Article
Parasitology
Agnieszka Piekara-Stepinska, Jolanta Piekarska, Michal Gorczykowski, Jacek Bania
Summary: This study aimed to determine the current epidemiological status of G. duodenalis in household dogs and cats, finding a detection rate of 6.0% in dogs and 3.9% in cats. The highest frequency was observed in young dogs, and sequencing confirmed the presence of host-specific assemblages and zoonotic assemblage A.
ACTA PARASITOLOGICA
(2021)
Article
Medicine, General & Internal
Saeideh Hashemi-Hafshejani, Ahmad Reza Meamar, Maryam Moradi, Nasrin Hemmati, Shahram Solaymani-Mohammadi, Elham Razmjou
Summary: The study identified the genetic diversity of G. duodenalis isolates in Tehran using multilocus sequence typing. Assemblages A and B were the main sources of infection in humans, and dual infections with both assemblages were common. Assemblage A isolates showed low genetic polymorphism, while assemblage B isolates had high genetic variations. Further research is needed to determine the specific multilocus genotypes and the transmission modes in different host populations.
FRONTIERS IN MEDICINE
(2022)
Article
Parasitology
Panpan Zhao, Jianhua Li, Xin Li, Jingquan Dong, Xiaocen Wang, Nan Zhang, Shan Li, Min Sun, Xichen Zhang, Zhibang Wang, Min Liang, Ying Li, Lili Cao, Pengtao Gong
Summary: This study found that parasitic organism G. duodenalis triggers host NLRP3 inflammasome activation through the secretion of extracellular vesicles (EVs), which regulates the host inflammatory response. The presence of alpha-2 and alpha-7.3 giardins in G. duodenalis also induces IL-1 beta secretion through the NLRP3 inflammasome in vivo, leading to a decrease in G. duodenalis infection ability.
PARASITES & VECTORS
(2023)
Article
Parasitology
Josephine S. Y. Hublin, Jenny G. Maloney, Nadja S. George, Aleksey Molokin, Jason E. Lombard, Natalie J. Urie, Chelsey B. Shivley, Monica Santin
Summary: Giardia duodenalis is a common parasitic cause of gastrointestinal illness worldwide. Conventional molecular methods underestimate the occurrence of mixed infections in cattle. Next generation amplicon sequencing demonstrates superior sensitivity in detecting mixed infections.
VETERINARY PARASITOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Isabel Guadano Procesi, Azzurra Carnio, Federica Berrilli, Margherita Montalbano Di Filippo, Alessia Scarito, Cristina Amoruso, Marco Barni, Marco Ruffini, Giulia Barlozzari, Manuela Scarpulla, Claudio De Liberato
Summary: The study detected and analyzed the genetic characteristics of G. duodenalis in colony stray cats in central Italy, revealing a surprisingly high prevalence of 35.3% in cats, with all positive cats being infected with zoonotic assemblages/sub-assemblages. This suggests that stray cats may serve as a possible source of human giardiasis and emphasizes the importance of cat colonies in the study area in terms of public health.
ZOONOSES AND PUBLIC HEALTH
(2022)
Review
Microbiology
Rodney D. Adam
Summary: Giardia duodenalis, initially observed by Leeuwenhoek in 1681, gained attention as a human pathogen in the 1960s. Advances in technology have provided insights into its biology and immunology, revealing the importance of a balanced host immune response and the role of the Th17 response. Infection with Giardia can result in a wide range of symptoms, highlighting the complexity of host-parasite interactions.
CLINICAL MICROBIOLOGY REVIEWS
(2021)
Article
Microbiology
Julia Smigova, Viliam Snabel, Serena Cavallero, Lubomir Smiga, Jindrich Soltys, Jan Papaj, Ingrid Papajova
Summary: This study investigated the occurrence of parasitic infections in children in Slovakia and performed molecular characterization of the parasites. The findings suggest that poverty and poor hygiene contribute the most to public health problems associated with neglected parasitic diseases.
Article
Food Science & Technology
Xiang-Zhu Meng, Chao Kang, Jiaqi Wei, He Ma, Gang Liu, Jin-Ping Zhao, Hong-Shun Zhang, Xin-Bo Yang, Xiang-Yu Wang, Li-Hua Yang, Hong-Li Geng, Hongwei Cao
Summary: A systematic literature review and meta-analysis revealed that the overall prevalence of Giardia duodenum in cattle in China was 8.00% (95% CI: 5.51-11.62). Calves had a significantly higher prevalence than other age groups, and the prevalence was higher in summer compared to other seasons. The prevalence after 2016 was significantly higher than before 2016, and the highest prevalence was recorded in South China.
FOODBORNE PATHOGENS AND DISEASE
(2023)
Article
Microbiology
Andrea Agresti, Federica Berrilli, Michela Maestrini, Isabel Guadano Procesi, Enrico Loretti, Niccolo Vonci, Stefania Perrucci
Summary: The prevalence, genotypes, and potential risk factors of Giardia duodenalis were investigated in sheltered dogs from four kennels in central Italy. The study found a high prevalence of G. duodenalis and identified potentially zoonotic genotypes. The presence of other intestinal parasites was also observed. The findings highlight the need for improved parasite monitoring and control measures and provide insights into the zoonotic potential of G. duodenalis.
Article
Veterinary Sciences
Brent R. Dixon
Summary: Giardia duodenalis is a protozoan parasite that infects the upper intestinal tract of humans and animals worldwide. Transmission occurs through the fecal-oral route and can lead to a wide range of gastrointestinal symptoms. Diagnosis is typically made by detecting cysts in stool samples, and treatment aims to reduce symptoms, prevent complications, and minimize transmission.
RESEARCH IN VETERINARY SCIENCE
(2021)
Article
Immunology
Ana Clecia dos santos Silva, Felippe Danyel Cardoso Martins, Winni Alves Ladeia, Monica Tiemi Aline Kakimori, Juliana Izidoro Lucas, Jao Pedro Sasse, Thais Agostinho Martins, Vilma de Fattima Rodrigues de Macedo, Valter Abou Murad, Luiz Daniel de Barros, Joao Luis Garcia
Summary: The present study molecularly characterized Giardia duodenalis from stool samples of humans, dogs, and cats, revealing the presence of different assemblages and providing new insights into the epidemiological understanding of giardiasis.
COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES
(2022)
Article
Veterinary Sciences
Carolina Beatriz Baptista, Matheus Janeck Araujo, Sandra Valeria Inacio, Bruno Criado de Araujo Mendes, Monally Conceica Costa de Aquino, Elis Domingos Ferrari, Katia Denise Saraiva Bresciani, Alvimar Jose da Costa
Summary: This study reports, for the first time, the occurrence of G. duodenalis assemblage A in pet rabbits in Brazil. PCR analysis of fecal samples from 100 rabbits revealed 40 positive cases. This research is important for understanding parasite infections in Brazilian rabbits.
PREVENTIVE VETERINARY MEDICINE
(2023)
Article
Microbiology
Michela Maestrini, Federica Berrilli, Alessia Di Rosso, Francesca Coppola, Isabel Guadano Procesi, Alessia Mariacher, Antonio Felicioli, Stefania Perrucci
Summary: This study investigated the occurrence and species of gastrointestinal parasites in a free-ranging badger population in a highly anthropic area in central Italy. The results showed that 86% of the samples were positive, with G. duodenalis, Cryptosporidium spp., and coccidian oocysts being the most commonly detected parasites. The zoonotic potential of G. duodenalis and other identified parasites highlights the importance of population health in wild badgers and other animals.
Article
Microbiology
Deiviane A. Calegar, Beatriz C. Nunes, Kerla J. L. Monteiro, Polyanna A. A. Bacelar, Brenda B. C. Evangelista, Mayron M. Almeida, Jurecir Silva, Jessica P. Santos, Marcio N. Boia, Lauren H. Jaeger, Filipe A. Carvalho-Costa
Summary: Subclinical giardiasis is endemic in Brazilian communities in different biogeographic regions, showing high genetic diversity and heterogeneous genotypic distribution.
Article
Infectious Diseases
Sahana Kuthyar, Martin M. Kowalewski, Matthew Seabolt, Dawn M. Roellig, Thomas R. Gillespie
Summary: The study revealed that in a complex environment where humans, domesticated animals, and wildlife overlap in rural areas of northern Argentina, cross-species transmission of multiple assemblages of Giardia duodenalis may occur, with monkeys having the highest infection rate. Human and domesticated animals were found to be infected with assemblage A, while humans and wild primates were infected with assemblage B.
TRANSBOUNDARY AND EMERGING DISEASES
(2022)
Article
Public, Environmental & Occupational Health
Myrela C. S. Jesus, Rynat D. O. Chagas, Matheus L. J. Santos, Rafaela W. F. Santos, Roseli La Corte, Luciane M. Storti-Melo
Summary: This study aimed to assess the presence of DENV and ZIKV in Ae. aegypti females in Sergipe, Brazil during a non-epidemic year. The results showed the presence of ZIKV and DENV infection in a certain percentage of samples, as well as coinfected vectors. The findings highlight the importance of maintaining vigilance during non-epidemic years to prevent new outbreaks.
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE
(2022)
Review
Biotechnology & Applied Microbiology
Gabrielle Alves Ribeiro da Silva, Simone Santos de Sousa Oliveira, Sara Fernandes Lima, Rodrigo Pires do Nascimento, Andrea Regina de Souza Baptista, Sorele Batista Fiaux
Summary: Gluconobacter oxydans is a widely used acetic acid bacterium with the ability to oxidize sugars, polyols, and alcohols into valuable compounds. Recent research has focused on improving industrial applications through metabolic engineering and exploring low-cost feedstocks. Further investigation is needed to make these processes feasible at an industrial scale and overcome the lack of suitable genetic tools for metabolic engineering modifications in G. oxydans.
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
(2022)
Article
Microbiology
Lais Cavalcanti dos Santos Velasco de Souza, Nathalia Faria Reis, Lucas Martins Alcantara, Simone Rocha Leal da Silveira Souto, Bruno de Araujo Penna, Renan Caetano Souza Santos, Bruno Kaufmann Robbs, Francisco Paiva Machado, Helena Carla Castro, Ricardo Luiz Dantas Machado, Leandro Rocha, Andrea Regina de Souza Baptista
Summary: This study aimed to evaluate the efficacy of different fractions of plant extracts against itraconazole-sensitive and low susceptibility Sporothrix brasiliensis isolates. Ethyl acetate extracts from Ocotea notata and Myrciaria floribunda exhibited the highest antimicrobial activities against sensitive S. brasiliensis. These extracts may serve as potential alternative therapies for this neglected zoonosis, but further research is needed.
BRAZILIAN JOURNAL OF MICROBIOLOGY
(2023)
Letter
Microbiology
Juliana Pedrosa, Luiza Aymee, Julia Andrade de Castro Rodrigues, Nathalia Faria Reis, Andrea Regina de Souza Baptista, Walter Lilenbaum
VETERINARY MICROBIOLOGY
(2023)
Article
Infectious Diseases
Simone Cristina Pereira Brito, Marcia Ribeiro Pinto, Lucas Martins Alcantara, Nathalia Faria Reis, Thiago Lacerda Duraes, Christina Teresa Machado Bittar, Jeferson Carvalhaes de Oliveira, Elisabeth Martins da Silva da Rocha, Ricardo Luiz Dantas Machado, Ricardo Jose de Paula Souza e Guimaraes, Andrea Regina de Souza Baptista
Summary: This retrospective study investigated epidemiological and laboratorial aspects of dermatophytosis in Rio de Janeiro state, Brazil, by using spatiotemporal analysis. More than half of all individuals were infected by one or more dermatophytes. The distribution of dermatophytosis varied among different age groups and regions, highlighting the need for specific prevention and control measures in touristic tropical localities.
PLOS NEGLECTED TROPICAL DISEASES
(2023)
Article
Biochemistry & Molecular Biology
Myrela C. S. de Jesus, Marcelo Cerilo-Filho, Aina D. R. Ramirez, Rubens A. O. Menezes, Margarete S. M. Gomes, Gustavo C. Cassiano, Ricardo Q. Gurgel, Jose R. S. Silva, Tatiana R. Moura, Lilian R. Pratt-Riccio, Andrea R. S. Baptista, Luciane M. Storti-Melo, Ricardo L. D. Machado
Summary: This study aimed to describe the allelic and genotypic frequency of four polymorphisms in the trem-1 gene in Plasmodium vivax-infected patients and to verify their association with clinical and immunological factors. The study found that these SNPs in the trem-1 gene are associated with effector molecules of the innate immunity, and may be essential for the establishment of immunization strategies against malaria.
Article
Biochemistry & Molecular Biology
Aina D. R. Ramirez, Myrela C. S. de Jesus, Rubens A. O. Menezes, Marcelo C. Santos-Filho, Margarete S. M. Gomes, Tamirys S. Pimenta, Vanessa S. Barbosa, Julia Rossit, Nathalia F. Reis, Simone Cristina Pereira Brito, Marrara Pereira Sampaio, Gustavo C. Cassiano, Luciane M. Storti-Melo, Andrea R. S. Baptista, Ricardo L. D. Machado
Summary: This study evaluated the association between five polymorphisms in TLR-4, TLR-6, and TLR9 genes and cytokine levels and clinical parameters in malaria from the Brazil-French Guiana border. An association between TLR4 A299G with parasitemia was observed. Increased levels of IFN-gamma, TNF-alpha, IL-6, and IL-10 were found in certain TLR-4, TLR-6, and TLR-9 gene polymorphisms. The immune response observed varied depending on the human population and Plasmodium species.
Article
Multidisciplinary Sciences
Thiago Vizine Da Cruz, Ricardo Luiz Machado
Summary: This study analyzed the impact of climate change on sugarcane production and found that climate had negligible effects on yield when different varieties were taken into account. Therefore, the Brazilian government should continue to incentivize the development and use of new sugarcane varieties to promote sustainable production and contribute to achieving the Sustainable Development Goals (SDGs).
SCIENTIFIC REPORTS
(2023)
Article
Health Care Sciences & Services
Amy Ibrahim, Emilia Manko, Jamille G. Dombrowski, Monica Campos, Ernest Diez Benavente, Debbie Nolder, Colin J. Sutherland, Francois Nosten, Diana Fernandez, Gabriel Velez-Tobon, Alberto Tobon Castano, Anna Caroline C. Aguiar, Dhelio Batista Pereira, Simone da Silva Santos, Martha Suarez-Mutis, Silvia Maria Di Santi, Andrea Regina de Souza Baptista, Ricardo Luiz Dantas Machado, Claudio R. F. Marinho, Taane G. Clark, Susana Campino
Summary: Through whole genome sequencing of P. vivax isolates from 7 Brazilian states, researchers have identified distinct genetic diversity of P. vivax parasites in Brazil compared to other global regions. They have also discovered mutations in genes under selective pressure linked to antimalarial drugs and mosquito vectors. This study provides important insights into the population structure of P. vivax in Brazil and can inform future research and control measures.
LANCET REGIONAL HEALTH-AMERICAS
(2023)
Article
Green & Sustainable Science & Technology
Thiago Vizine Da Cruz, Ricardo Luiz Machado
Summary: The use of proper sugarcane varieties can mitigate the impact of climate change on production and improve eco-efficiency. This research identified more efficient sugarcane varieties through econometric analysis and data envelopment analysis. The findings contribute to achieving the United Nations SDGs 1, 2, 7, 9, and 15.
