Journal
BRAIN TUMOR PATHOLOGY
Volume 28, Issue 1, Pages 77-81Publisher
SPRINGER TOKYO
DOI: 10.1007/s10014-010-0003-3
Keywords
Histopathology; Arachnoid villi; Spinal meningioma
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Funding
- Grants-in-Aid for Scientific Research [22791342] Funding Source: KAKEN
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Although the histogenesis of meningiomas remains unclear, it is believed that arachnoid cells are the most likely origin of this type of neoplasm. Further, little attention has been paid to the histopathology of spinal meningiomas arising from the arachnoid villi. We came across a case of spinal meningioma that was locally attached to the arachnoid membrane. The associated arachnoid villi were investigated by light microscopy and immunohistochemical analysis. We confirmed the presence of tumor cells under the fibrous capsule that forms the outer component of the arachnoid villi. Tumor cells grew out from the apical portion of the arachnoid villi. Furthermore, immunohistochemical study suggested that arachnoid cells made the transition to tumor cells on the arachnoid cell layer.
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