Article
Chemistry, Multidisciplinary
Hyo-Seol Lee, Hee Jin Kim, Koeun Lee, Mi Sun Kim, Ok Hyung Nam, Sung-Chul Choi
Summary: A study reported the clinical process of a patient with MIM and investigated the pathogenesis through microbiome analysis. The results indicated that MIM teeth caused localized tooth-related periodontitis with pulp necrosis rather than juvenile periodontitis.
APPLIED SCIENCES-BASEL
(2021)
Article
Dentistry, Oral Surgery & Medicine
A. Rainer Jordan, H. Stark, I Nitschke, W. Micheelis, F. Schwendicke
Summary: Based on the data from the German Oral Health Studies, it is predicted that by 2030, the average number of missing teeth in adults will decrease by two-thirds to 1.3, while the average number of missing teeth in seniors aged 65-74 will decline to 5.6, also a two-thirds reduction. The prevalence of tooth loss is expected to decrease by 72% by 2030, with half of the adult population and about one-third of seniors not exhibiting any tooth loss by that time.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Dentistry, Oral Surgery & Medicine
Anna Trullenque-Eriksson, Cristiano Tomasi, Max Petzold, Tord Berglundh, Jan Derks
Summary: This registry-based retrospective cohort study found that furcation status has a significant impact on the risk for molar loss. Molars with furcation involvement of degree 2 and 3 have higher risk compared to those without furcation involvement. Additionally, endodontic status and probing depth are also relevant risk factors for molar loss.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2023)
Article
Multidisciplinary Sciences
Katsuaki Kuremoto, Rena Okawa, Saaya Matayoshi, Kazuma Kokomoto, Kazuhiko Nakano
Summary: Assessment of children's growth and development based on dental age and general and oral developmental status is important in pediatric dentistry. This study examined the correlation between chronological and dental age of permanent teeth in Japanese children and adolescents. The findings indicate that gender and developmental stage play a role in the rate of tooth formation.
SCIENTIFIC REPORTS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Bhawna Koli, Amrita Chawla, Ajay Logani, Vijay Kumar, Sidhartha Sharma
Summary: This prospective study evaluated the outcome of a combination of NSET and VPT in the management of mature permanent mandibular molar teeth with symptomatic irreversible pulpitis (SIP) and apical periodontitis (AP). The success rates of the NSET and NSET-VPT groups were 90% and 93.3% respectively, with no significant difference between the two groups, indicating that the combination of NSET and VPT is an effective treatment option.
JOURNAL OF ENDODONTICS
(2021)
Article
Endocrinology & Metabolism
Doaa Taqi, Hanan Moussa, Timothy Schwinghamer, Alexandre Rezende Vieira, Didem Dagdeviren, Jean-Marc Retrouvey, Frank Rauch, Faleh Tamimi
Summary: This study investigated the prevalence of missing and unerupted teeth in OI patients, finding that these abnormalities are related to clinical phenotype, genetic variant type, and treatment methods. The findings suggest that the occurrence of missing and unerupted teeth is associated with the nature of collagen variants and the type of OI.
Article
Nanoscience & Nanotechnology
Yi Tao, Hui Dong, Ying Ma, Long Han
Summary: The study utilized AZM-PLGA microspheres of different specifications as implant materials for the treatment of periodontitis, achieving favorable results in both animal models and clinical trials. The microspheres demonstrated good biocompatibility and mechanical properties, showing potential for application in periodontal treatment.
SCIENCE OF ADVANCED MATERIALS
(2021)
Article
Medicine, General & Internal
Julie A. Stephens, James L. Fisher, Robert Wesolowski, Electra D. Paskett
Summary: This cross-sectional study suggests that there needs to be greater focus on hormone receptor and ERBB2 testing in all women with invasive breast cancer, despite the standard of care recommended by all expert guidelines. The results of this study may help clinicians, public health practitioners, and policymakers target affected populations to minimize or eliminate this critical health disparity and help save more lives.
Article
Dentistry, Oral Surgery & Medicine
Fernando Oliveira Costa, Jose Roberto Cortelli, Sheila Cavalca Cortelli, Amanda Almeida Costa, Rafael Paschoal Esteves Lima, Adriana Moreira Costa, Gustavo Henrique Mattos Pereira, Luis Otavio Miranda Cota
Summary: The aim of this study was to assess the impact of furcation involvement on the longevity of molars and identify the risk variables associated with molar loss in individuals receiving supportive periodontal care. The study found that patient-related factors such as age, gender, diabetes, and smoking, as well as tooth-related factors like tooth vitality and periodontal parameters, significantly influenced the prognosis of molars.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2022)
Article
Biology
Peter Yanni, Donald A. Curtis, Richard T. Kao, Guo-Hao Lin
Summary: This study investigated the reasons why teeth with initially favorable periodontal prognosis are lost. It found that teeth with a history of root canal treatment have a higher likelihood of being lost due to caries, recurrent endodontic lesions, or fracture. Additionally, patients on anti-depressant medication, those with sporadic maintenance, initial probing depths >= 5 mm, and furcation involvement also have a significantly higher likelihood of tooth loss due to periodontal disease even for initially favorable teeth.
Article
Oncology
Jennifer K. Plichta, Christel N. Rushing, Holly C. Lewis, Marguerite M. Rooney, Dan G. Blazer, Samantha M. Thomas, E. Shelley Hwang, Rachel A. Greenup
Summary: This study evaluated the association between missing data and overall survival in national cancer registries and found that missingness of select variables is not uncommon and is associated with worse overall survival.
BREAST CANCER RESEARCH AND TREATMENT
(2023)
Article
Dentistry, Oral Surgery & Medicine
Ming Ding, Zhonghua Zhang, Zhu Chen, Jukun Song, Beichuan Wang, Fuqian Jin
Summary: This study used Mendelian randomization analysis to investigate the causal relationship between periodontitis and breast cancer. The results showed no significant causal relationship between periodontitis and breast cancer in both directions of analysis.
CLINICAL ORAL INVESTIGATIONS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Caroline Loureiro, Marilia Afonso Rabelo Buzalaf, Talita Mendes Oliveira Ventura, Vinicius Taioqui Pela, Gladiston William Lobo Rodrigues, Julia Guerra Andrade, Juliano Pelim Pessan, Rogerio Castilho Jacinto
Summary: This study quantitatively and qualitatively analyzed the proteomic profile of teeth with acute apical abscesses (AAA) and chronic apical periodontitis (CAP). The results showed significant differences in protein expression between the two groups, with AAA group mainly associated with immune inflammatory response and oxidative stress response, and CAP group mainly associated with DNA/RNA regulation and repair, and structural function.
CLINICAL ORAL INVESTIGATIONS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Eun Joo Kang, Seok-joo Moon, Kyoungmin Lee, In Hae Park, Jung Sun Kim, Yoon Ji Choi
Summary: Using a nationwide population cohort database, this study found that poor dental health, especially missing teeth, is highly associated with an increased risk of various cancers.
Article
Immunology
Vanessa Dominique Lobognon, Jean-Eric Alard
Summary: Periodontal diseases are inflammatory conditions caused by bacterial invasion and host defenses. Antimicrobial peptides (AMPs) play a critical role in the immune response, targeting microbes and modulating immune cells such as B-cells. Understanding the interaction between AMPs and B-cells could shed light on their recruitment, differentiation, and involvement in periodontal defense and destruction.
FRONTIERS IN IMMUNOLOGY
(2022)
Editorial Material
Dentistry, Oral Surgery & Medicine
Jukka H. Meurman
Article
Biochemistry & Molecular Biology
Jeneen Panezai, Azra Ali, Ambereen Ghaffar, Daniel Benchimol, Mohammad Altamash, Bjorn Klinge, Per-Erik Engstrom, Anders Larsson
Article
Dentistry, Oral Surgery & Medicine
Kathrin Becker, Katarzyna Gurzawska-Comis, Giulia Brunello, Bjorn Klinge
Summary: During the COVID-19 pandemic, European countries have developed dental care guidelines with general consensus on triage, mouth rinse, and personal protective equipment for aerosol generating procedures and treatment of potentially infectious patients. However, there is considerable variation in recommendations regarding personal protective equipment for non-aerosol generating procedures among the European countries.
CLINICAL ORAL IMPLANTS RESEARCH
(2021)
Article
Dentistry, Oral Surgery & Medicine
Giulia Brunello, Katarzyna Gurzawska-Comis, Kathrin Becker, Jurgen Becker, Stefano Sivolella, Frank Schwarz, Bjorn Klinge
Summary: The purpose of this study was to update European experts' opinions on infection control and prevention in dentistry during the second wave of the COVID-19 pandemic. The study found that overall transmission risk in dental settings had decreased compared to the first wave, but risk associated with aerosol-generating procedures remained high. Experts' recommendations for personal protective equipment (PPE) also showed some changes, with many still advising the use of FFP2/FFP3 masks, face shields, gowns, and caps.
CLINICAL ORAL IMPLANTS RESEARCH
(2021)
Article
Dentistry, Oral Surgery & Medicine
Katarzyna Gurzawska-Comis, Kathrin Becker, Giulia Brunello, Bjorn Klinge
Summary: The rapid publication and frequent updates of national guidelines in Europe were influenced by the dynamics of the pandemic. Due to the lack of solid evidence, expert opinions on ICP in dentistry were included. Dental care should be ensured during the pandemic, with treatment postponed in cases of suspected or confirmed COVID-19. Remote triage and patient-related measures were recommended to reduce SARS-CoV-2 transmission, along with appropriate personal protective equipment for dental staff based on procedure and infection risk.
CLINICAL ORAL IMPLANTS RESEARCH
(2021)
Review
Biochemical Research Methods
Timo Sorsa, Vaibhav Sahni, Nurcan Buduneli, Shipra Gupta, Ismo T. Raisanen, Lorne M. Golub, Hsi-Ming Lee, Tommi Patila, Nagihan Bostanci, Jukka Meurman, Pirjo Parnanen, Solomon O. Nwhator, Mohita Singla, Krishan Gauba
Summary: aMMP-8 is a potential biomarker for periodontal and peri-implant diseases, with POCT assays such as mouthrinse aMMP-8 being noninvasive and real-time for detection, treatment, and prevention. The clinical interdisciplinary utilization of aMMP-8 POCT requires further studies in oral, medical, and interdisciplinary fields.
EXPERT REVIEW OF PROTEOMICS
(2021)
Editorial Material
Dentistry, Oral Surgery & Medicine
J. H. Meurman
JOURNAL OF DENTAL RESEARCH
(2021)
Article
Dentistry, Oral Surgery & Medicine
Kristina Bertl, Johan Burisch, Nikolaos Pandis, Corinna Bruckmann, Bjorn Klinge, Andreas Stavropoulos
Summary: The aim of this questionnaire-based case-control study was to assess whether self-reported oral health and periodontitis differed in patients with ulcerative colitis (UC) and Crohn's disease (CD) compared to matched controls without inflammatory bowel disease (IBD). The study found that patients with UC and CD had significantly worse oral health and more severe periodontal problems compared to controls, with CD patients being more severely affected and losing more teeth. Close surveillance of IBD patients is strongly recommended to prevent periodontitis development and/or mitigate its progression.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Georgios N. Antonoglou, Mario Romandini, Jukka H. Meurman, Markku Surakka, Sok-Ja Janket, Mariano Sanz
Summary: This study investigated the association between periodontitis and edentulism with cardiovascular disease (CVD) and all-cause mortality. The results demonstrated a strong link between edentulism and CVD and all-cause mortality, while periodontitis showed no significant association.
JOURNAL OF PERIODONTAL RESEARCH
(2023)
Review
Dentistry, Oral Surgery & Medicine
Jukka H. Meurman, Michel Goldberg
Summary: Irma Thesleff is a prominent scholar in the field of developmental biology, known for her research on tooth development and morphogenesis. Her work has contributed to a better understanding of complex signaling networks. She has earned recognition both domestically and internationally, and continues her research even after retirement.
Article
Multidisciplinary Sciences
Lauri Jouhi, Jenna Sikio, Anni Suomalainen, Rayan Mroueh, Antti Makitie, Jukka H. Meurman
Summary: This study found that patients with oropharyngeal cancer generally had worse oral health compared to patients with oral tongue cancer, especially in the HPV-negative subgroup.
Article
Dentistry, Oral Surgery & Medicine
Anders Rosland, Randi J. Bertelsen, Dagmar F. Bunaes, Christine Drengenes, Gunnar Engstrom, Bjorn Klinge, Stein-Atle Lie, Peter M. Nilsson, Daniel Jonsson, Andrei Malinovschi
Summary: This study investigated the association between periodontitis and lung function in the Malmo Offspring Dental Study. The results showed that severe periodontitis was associated with lower lung function and airflow obstruction.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Kristina Bertl, Johan Burisch, Nikolaos Pandis, Bjorn Klinge, Andreas Stavropoulos
Summary: Patients with inflammatory bowel disease (IBD) have a higher frequency and impact of oral lesions and higher costs for professional dental care compared to matched controls.
JOURNAL OF PERIODONTOLOGY
(2023)
Review
Dentistry, Oral Surgery & Medicine
Jukka H. Meurman, Birgitta Soder
Summary: The Stockholm Studies, started in 1985 and ongoing, investigated the association between oral health parameters and systemic health outcomes among residents aged 30 and 40 in the greater Stockholm area in Sweden. The 35 years of observation revealed connections between periodontitis and various systemic health issues, supporting previous findings on the link between poor oral health and heart diseases and cancer.
Article
Dentistry, Oral Surgery & Medicine
Sakari Nikinmaa, Niina Moilanen, Timo Sorsa, Juha Rantala, Heikki Alapulli, Anja Kotiranta, Petri Auvinen, Esko Kankuri, Jukka H. Meurman, Tommi Patila
Summary: The study demonstrated the feasibility and initial efficacy of ICG-assisted aPDT for dental plaque, showing successful reduction of plaque-forming bacteria and anti-inflammatory and anti-proteolytic effects.