Dichloroacetate enhances apoptotic cell death via oxidative damage and attenuates lactate production in metformin-treated breast cancer cells

Sensitization of metformin-cytotoxicity by dichloroacetate via reprogramming glucose metabolism in cancer cells

(2014) Yong Won Choi et al.   CANCER LETTERS

Metformin Induces Both Caspase-Dependent and Poly(ADP-ribose) Polymerase-Dependent Cell Death in Breast Cancer Cells

(2011) Y. Zhuang et al.   MOLECULAR CANCER RESEARCH

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

(2010) T.-C. Chou   CANCER RESEARCH

γH2AX: a sensitive molecular marker of DNA damage and repair

(2010) L-J Mah et al.   LEUKEMIA

Mitochondrial and plasma membrane lactate transporter and lactate dehydrogenase isoform expression in breast cancer cell lines

(2010) Rajaa Hussien et al.   PHYSIOLOGICAL GENOMICS

Metabolic Modulation of Glioblastoma with Dichloroacetate

(2010) E. D. Michelakis et al.   Science Translational Medicine

New Users of Metformin Are at Low Risk of Incident Cancer: A cohort study among people with type 2 diabetes

(2009) G. Libby et al.   DIABETES CARE

Metformin and Pathologic Complete Responses to Neoadjuvant Chemotherapy in Diabetic Patients With Breast Cancer

(2009) Sao Jiralerspong et al.   JOURNAL OF CLINICAL ONCOLOGY

Lactate Dehydrogenase 5 Expression in Squamous Cell Head and Neck Cancer Relates to Prognosis following Radical or Postoperative Radiotherapy

(2009) Michael I. Koukourakis et al.   ONCOLOGY

Role of dichloroacetate in the treatment of genetic mitochondrial diseases☆

(2008) Peter W. Stacpoole et al.   ADVANCED DRUG DELIVERY REVIEWS

Therapeutic metformin/AMPK activation promotes the angiogenic phenotype in the ERα negative MDA-MB-435 breast cancer model

(2008) Sirwan M. Hadad et al.   BREAST CANCER RESEARCH AND TREATMENT

PDK-1 regulates lactate production in hypoxia and is associated with poor prognosis in head and neck squamous cancer

(2008) S M Wigfield et al.   BRITISH JOURNAL OF CANCER

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

(2008) Ralph J. DeBerardinis et al.   Cell Metabolism

Methyl succinate antagonises biguanide-induced AMPK-activation and death of pancreatic β-cells through restoration of mitochondrial electron transfer

(2007) S A Hinke et al.   BRITISH JOURNAL OF PHARMACOLOGY