4.2 Article

MECHANISM OF BACTERICIDAL ACTIVITY OF SILVER NITRATE - A CONCENTRATION DEPENDENT BI-FUNCTIONAL MOLECULE

Journal

BRAZILIAN JOURNAL OF MICROBIOLOGY
Volume 41, Issue 3, Pages 805-809

Publisher

SOC BRASILEIRA MICROBIOLOGIA
DOI: 10.1590/S1517-83822010000300033

Keywords

Silver nitrate; Bacillus licheniformis; nanoparticle synthesis; apoptosis; DNA fragmentation

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Funding

  1. Tamilnadu State Council for Science and Technology (TNSCST)
  2. Council of Scientific and Industrial Research (CSIR) [37(1384)/09/EMR-II]

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Silver nitrate imparts different functions on bacteria depending upon its concentration. At lower concentration it induced synthesis of nanoparticles, whereas at higher concentrations it induced cell death. Bacillus licheniformis was used as model system. The MIC was 5 mM, and it induced catalase production, apoptotic body formation and DNA fragmentation.

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