Sphingosine kinase 1 contributes to leptin-induced STAT3 phosphorylation through IL-6/gp130 transactivation in oestrogen receptor-negative breast cancer

Adipocyte Lipolysis-stimulated Interleukin-6 Production Requires Sphingosine Kinase 1 Activity

(2014) Wenliang Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

STAT3 Signaling Is Activated Preferentially in Tumor-Initiating Cells in Claudin-Low Models of Human Breast Cancer

(2014) Wei Wei et al.   STEM CELLS

A mechanism for epithelial–mesenchymal transition and anoikis resistance in breast cancer triggered by zinc channel ZIP6 and STAT3 (signal transducer and activator of transcription 3)

(2013) Christer Hogstrand et al.   BIOCHEMICAL JOURNAL

Activation of the FGFR-STAT3 Pathway in Breast Cancer Cells Induces a Hyaluronan-Rich Microenvironment That Licenses Tumor Formation

(2013) L. R. Bohrer et al.   CANCER RESEARCH

Obesity and the Risk for Premenopausal and Postmenopausal Breast Cancer

(2012) G. L. Anderson et al.   Cancer Prevention Research

Cancer-Associated Adipocytes Exhibit an Activated Phenotype and Contribute to Breast Cancer Invasion

(2011) B. Dirat et al.   CANCER RESEARCH

The multifactorial role of leptin in driving the breast cancer microenvironment

(2011) Sebastiano Andò et al.   Nature Reviews Endocrinology

Therapeutic potential of targeting sphingosine kinase 1 in prostate cancer

(2011) Dmitri Pchejetski et al.   Nature Reviews Urology

High Expression of Sphingosine 1-Phosphate Receptors, S1P1 and S1P3, Sphingosine Kinase 1, and Extracellular Signal-Regulated Kinase-1/2 Is Associated with Development of Tamoxifen Resistance in Estrogen Receptor-Positive Breast Cancer Patients

(2010) Carol Watson et al.   AMERICAN JOURNAL OF PATHOLOGY

Leptin enhances growth inhibition by cAMP elevating agents through apoptosis of MDA-MB-231 breast cancer cells

(2010) Silvio Naviglio et al.   CANCER BIOLOGY & THERAPY

Benzyl isothiocyanate inhibits oncogenic actions of leptin in human breast cancer cells by suppressing activation of signal transducer and activator of transcription 3

(2010) Su-Hyeong Kim et al.   CARCINOGENESIS

The involvement of sphingosine kinase 1 in LPS-induced Toll-like receptor 4-mediated accumulation of HIF-1α protein, activation of ASK1 and production of the pro-inflammatory cytokine IL-6

(2010) Dmitri Pchejetski et al.   IMMUNOLOGY AND CELL BIOLOGY

Correlation of body mass index and leptin with tumor size and stage of disease in hormone-dependent postmenopausal breast cancer: preliminary results and therapeutic implications

(2010) Antonio Macciò et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Obesity and Breast Cancer: The Estrogen Connection

(2009) Margot P. Cleary et al.   ENDOCRINOLOGY

Sphingosine kinase 1 inhibition sensitizes hormone-resistant prostate cancer to docetaxel

(2009) Lysann Sauer et al.   INTERNATIONAL JOURNAL OF CANCER

STAT3 can be activated through paracrine signaling in breast epithelial cells

(2008) Jacqueline C Lieblein et al.   BMC CANCER

Global burden of obesity in 2005 and projections to 2030

(2008) T Kelly et al.   INTERNATIONAL JOURNAL OF OBESITY

Leptin Stimulates Both JAK2-dependent and JAK2-independent Signaling Pathways

(2008) Lin Jiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY