systems Biology
- Target mRNA abundance dilutes microRNA and siRNA activity
- (2010) Aaron Arvey et al. Molecular Systems Biology
- Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication
- (2010) Alexander Karlas et al. NATURE
- Small RNA sorting: matchmaking for Argonautes
- (2010) Benjamin Czech et al. NATURE REVIEWS GENETICS
- Thermodynamic contributions of single internal rA·dA, rC·dC, rG·dG and rU·dT mismatches in RNA/DNA duplexes
- (2010) Norman E. Watkins et al. NUCLEIC ACIDS RESEARCH
- Small RNA class transition from siRNA/piRNA to miRNA during pre-implantation mouse development
- (2010) Yusuke Ohnishi et al. NUCLEIC ACIDS RESEARCH
- Approximate Bayesian feature selection on a large meta-dataset offers novel insights on factors that effect siRNA potency
- (2009) Jochen W. Klingelhoefer et al. BIOINFORMATICS
- siDirect 2.0: updated software for designing functional siRNA with reduced seed-dependent off-target effect
- (2009) Yuki Naito et al. BMC BIOINFORMATICS
- A Genome-wide RNAi Screen Identifies Multiple Synthetic Lethal Interactions with the Ras Oncogene
- (2009) Ji Luo et al. CELL
- Origins and Mechanisms of miRNAs and siRNAs
- (2009) Richard W. Carthew et al. CELL
- Knocking down barriers: advances in siRNA delivery
- (2009) Kathryn A. Whitehead et al. NATURE REVIEWS DRUG DISCOVERY
- Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application
- (2009) Aimee L. Jackson et al. NATURE REVIEWS DRUG DISCOVERY
- Small silencing RNAs: an expanding universe
- (2009) Megha Ghildiyal et al. NATURE REVIEWS GENETICS
- A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity
- (2009) Jesper B. Bramsen et al. NUCLEIC ACIDS RESEARCH
- siRNA and Innate Immunity
- (2009) Marjorie Robbins et al. OLIGONUCLEOTIDES
- Sorting of Drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway
- (2009) M. Ghildiyal et al. RNA
- siDRM: an effective and generally applicable online siRNA design tool
- (2008) Wuming Gong et al. BIOINFORMATICS
- Sorting of Small RNAs into Arabidopsis Argonaute Complexes Is Directed by the 5′ Terminal Nucleotide
- (2008) Shijun Mi et al. CELL
- Misinterpreting the Therapeutic Effects of Small Interfering RNA Caused by Immune Stimulation
- (2008) Marjorie Robbins et al. HUMAN GENE THERAPY
- Nonviral Methods for siRNA Delivery
- (2008) Kun Gao et al. MOLECULAR PHARMACEUTICS
- Early origins and evolution of microRNAs and Piwi-interacting RNAs in animals
- (2008) Andrew Grimson et al. NATURE
- The impact of target site accessibility on the design of effective siRNAs
- (2008) Hakim Tafer et al. NATURE BIOTECHNOLOGY
- RNA major groove modifications improve siRNA stability and biological activity
- (2008) Montserrat Terrazas et al. NUCLEIC ACIDS RESEARCH
- AsiDesigner: exon-based siRNA design server considering alternative splicing
- (2008) Young-Kyu Park et al. NUCLEIC ACIDS RESEARCH
- OligoWalk: an online siRNA design tool utilizing hybridization thermodynamics
- (2008) Z. J. Lu et al. NUCLEIC ACIDS RESEARCH
- IDT SciTools: a suite for analysis and design of nucleic acid oligomers
- (2008) R. Owczarzy et al. NUCLEIC ACIDS RESEARCH
- Experimental validation of the importance of seed complement frequency to siRNA specificity
- (2008) E. M. Anderson et al. RNA
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now