When orthologs diverge between human and mouse

Functional Redundancy between HumanSHOXand MouseShox2Genes in the Regulation of Sinoatrial Node Formation and Pacemaking Function

(2011) Hongbing Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice

(2011) A. T. Franco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assessment of orthologous splicing isoforms in human and mouse orthologous genes

(2010) Federico Zambelli et al.   BMC GENOMICS

Age-dependent gain of alternative splice forms and biased duplication explain the relation between splicing and duplication

(2010) J. Roux et al.   GENOME RESEARCH

Differential regulation of human and murine P-selectin expression and function in vivo

(2010) Zhenghui Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The role of mutant p53 in human cancer

(2010) Amanda M Goh et al.   JOURNAL OF PATHOLOGY

The Gene Expression Barcode: leveraging public data repositories to begin cataloging the human and murine transcriptomes

(2010) Matthew N. McCall et al.   NUCLEIC ACIDS RESEARCH

Systematic discovery of nonobvious human disease models through orthologous phenotypes

(2010) K. L. McGary et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recent de novo origin of human protein-coding genes

(2009) D. G. Knowles et al.   GENOME RESEARCH

Adaptive evolution of young gene duplicates in mammals

(2009) M. V. Han et al.   GENOME RESEARCH

Thymic progenitor homing and lymphocyte homeostasis are linked via S1P-controlled expression of thymic P-selectin/CCL25

(2009) Klaus Gossens et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Segmental copy number variation shapes tissue transcriptomes

(2009) Charlotte N Henrichsen et al.   NATURE GENETICS

How confident can we be that orthologs are similar, but paralogs differ?

(2009) Romain A. Studer et al.   TRENDS IN GENETICS

The “street light syndrome”, or how protein taxonomy can bias experimental manipulations

(2008) Gabriel Markov et al.   BIOESSAYS

Low conservation and species-specific evolution of alternative splicing in humans and mice: comparative genomics analysis using well-annotated full-length cDNAs

(2008) Jun-ichi Takeda et al.   NUCLEIC ACIDS RESEARCH

Selectome: a database of positive selection

(2008) E. Proux et al.   NUCLEIC ACIDS RESEARCH

McKusick's Online Mendelian Inheritance in Man (OMIM(R))

(2008) J. Amberger et al.   NUCLEIC ACIDS RESEARCH

Null mutations in human and mouse orthologs frequently result in different phenotypes

(2008) B.-Y. Liao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Large-scale assignment of orthology: back to phylogenetics?

(2008) Toni Gabaldón   GENOME BIOLOGY