Article
Neurosciences
Christa Mueller-Axt, Cornelius Eichner, Henriette Rusch, Louise Kauffmann, Pierre-Louis Bazin, Alfred Anwander, Markus Morawski, Katharina von Kriegstein
Summary: This study demonstrates that quantitative MRI methods can be used to assess the microstructural features of the human lateral geniculate nucleus (LGN) and its subdivisions, providing insights into the functional and structural characteristics of the LGN in humans.
Article
Multidisciplinary Sciences
Yujie Wu, Tian Wang, Tingting Zhou, Yang Li, Yi Yang, Weifeng Dai, Yange Zhang, Chuanliang Han, Dajun Xing
Summary: The study reveals the emergence of direction-specific microsaccade modulation in the middle layer of V2, with stronger responses of V2 neurons when microsaccades moved towards their receptive fields compared to when they moved away. The findings suggest a V1-bypassing suppressive circuit for direction-specific microsaccade modulation in V2, highlighting the optimal sampling nature of microsaccades.
NATURE COMMUNICATIONS
(2022)
Article
Neurosciences
Shraddha Shah, Marc Mancarella, Jacqueline R. Hembrook-Short, Vanessa L. Mock, Farran Briggs
Summary: Attention enhances the selection of behaviorally relevant sensory signals and modulates neuronal activity in visual brain areas, with attention gain magnitudes varying across different brain regions. Discrepancies in attention effects between humans and monkeys are not simply due to species or measurement differences, but rather reflect unique properties of each visual brain area. The feature selectivity of recorded multiunit activity plays a role in attentional modulation across visual brain areas.
JOURNAL OF COMPARATIVE NEUROLOGY
(2022)
Article
Biochemistry & Molecular Biology
James E. Niemeyer, Seth Akers-Campbell, Aaron Gregoire, Michael A. Paradiso
Summary: The study found that real saccadic eye movements affect neural activity and perceptual sensitivity in V1, with low spatial frequency stimuli showing reduced sensitivity and activity compared to simulated saccades, while higher spatial frequency stimuli showed increased sensitivity and activity. This suggests that signals related to saccades alter V1 spiking activity to increase neural independence and bias towards processing higher spatial frequencies for object recognition.
Article
Neurosciences
Denghui Liu, Shouhao Li, Liqing Ren, Xiaoyuan Li, Zhenlong Wang
Summary: Animals rely on vision to perceive threat information, and the superior colliculus and lateral posterior nuclei are key components in the subcortical visual pathway. Research shows that these nuclei strongly respond to looming visual stimuli but are not sensitive to dimming visual stimuli. Under looming visual stimuli, there are evident oscillations in the theta frequency bands of these nuclei, enhancing synchronization between neurons and improving information transmission efficiency.
Article
Neurosciences
Paul Glad Mihai, Nadja Tschentscher, Katharina von Kriegstein
Summary: The study shows that task-dependent modulation in speech recognition increases with sensory uncertainty in the speech signal, particularly in the ventral MGB providing driving input to the auditory cortex for speech in noisy listening conditions.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Biology
Mahmood S. Hoseini, Bryan Higashikubo, Frances S. Cho, Andrew H. Chang, Alexandra Clemente-Perez, Irene Lew, Agnieszka Ciesielska, Michael P. Stryker, Jeanne T. Paz
Summary: The study identified SST neurons in the nRT as powerful modulators of visual information encoding accuracy in V1, highlighting a novel circuit through which the nRT can influence the representation of visual information.
Article
Anatomy & Morphology
Ulrike Gruenert, Sammy C. S. Lee, William C. Kwan, Inaki-Carril Mundinano, James A. Bourne, Paul R. Martin
Summary: The study identified the retinal ganglion cell types projecting to the medial subdivision of inferior pulvinar and superior colliculus in marmoset monkeys. Results showed that both PIm and SC receive input from various ganglion cell types, with different dominant cell types in each area.
BRAIN STRUCTURE & FUNCTION
(2021)
Article
Behavioral Sciences
James M. Shine
Summary: The thalamus and superior colliculus play crucial roles in higher-order functions of the brain, such as working memory and attention. The connections between them and their location within the brain circuitry shape complex dynamics and conscious awareness. This perspective leads to testable predictions about the interactions between different regions within the thalamus.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2022)
Article
Psychology, Multidisciplinary
Luis Carretie, Raghunandan K. Yadav, Constantino Mendez-Bertolo
Summary: Several thalamic structures, including the lateral geniculate nucleus (LGN) and the thalamic reticular nucleus (TRN), are proposed as the earliest detectors of affective stimuli. These structures are crucial for processing emotional stimuli, especially in early emotional evaluation.
Article
Biochemistry & Molecular Biology
Ubadah Sabbagh, Gubbi Govindaiah, Rachana D. Somaiya, Ryan Ha, Jessica C. Wei, William Guido, Michael A. Fox
Summary: This study identified novel neuronal cell types in mouse vLGN using various techniques, revealing distinct GABAergic cell types in different laminae of vLGN. The results suggest that the subtype-specific laminar distribution of retinorecipient cells in vLGNe may play a crucial role in receiving, processing, and transmitting light-derived signals in parallel channels of the subcortical visual system.
JOURNAL OF NEUROCHEMISTRY
(2021)
Article
Neurosciences
Rachana D. Somaiya, Natalie A. Huebschman, Lata Chaunsali, Ubadah Sabbagh, Gabriela L. Carrillo, Bhanu P. Tewari, Michael A. Fox
Summary: The study investigated the transcriptional identity and development of astrocytes in the mouse visual thalamus, revealing that these cells have acquired adult-like morphology and functional characteristics before eye-opening. The results also showed that thalamic astrocytes ensheathe retinogeniculate synapses and are capable of efficient uptake of glutamate by eye-opening.
JOURNAL OF COMPARATIVE NEUROLOGY
(2022)
Article
Multidisciplinary Sciences
Zvi N. Roth, Kendrick Kay, Elisha P. Merriam
Summary: This study investigates whether orientation-selectivity is discernable via fMRI through analyzing a public dataset of responses to natural scenes using neurally-inspired image-computable models. It demonstrates that orientation-selective BOLD responses reflect multiple distinct computations and reveals a coarse-scale map of orientation preference that may constitute the neural basis for known perceptual anisotropies.
NATURE COMMUNICATIONS
(2022)
Article
Multidisciplinary Sciences
Michael Lohse, Johannes C. Dahmen, Victoria M. Bajo, Andrew J. King
Summary: This study demonstrates the importance of integrating multisensory signals through connections from the primary somatosensory cortex to the auditory midbrain and thalamus, allowing tactile inputs to modulate auditory processing. It highlights the critical role of crossmodal corticofugal projections in communication between different sensory cortical areas.
NATURE COMMUNICATIONS
(2021)
Review
Neurosciences
Alexander Asilador, Daniel A. Llano
Summary: The article discusses the widespread acceptance that humans use contextual information to infer the meaning of ambiguous acoustic signals, as well as the current theories and models used to explain this phenomenon. It also highlights the importance of the corticofugal pathways in the brain in this process, and the predictive coding mechanisms that modulate perception of complex sounds.
FRONTIERS IN NEURAL CIRCUITS
(2021)
Article
Behavioral Sciences
Peiyan Wong, Ying Sze, Laura Jane Gray, Cecilia Chin Roei Chang, Shiwei Cai, Xiaodong Zhang
FRONTIERS IN BEHAVIORAL NEUROSCIENCE
(2015)
Article
Multidisciplinary Sciences
Nicholas W. Bellono, Duncan B. Leitch, David Julius
Article
Psychology, Biological
Feng Ru Tang, Weng Keong Loke, Peiyan Wong, Boo Cheong Khoo
PHYSIOLOGY & BEHAVIOR
(2017)
Article
Multidisciplinary Sciences
Nicholas W. Bellono, Duncan B. Leitch, David Julius
Article
Behavioral Sciences
Peiyan Wong, J. Klint Peebles, Christopher L. Asplund, Christine E. Collins, Suzana Herculano-Houzel, Jon H. Kaas
BRAIN BEHAVIOR AND EVOLUTION
(2013)
Article
Neurosciences
Eva K. Sawyer, Duncan B. Leitch, Kenneth C. Catania
JOURNAL OF COMPARATIVE NEUROLOGY
(2014)
Article
Multidisciplinary Sciences
Long N. Nguyen, Dongliang Ma, Guanghou Shui, Peiyan Wong, Amaury Cazenave-Gassiot, Xiaodong Zhang, Markus R. Wenk, Eyleen L. K. Goh, David L. Silver
Article
Multidisciplinary Sciences
Peiyan Wong, Vonny I. Leo, Meijun Low, Tak W. Mak, Xiaodong Zhang, Patrick T. Reilly
Article
Multidisciplinary Sciences
Duncan B. Leitch, Diana K. Sarko, Kenneth C. Catania
SCIENTIFIC REPORTS
(2014)
Article
Biochemistry & Molecular Biology
Wan Yun Ho, Jer-Cherng Chang, Sheue-Houy Tyan, Yi-Chun Yen, Kenneth Lim, Bernice Siu Yan Tan, Jolynn Ong, Greg Tucker-Kellogg, Peiyan Wong, Edward Koo, Shuo-Chien Ling
HUMAN MOLECULAR GENETICS
(2019)
Article
Biochemistry & Molecular Biology
Wei Wang, Ping Xiang, Wee Siong Chew, Federico Torta, Aishwarya Bandla, Violeta Lopez, Wei Lun Seow, Brenda Wan Shing Lam, Jing Kai Chang, Peiyan Wong, Kanokporn Chayaburakul, Wei-Yi Ong, Markus R. Wenk, Raghav Sundar, Deron R. Herr
JOURNAL OF BIOLOGICAL CHEMISTRY
(2020)
Article
Education, Scientific Disciplines
Irene Cheng Jie Lee, Peiyan Wong, Suzanne Pei Lin Goh, Sandy Cook
Summary: The COVID-19 pandemic has shifted medical curriculum delivery from in-person to online, potentially impacting important competencies in medical education such as team cohesion and professional identity formation. To mitigate the impact of prolonged social isolation, synchronous team-based learning classes were conducted with practical tips provided.
MEDICAL SCIENCE EDUCATOR
(2022)
Article
Geriatrics & Gerontology
Peiyan Wong, Wan Yun Ho, Yi-Chun Yen, Emma Sanford, Shuo-Chien Ling
NEUROBIOLOGY OF AGING
(2020)
Article
Biochemistry & Molecular Biology
Nicholas W. Bellono, James R. Bayrer, Duncan B. Leitch, Joel Castro, Chuchu Zhang, Tracey A. O'Donnell, Stuart M. Brierley, Holly A. Ingraham, David Julius
Review
Gastroenterology & Hepatology
Joel Selkrig, Peiyan Wong, Xiaodong Zhang, Sven Pettersson