Pigment epithelium-derived factor (PEDF) inhibits breast cancer metastasis by down-regulating fibronectin

Targeting the PI3K/AKT/mTOR and Raf/MEK/ERK pathways in the treatment of breast cancer

(2013) Kamal S. Saini et al.   CANCER TREATMENT REVIEWS

Host pigment epithelium-derived factor (PEDF) prevents progression of liver metastasis in a mouse model of uveal melanoma

(2013) John M. Lattier et al.   CLINICAL & EXPERIMENTAL METASTASIS

Expression and prognostic significance of fibronectin and matrix metalloproteases in breast cancer metastasis

(2013) Belen Fernandez-Garcia et al.   HISTOPATHOLOGY

Fibronectin expression in carcinoma cells correlates with tumor aggressiveness and poor clinical outcome in patients with invasive breast cancer

(2013) Young Kyung Bae et al.   HUMAN PATHOLOGY

Dual Inhibition of Plasminogen Kringle 5 on Angiogenesis and Chemotaxis Suppresses Tumor Metastasis by Targeting HIF-1α Pathway

(2013) Wei-Bin Cai et al.   PLoS One

Cross-talk between mitogenic Ras/MAPK and survival PI3K/Akt pathways: a fine balance

(2012) Edita Aksamitiene et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Opposing Effects of Pigment Epithelium-Derived Factor on Breast Cancer Cell versus Neuronal Survival: Implication for Brain Metastasis and Metastasis-Induced Brain Damage

(2012) D. P. Fitzgerald et al.   CANCER RESEARCH

Epigallocatechin-3-gallate potentiates curcumin’s ability to suppress uterine leiomyosarcoma cell growth and induce apoptosis

(2012) Akiko Kondo et al.   International Journal of Clinical Oncology

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Strategies to target molecules that control the acquisition of a mesenchymal-like phenotype by carcinoma cells

(2011) Claudia Palena et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Identification of a Novel Inhibitor of the Canonical Wnt Pathway

(2011) K. Park et al.   MOLECULAR AND CELLULAR BIOLOGY

PI3K inhibition results in enhanced HER signaling and acquired ERK dependency in HER2-overexpressing breast cancer

(2011) V Serra et al.   ONCOGENE

Plasma Fibronectin Promotes Lung Metastasis by Contributions to Fibrin Clots and Tumor Cell Invasion

(2010) Gunjan Malik et al.   CANCER RESEARCH

The Role of PEDF in Tumor Growth and Metastasis

(2010) D. Hoshina et al.   CURRENT MOLECULAR MEDICINE

The Role of MAPK-ERK Pathway in 67-kDa Laminin Receptor-Induced FasL Expression in Human Cholangiocarcinoma Cells

(2010) Shi-Gang Duan et al.   DIGESTIVE DISEASES AND SCIENCES

Evaluation of protein pigment epithelium-derived factor (PEDF) and microvessel density (MVD) as prognostic indicators in breast cancer

(2010) Dan Zhou et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Ligand-independent activation of c-Met by fibronectin and α5β1-integrin regulates ovarian cancer invasion and metastasis

(2010) A K Mitra et al.   ONCOGENE

Culture of human breast cancer cell line (MDA-MB-231) on fibronectin-coated surface induces pro-matrix metalloproteinase-9 expression and activity

(2010) Gargi Maity et al.   TUMOR BIOLOGY

The Fibrotic Phenotype Induced by IGFBP-5 Is Regulated by MAPK Activation and Egr-1-Dependent and -Independent Mechanisms

(2009) Hidekata Yasuoka et al.   AMERICAN JOURNAL OF PATHOLOGY

In vitroandin vivobiological activity of PEDF against a range of tumors

(2009) Matthew L Broadhead et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Laminin Receptor Involvement in the Anti-angiogenic Activity of Pigment Epithelium-derived Factor

(2009) Adrien Bernard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of PEDF: A multi-functional serpin family protein

(2009) S. Filleur et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

‘Loss of pigment epithelium-derived factor enables migration, invasion and metastatic spread of human melanoma’

(2009) J L Orgaz et al.   ONCOGENE

Rapid expression and activation of MMP-2 and MMP-9 upon exposure of human breast cancer cells (MCF-7) to fibronectin in serum free medium

(2007) Shamik Das et al.   LIFE SCIENCES